Job opportunities

Our lab welcomes talented and highly motivated individuals from a variety of backgrounds and expertise. We are currently recruiting team members for the following positions.

The Research Specialist B at the Center for Cytokine Storm Treatment and Laboratory (CSTL) will help facilitate Castleman disease and cytokine storm-related research projects, performing conceptual and wet-lab research with opportunities to work on data-driven projects. Under the Senior Research Investigator of the CSTL, the Research Specialist B will be tasked with culturing human primary cells, performing in vitro stimulation experiments, immunohistochemistry/immunofluorescence, and flow cytometry, and will work with large-scale clinical research data. In addition, the Research Specialist B will assist the Senior Research Investigator with research projects that involve cutting-edge genomics’ technologies. The position offers opportunities for professional growth and scientific experiences on a collaborative and hardworking team. The individual will be expected to participate in lab meetings, discussions, and assist with experiments of other lab members. The applicant must be well organized and is expected to maintain a lab notebook. Additional responsibilities will include organizing/ordering materials and reagents for the lab, dealing with vendors, and sharing lab maintenance duties with other lab members.

 

Qualified candidates will have expertise in research planning, in vitro and in vivo experiments, and a background in biology with a general interest in immunology and inflammatory disorders. Joining the CSTL offers scientific professionals the unique opportunity of seeing their research go from bench to bedside and making discoveries that could one day lead to cures for deadly conditions such as COVID-19 and Castleman disease.

 

Position contingent upon funding.

To learn more about this opportunity and/or to apply visit the full listing here.  

If you have any additional questions after reviewing the full listing, please email CSTL@pennmedicine.upenn.edu.  

The CSTL, in partnership with the Division of Translational Medicine & Human Genetics and the Fajgenbaum lab, is now expanding CORONA (COVID19 Registry of Off-label & New Agents) to include additional data sources and searching for a talented, experienced, and motivated data scientist to perform analyses on this expansive dataset and generate meaningful insights. The project will integrate and track pre-clinical treatment data and real-world data (medical records and insurance claims) and enable the search for treatment patterns, identification of promising drugs that need to be evaluated in clinical trials, and facilitate the development of recommendations to strengthen the global effort to combat COVID-19 and other diseases. In one place, government agencies, academic researchers, philanthropic organizations, and biopharmaceutical companies will be able to access all data at no cost on all potential treatments. The data scientist will be tasked with conceptualizing and developing analytical plans, supporting database development, performing analyses of data, interpreting results, and collaborating with government, industry, philanthropic, and academic partners. This position offers the opportunity to interface broadly with internal and external stakeholders from around the world to assure rapid progression of the science towards medical breakthroughs that help patients. Beyond COVID-19, there are exciting opportunities to perform analyses to elucidate understanding of other cytokine storm disorders with major unmet medical need as well as the thousands of diseases that currently have no treatments. The CSTL combines ‘omic analyses of patient biospecimens, hypothesis-driven basic science research, and clinical data analyses to discover and pursue novel therapeutic approaches for cytokine storm disorders through clinical trials and adoption in clinical practice. A talented data scientist is needed to perform these multi-omic analyses. We are additionally pursuing broad efforts to identify potential drugs to be repurposed for any untreated disease.

 

Qualified candidates will have expertise in R and other coding languages and experience with medical informatics. Familiarity with database development, drug repurposing, NGS analyses, bioinformatics/computational biology, virology, and immunology is a plus. This is a unique opportunity to join a highly motivated, patient-focused team that works closely with international collaborators and the federal government to make and publish novel discoveries that will have a significant impact on patients who have COVID-19 and other diseases with major unmet medical need.

 

Position contingent upon funding.

To learn more about this opportunity and/or to apply visit the full listing here

If you have any additional questions after reviewing the full listing, please email CSTL@pennmedicine.upenn.edu.  

The Clinical Research Coordinator’s primary responsibilities will involve identifying, interpreting and extracting key medical record data into the registry database from patients in the U.S. and integrating multiple data sources to assess response to therapies, adverse events, and clinical courses, in collaboration with the Principal Investigator and Associate Director. They may also be responsible for reviewing patient hematopathology and selecting lymph node slides for the study Certification and Access Subcommittee. They will occasionally interact directly with Castleman disease patients, manage data extraction protocols, track metrics, prepare tables, graphs and descriptive summaries of data for presentations, progress reports, grant applications and manuscripts. They may also be expected to initiate and independently drive forward other projects in the CSTL, such as analyzing immunofluorescence, immunohistochemistry, or in situ hybridization or contributing to studies related to hematopathology.

 

Candidates must possess strong organizational skills and attention to detail; willingness to take initiative; ability to work independently but also know when to seek help, and to work as part of a fast paced and integrated team. The individual must possess strong decision making skills and the ability to work uninterrupted on a focused project. Experience reviewing medical records is a plus but not required.

 

Position contingent upon funding.

To learn more about this opportunity and/or to apply visit the full listing here

If you have any additional questions after reviewing the full listing, please email CSTL@pennmedicine.upenn.edu.