Mauck Laboratory

Lance Murphy

MD/PhD Student
University of Pennsylvania

Hometown

Columbia, SC

Education

B.S., Biomedical Engineering, Columbia University

Areas of Special Interest

Inflammation in MSK, Immunology, Tissue Regeneration, Regenerative Medicine

Awards

BME Department Recognition for Graduate Exhibiting Excellence Columbia University CP Davis Scholar

About me

Lance is an entrepreneur at heart. When he is not in lab, he is working on his small business wine company. He also can be found also taking advantage of the economic benefits of a happy hour. Lance loves his dog Jax and his fish Ginkgo

Publications

Pellicore, MJ, Gangi LR, Murphy LA, Lee AJ, Jacobsen T, Kenaway HM, Shah RP, Chahine NO, Ateshian, GA, Hung, CT. “Toward defining the role of the synovium in mitigating normal articular cartilage wear and tear.” Jounral of Biomechanics. 2023

Estell EG, Murphy LA, Silverstein AM, Tan AR, Shah R, Ateshian AG, Hung CT. “Fibroblast-like Synoviocyte Mechanosensitivity to Fluid Shear is Modulated by Interleukin-1α.” Journal of Biomechanics, 60: 91-99 (2017)

Estell EG, Murphy LA, Gangi LR, Shah RS, Ateshian GA, Hung CT. “Attachment of Cartilage Wear Particles to the Synovium Negatively Impacts Friction Properties.” Journal of Biomechanics

Conference Abstracts and Presentations 

Podium
1. Murphy LA, Gangi LR, Shaeffer, CA, Stefani RM, Jacobsen T, Kenaway HM, Shah RP, Trofa, DP, Chahine NO, Ateshian, GA, Hung, CT. “Toward defining the role of the synovium in mitigating normal articular cartilage wear and tear.” SB3C 2020
2. Murphy LA, Gangi LR, Stefani RM, Kenawy HM, Lee AJ, Ateshian GA, Shah RP, Hung CT. Interleukin-1a Decreases Coefficient of Friction of Synovium ex vivo. ORS 2020. 
3. Murphy LA, Rogot JT, Sakhrani N, Stefani RM, Lee AJ, Ateshian GA, Shah RP, Thomopolous S, Hung CT. Synovial Wrap for Supporting Primary Intra-Articular Ligament Repair. ORS 2020.
4. Murphy LA, Barbosa S, Estell EG, Tan AR, Hung CT. Cell-Cycle Synchronization Regulates Cell Mechanotransduction and Improves Cartilage Tissue Engineering Outcomes. ISEL Santiago, Chile 2017.
Posters
Murphy LA, Peredo, AP, Gullbrand, SE, Mauck RL. “Interleukin-1β as a Neuroinflammatory Mediator in Intervertebral Disc Injury” ORS 2022
Murphy LA, Rogot JT, Sakhrani N, Stefani RM, Lee AJ, Ateshian GA, Shah RP, Thomopolous S, Hung CT. Synovial Wrap for Supporting Primary Intra-Articular Ligament Repair. Engineering in Medicine Symposium.
Murphy LA. Lee A, Stefani RM, Kenawy HM, Gangi LR, Ateshian GA, Shah RP, Thomopolous S, Hung CT. Development of a Synovial Wrap for Intra-Articular Ligament Repair. BMES 2019.
Murphy LA, Stefani RM, Estell EG, Gangi LR, Kenawy HM, Ateshian GA, Shah, RP, Hung CT. Wound Healing of PCL Fibroblasts is Inhibited by Synovial Fibroblasts Production of Hyaluronan. ORS 2019.
Murphy LA, Estell EG, Hung CT. Characterization of Synovial Fibroblast Fluid Shear Mechanosensing. SURF Symposium 2016
 

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