Welcome to the Brady Lab
The Brady Lab is part of the Department of Cancer Biology and the Abramson Family Cancer Research Institute in the Perelman School of Medicine at the University of Pennsylvania. The research interests of our laboratory lie at the intersection of cancer biology, signal transduction, and metal homeostasis. Our lab seeks to unravel the complete framework of metal integration into kinase signaling networks to gain a better understanding of the contributions metals make to the tumorigenic process. Further, findings from these studies have the potential to be leveraged as a means to perturb metal availability to essential kinase signaling cascades in tumors.
Brady Lab postdoctoral fellows Yae-Jin Kim and Jessica Posimo, CAMB CB Ph.D. candidate Tiffany Tsang, and Penn Chemistry undergraduate researcher Gavin Bond worked together to describe a role for the Cu chaperone ATOX1 in BRAF-mutant melanoma in press at Metallomics. Congratulations team!
Brady Lab CAMB CB Ph.D. candidate Tiffany Tsang receives poster presentation award at the FASEB Summer Research Conference on Protein Kinases and Protein Phosphorylation: Mechanisms to Therapy in Palm Springs, CA for her work on investigating paradoxical YAP activation as an emergent limitation to Cu chelation therapy in BRAFV600E-driven melanoma. Congratulations!
Brady Lab CAMB CB Ph.D. candidate Tiffany Tsang receives National Cancer Institute NRSA Pre-doctoral Fellowship for her work on investigating paradoxical YAP activation as an emergent limitation to Cu chelation therapy in BRAFV600E-driven melanoma. Congratulations!
Department of Cancer Biology Events
Brady Presents at University of Minnesota Department of Biochemistry, Molecular Biology, and Biophysics Seminar Series.
April 3, 2019
CAMB CB Ph.D. and Brady Lab Member Tiffany Tsang Presents at CB Works in Progress.
March 15, 2019