Welcome to the Brady Lab
The Brady Lab is part of the Department of Cancer Biology and the Abramson Family Cancer Research Institute in the Perelman School of Medicine at the University of Pennsylvania. The research interests of our laboratory lie at the intersection of cancer biology, signal transduction, and metal homeostasis. Our lab seeks to unravel the complete framework of metal integration into kinase signaling networks to gain a better understanding of the contributions metals make to the tumorigenic process. Further, findings from these studies have the potential to be leveraged as a means to perturb metal availability to essential kinase signaling cascades in tumors.
Brady Lab adds new postdoctoral fellow Xingxing Gu. Xingxing received her B.S. in Agriculture from Hainan University and Ph.D. in Plant Biology from Shangai Institutes for Biological Sciences. Welcome Xingxing!
Brady Lab postdoctoral fellow Jessica Posimo and CAMB CB Ph.D. candidate Tiffany Tsang worked collaborated with members of the Chang Lab at University of California Berkeley to evaluate the utilization of a new activity-based ratiometric FRET probe to monitor labile Cu pools in the context of altered glutathione metabolism in press at PNAS. Congratulations team!
Brady Lab postdoctoral fellows Yae-Jin Kim and Jessica Posimo, CAMB CB Ph.D. candidate Tiffany Tsang, and Penn Chemistry undergraduate researcher Gavin Bond worked together to describe a role for the Cu chaperone ATOX1 in BRAF-mutant melanoma in press at Metallomics. Congratulations team!
Department of Cancer Biology Events
Tiffany Tsang Presents at Cancer Biology Open House Meeting for trainees sponsored by the Department of Cancer Biology.
December 20, 2019
Tiffany Tsang presented her collaborative work with Feldser lab on work in progress on "Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma".
CAMB CB Ph.D. and Brady Lab Member Tiffany Tsang Presents at CB Works in Progress.
October 15, 2019