2 12 18
28
32
a
    6d
    • a 4f
  • Faculty
    • 22
  • Craig H. Bassing
    • b
8
1a 2a

Faculty

61 16
19
1b
35

Craig H. Bassing, Ph.D.

78 faculty photo 53
Professor of Pathology and Laboratory Medicine
7 78
Department: Pathology and Laboratory Medicine
4 1 23
1f Graduate Group Affiliations 8 a
b
1d
46 Contact information
 51
Children's Hospital of Philadelphia
25 1353 Abramson Research Center
3a 3615 Civic Center Blvd.
Philadelphia, PA 19104
26
2e Office: 267-426-0311
32 Fax: 267-426-2791
24
9d
Email: bassing@pennmedicine.upenn.edu
12
4 3 3 3 2 4 b 1f
13 Education:
21 9 B.A. 14 (Biology) c
35 The Johns Hopkins University, 1992.
 21 a Ph.D. 14 (Biology) c
28 Duke University, 1997.
 c
3 27
Links
60 Cancer Biology
c
5 3 3 92 Permanent link
2 29
 
1d
25
21
b6 > Perelman School of Medicine   > Faculty   > Details a
1e 1d
2b 29
23

Selected Publications

123 Glynn, R.A. and Bassing, C.H.: ATM-Dependent Phosphorylation of Nemo SQ Motifs is Dispensable for Nemo-Mediated Gene Expression Changes in Response to DNA Double Strand Breaks. The Journal of Immunology In Press, 2024.

 137 Allyn, B.M., Hayer, K.E., Oyeniran, C., Nganga, V., Lee, K., Mishra, B., Sacan, A., Oltz, E.M., and Bassing, C.H.: Locus Folding Mechanisms Determine Modes of Antigen Receptor Gene Assembly. The Journal of Experimental Medicine 221, 2024.

 14c Culberson, E.J., Shields, K.C., Glynn, R.A., Allyn, B.M., Hayer, K.E., and Bassing, C.H.: The Cyclin D3 Protein Enforces Monogenic TCRb Expression by Mediating TCRb Protein Signaled Feedback Inhibition of Vb Recombination The Journal of Immunology 212, 2024.

 cc Burn, T.N., Miot, C., Gordon, S.M., Culberson, E.J., Diamond, T., Kreiger, P.A., Hayer, K.E., Bhattacharyya, A., Jones, J.M., Bassing, C.H.*, and Behrens, E.M.* de *Co-corresponding authors: The RAG1 Ubiquitin Ligase Domain Stimulates Recombination of TCRb and a Genes and Influences Development of ab T Cell Lineages. The Journal of Immunology 209, 2022.

 11a Glynn, R.A. and Bassing, C.H.: Nemo-dependent, ATM-mediated signals from RAG DNA breaks at Igk feedback inhibit Vk recombination to enforce Igκ allelic exclusion. The Journal of Immunology 208: 371-383, 2022.

 15b Wu, G., Culberson, E.J., Allyn, B.M., and Bassing, C.H.: Poor-Quality Vb Recombination Signal Sequences and the DNA Damage Response ATM Kinase Collaborate to Establish TCRb Gene Repertoire and Allelic Exclusion. The Journal of Immunology doi: 10.4049/jimmunol.2100489, 2022.

 10d Culberson, E.J. and Bassing, C.H.: Monogenic TCRb Assembly and Expression is Paramount for Uniform Antigen Receptor Specificity of Individual ab T Lymphocytes. The Journal of Immunology 209, 2022.

 1e4 Beilinson, H.A., Glynn, R.A., Yadavailli, A.D., Xiao, J., Corbett, E., Saribasak, H., Arya, R., Miot, C., Bhattacharyya, A., Jones, J.M., Pongubala, J., Bassing, C.H., and Schatz, D.G. : The RAG1 N-terminal region regulates the efficiency and pathways of synapsis for V(D)J recombination. Journal of Experimental Medicine. Oct 4;218(10):e20210250. doi: 10.1084/jem.20210250. (eds.). 218(10): :e20210250, 2021.

 ff Dauphers, D.J., Wu, G.S., Bassing, C.H., and Krangel, M.S.: Molecular Analysis of Mouse T Cell Receptor α and β Gene Rearrangements Methods in Molecular Biology In Press, 2021.

 14b Burn, Thomas, N., Lee, Kyutae, D., Dawany, N., Robertson, Tanner, F., Fisher, Megan, R., Bassing, Craig H., and Behrens, Edward M. : A Spontaneous Rag1 Nonsense Mutations Unveils Naturally Occurring N-truncated RAG1 Isoforms ImmunoHorizons 4: 119-128, 2020.

 2c
7 1d
2c back to top
26 Last updated: 09/05/2025
34 The Trustees of the University of Pennsylvania c
1f
27
24
 
1d
18
1 49 2 2 1a 32 34
19
12 12 1a 14