Angel M Varela-rohena,
Angel M Varela-Rohena
Education:
PhD (Immunology)
University of Pennsylvania, 2007.
PhD (Immunology)
University of Pennsylvania, 2007.
Post-Graduate Training
Penn-PORT Fellow, University of Pennsylvania, 2007-2009.
Permanent linkPenn-PORT Fellow, University of Pennsylvania, 2007-2009.
Selected Publications
Carpenito Carmine, Milone Michael C, Hassan Raffit, Simonet Jacqueline C, Lakhal Mehdi, Suhoski Megan M, Varela-Rohena Angel, Haines Kathleen M, Heitjan Daniel F, Albelda Steven M, Carroll Richard G, Riley James L, Pastan Ira, June Carl H: Control of large, established tumor xenografts with genetically retargeted human T cells containing CD28 and CD137 domains. Proceedings of the National Academy of Sciences of the United States of America 106(9): 3360-5, Mar 2009.Varela-Rohena Angel, Molloy Peter E, Dunn Steven M, Li Yi, Suhoski Megan M, Carroll Richard G, Milicic Anita, Mahon Tara, Sutton Deborah H, Laugel Bruno, Moysey Ruth, Cameron Brian J, Vuidepot Annelise, Purbhoo Marco A, Cole David K, Phillips Rodney E, June Carl H, Jakobsen Bent K, Sewell Andrew K, Riley James L: Control of HIV-1 immune escape by CD8 T cells expressing enhanced T-cell receptor. Nature medicine 14(12): 1390-5, Dec 2008.
Varela-Rohena Angel, Carpenito Carmine, Perez Elena E, Richardson Max, Parry Richard V, Milone Michael, Scholler John, Hao Xueli, Mexas Angela, Carroll Richard G, June Carl H, Riley James L: Genetic engineering of T cells for adoptive immunotherapy. Immunologic research 42(1-3): 166-81, 2008.
Suhoski Megan M, Golovina Tatiana N, Aqui Nicole A, Tai Victoria C, Varela-Rohena Angel, Milone Michael C, Carroll Richard G, Riley James L, June Carl H: Engineering artificial antigen-presenting cells to express a diverse array of co-stimulatory molecules. Molecular therapy : the journal of the American Society of Gene Therapy 15(5): 981-8, May 2007.
Martín-García Julio, Cao Wei, Varela-Rohena Angel, Plassmeyer Matthew L, González-Scarano Francisco: HIV-1 tropism for the central nervous system: Brain-derived envelope glycoproteins with lower CD4 dependence and reduced sensitivity to a fusion inhibitor. Virology 346(1): 169-79, Mar 2006.