Perelman School of Medicine at the University of Pennsylvania

Brady Lab

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NEWS

Brady Recipient of Penn Medicine Award of Excellence Michael S. Brown New Investigator Research Award

October 27, 2020

Presidential Termed Assistant Professor of Cancer Biology, Donita C. Brady is the recipient of this year’s Michael S. Brown New Investigator Research Award. Learn more here: https://www.med.upenn.edu/evpdeancommunications/2020-10-27-236.html 

Tsang Named 2020 Blavatnik Family Fellow in Biomedical Research

July 1, 2020

CAMB CB Ph.D. Candidate Tiffany Tsang receives 2020 Blavatnik Family Fellowship in Biomedical Research to support her Ph.D. training. 

Brady Delivers Virtual Seminar at Memorial Sloan Kettering Cancer Center Gerstner Sloan Kettering Graduate School  

April 8, 2020 

Donita Brady presents at Memorial Sloan Kettering Cancer Center Gerstner Sloan Kettering Graduate School hosted by Dean Michael Overholtzer

Brady Contributes to Copper Cancer Consortium at The Banbury Center at Cold Spring Harbor Laboratory 

March 2, 2020

Donita Brady presents at Copper Cancer Consortium at The Banbury Center at Cold Spring Habor Laboratory.  

Brady Lab Presents at COMET 

December 20, 2019

CAMB CB Ph.D. Candidate Tiffany Tsang presents her work on copper as an essential regulator of the autophagic kinase ULK1/2 to drive lung adenocarcinoma at Cancer Biology Open House Meeting (COMET) sponsored by the Department of Cancer Biology

Brady Presents at the University of Virginia Department of Microbiology, Immunology, and Cancer Biology   

December 5, 2019

Donita Brady presents at University of Virginia Department of Microbiology, Immunology, and Cancer Biology hosted by Kodi Ravichandran.   

Posimo Selected to Present at 1st Abramson Family Cancer Research Institute and Penn Cancer Research Postdoctoral Symposium 

November 19th, 2019

Brady Lab postdoctoral fellow Jessica Posimo will present her work copper as an essential regulator of the autophagic kinase ULK1/2 to drive lung adenocarcinoma at 1st annual Abramson Family Cancer Research Institute (AFCRI) and Penn Cancer Research Postdoctoral Symposium

Tsang Presents at CAMB Cancer Biology Work in Progress

October 15, 2019

CAMB CB Ph.D. Candidate Tiffany Tsang presents her work on copper as an essential regulator of the autophagic kinase ULK1/2 to drive lung adenocarcinoma at Work In Progress meeting. 

Brady Presents at the University of Dundee School of Life Science Symposium  

October 14, 2019

Donita Brady contributes to University of Dundee School of Life Science Symposium

Brady and Tsang Present at FASEB Summer Research Conference on Protein Kinases and Protein Phosphorylation 

July 7-12, 2019

Tiffany Tsang and Donita Brady contribute to the FASEB meeting on Protein Kinases and Protein Phosphorylation in Rancho Mirage, CA. Congratulations to Tiffany Tsang for being selected to give a short oral presentation on her work and for being selected for a poster presentation award! 

Posimo Presents at Penn Pancreatic Cancer Research Center Meeting

June 7th, 2019 

Brady Lab postdoctoral fellow Jessica Posimo will present her work copper as an essential regulator of the autophagic kinase ULK1/2 and lysosome function in pancreatic adenocarcinoma at Penn Pancreatic Cancer Research Center meeting. 

Tsang Presents at Penn Cancer Cell Metabolism Meeting

May 17th, 2019

CAMB CB Ph.D. Candidate Tiffany Tsang presents her work on copper as an essential regulator of the autophagic kinase ULK1/2 to drive lung adenocarcinoma at the Penn Cancer Cell Metabolism meeting. 

Brady Presents at the Oregon Health Sciences University Department of Physiology and Pharmacology Seminar Series 

May 9, 2019

Donita Brady contributes to Oregon Health Sciences University Department of Physiology and Pharmacology Seminar Series hosted by fellow Pew Biomedical Scholar Michael Cohen.   

Brady Presents at the University of Minnesota Department of Biochemistry, Molecular Biology, and Biophysics Seminar Series 

April 3, 2019

Donita Brady contributes to University of Minnesota Department of Biochemistry, Molecular Biology, and Biophysics Seminar Series hosted by fellow 2016 Pew Biomedical Scholar Wendy Gordon.   

Tsang Presents at CAMB Cancer Biology Work in Progress

March 15, 2019

CAMB CB Ph.D. Candidate Tiffany Tsang presents her work on countering paradoxical YAP activation in response to Cu chelation in BRAFV600E-driven melanoma at Work In Progress meeting. 

Brady Delivers Inaugural Lecture in Marie M. Daly Seminar Series at NYU Sackler Institute of Biomedical Graduate Studies

March 13, 2019

Donita Brady participates as an invited speaker in the inaugural Marie M. Daly Seminar Series at NYU Sackler Institute of Biomedical Graduate Studies

Brady Presents at The Broad Institute of MIT and Harvard University Innovators in Cancer Seminar Series 

February 15, 2019

Donita Brady contributes to The Broad Institute of MIT and Harvard University Innovators in Cancer Seminar Series hosted by Bill Sellers, Cory Johannessen, and Nicole Persky.  

Brady Presents at University of Cincinnati College of Medicine Department of Molecular Genetics, Biochemistry, and Microbiology Seminar Series

January 28, 2019

Donita Brady contributes to Department of Molecular Genetics, Biochemistry, and Microbiology Seminar Series at University of Cincinnati College of Medicine hosted by Katherine Vest

Brady Participates in Cell Symposium on Metabolites as Signaling Molecules 

December 11, 2018

Brady joins other Penn Perelman School of Medicine faculty members Celeste Simon, Katy Wellen, and Mitch Lazar in Seattle, WA for the Cell Symposium on Metabolites as Signaling Molecules

Brady Travels to Italy to Participate in the 11th International Copper Meeting

September 23-28, 2018

Brady contributes to science session on Copper in cellular differentiation, proliferation, and cancer at 11th International Copper Meeting in Sorrento, Italy. 

Yae-Jin Kim Joins the Brady Lab

September 1, 2018

Yae-Jin Kim joins the Brady Lab as a postdoctoral fellow. Prior to Penn, Yae-Jin completed her Ph.D. completed her Ph.D. in Molecular Science and Technology at Ajou University in the laboratory of Dr. Yong-Sung Kim. Welcome Yae-Jin! 

Brady Participates in Post-translational Regulation of Cell Signaling Meeting at Salk Institute 

July 31-August 3, 2018

Brady contributes to Post-Translational Regulation of Cell Signaling #20 at The Salk Institute

Brady Presents at Noreen O'Neill Melanoma Research Symposium at The Wistar Institute 

June 26, 2018

Brady joins others to participate in the Noreen O'Neill Melanoma Research Symposium hosted at The Wistar Institute to present on "New Molecular and Structural Insights into Copper-Modulated MAPK Signaling Essential for BRAFV600E Tumorigenesis".

Brady Lab Members Participate in the FASEB Cell Signaling in Cancer: from Mechanisms to Therapy 

June 3-8, 2018

Jessica Posimo, Tiffany Tsang, and Donita Brady contribute to the FASEB meeting on Cell Signaling in Cancer: from Mechanisms to Therapy in Steamboat Springs, CO. Congratulations to Tiffany Tsang for being selected to give a short oral presentation on her work and Jessica Posimo for being selected for a poster presentation award! 

 

Brady Lab Members Participate in the 11th Annual University of Pennsylvania Department of Cancer Biology Retreat 

May 29-31, 2018 

Caroline Davis, Julianne Davis, Jessica Posimo, and Tiffany Tsang presented their work at the 11th Annual University of Pennsylvania Department of Cancer Biology Retreat at Hyatt Regency Chesapeake Bay in Cambridge, MD.  Brady lab members found time to have fun and build on their teamwork in between scientific sessions and poster presentations.   

Brady Provides Keynote Address at University of Colorado Cancer Biology Program Postdoc Symposium  

May 18, 2018

Donita Brady will serve as a plenary speaker during the 2018 University of Colorado Cancer Biology Postdoc Symposium hosted by T32 supported postdoctoral fellows in Aurora, CO. 

Brady Participates in the 2018 V Foundation Scholar Summit 

April 24-25, 2018

Donita Brady will join fellow V Foundation Scholars at the 3rd Annual V Scholar Summit in Fairfax, VA to share the labs work on Targeting Autophagy in KRAS-Driven Pancreatic Cancer via Copper Reduction. 

Brady Presents at Drexel University College of Medicine Department of Biochemistry and Molecular Biology Seminar Series 

April 23, 2018

Donita Brady will contribute to the Biochemistry and Molecular Biology Seminar Series at the Drexel University College of Medicine hosted by Todd Strochlic

Brady Lab Presents at Penn Department of Biochemistry and Biophysics Friday Research Discussions 

March 9, 2018

Caroline Davis and Tiffany Tsang contribute to Biochemistry and Biophysics Friday Research Discussions to present their work in progress on "Examining copper conducted kinase signal transduction as a novel vulnerability in cancer". 

Brady Presents at Keystone Symposium on Tumor Metabolism 

January 22, 2018 

Donita Brady will speak during the Newcomers Workshop on January 22nd during the Keystone Symposium on Tumor Metabolism in Snowbird, UT. 

Brady Provides Keynote Address at Excellence in Diversity Symposium at Johns Hopkins University  

November 6, 2017

Donita Brady will serve as a plenary speaker during the 2017 Excellent in Diversity Symposium hosted by the Johns Hopkins University Diversity Postdoctoral Alliance Committee

Brady Chosen as 2018 Recipient of the Linda Pechenik Montague Investigator Award

November 2, 2017

Donita Brady was selected as the recipient of the 2018 Linda Pechenik Montague Investigator Award.  This award was created six years ago by philanthropist Linda Pechenik Montague to support the work of the most promising research faculty at the Perelman School of Medicine. The award will provide a total of $100,000 for the Brady lab to advance their research program. 

Brady Presents at the University of Pennsylvania Chemistry Department Biological Chemistry Seminar Series

November 2, 2017

Donita Brady will contribute to the Biological Chemistry Seminar Series in the Department of Chemistry at the University of Pennsylvania hosted by biology, chemistry, and biochemistry undergraduates. 

Brady Presents at Institute for Molecular Medicine Finland at the University of Helsinki Biomedicum Seminar Series 

October 23, 2017

Donita Brady will contribute to the Biomedicum Helsinki Seminar Series on the invitation of Gretchen Repasky and Krister Wennerberg of the Institute of Molecular Medicine Finland.   

Brady Lab Selected for a 2017 V Foundation Scholar Award 

October 4, 2017

The Brady Lab 2017 The V Foundation Scholar Award application was approved for funding to support studies to "Target Autophagy in KRAS-Driven Pancreatic Cancer via Copper Reduction". 

Congratulations to Jessica Posimo- American Cancer Society Postdoctoral Fellowship Awardee 

August 3, 2017 

Jessica Posimo, a postdoctoral fellow, has been awarded an American Cancer Society (ACS) Postdoctoral Fellowship to support her studies. Well done! 

Brady Lab Awarded National Institute of General Medicine Sciences Maximizing Investigators' Research Award for Early Stage Investigators (R35)

August 1, 2017 

Brady Lab has been awarded a NIGMS Maximizing Investigators' Research Award for Early Stage Investigators (R35) to support their studies for the next 5 years! 

Brady Lab Celebrates Postdoctoral Fellow Jessica Posimo's Wedding  

July 29, 2017

Postdoctoral fellow Jessica Posimo marries Michael Blenk at Kimpton Hotel Monaco Philadelphia! Congratulations Jessica! 

Brady Participates in the Gordon Research Conference Cell Biology of Metals 

July 23-28, 2017

Donita Brady will speak during the Metalloprotein Biogenesis and Signaling session on July 26th during the Gordon Research Conference Cell Biology of Metals in West Dover, VT at Grand Summit Resort Hotel on Mount Snow.   

Brady Lab Past and Present Members Graduate from the University of Puerto Rico at Mayaguez

July 15, 2017

Current University of Pennsylvania Post-Baccalaureate Research Education Program Scholar Gabriel Rodriquez Garcia and incoming University of Pennsylvania CAMB graduate group PhD candidate and former University of Pennsylvania Summer Undergraduate Internship Program Brady lab member Jaimarie Sostre Colon graduate from the University of Puerto Rico at Mayaguez with Bachelor of Science degrees in Industrial Biotechnology. Congratulations! 

Brady Lab Celebrates a Multitude of Achievements 

July 13, 2017

Brady lab members (Jessica Blanchard, Gabriel Rodriguez Garcia, Danielle Greenberg, Gavin Bond, Julianne Davis, Caroline Davis, Jessica Posimo, and Tiffany Tsang) get together at Jones to celebrate a multitude of achievements from successful completion of the 1st year of both undergraduate and PhD programs, passing qualifying examinations, admission to medical school, graduation from undergrad, an upcoming wedding, and beyond. Congrats to everyone! 

 

Brady Selected as 2017 William Guy Forbeck Research Foundation Scholar 

July 1, 2017

Donita Brady was selected along with 3 other early-career scientists as a 2017 Willam Guy Forbeck Research Foundation Scholar

Brady Lab Celebrates 2nd Year at the University of Pennsylvania Department of Cancer Biology 

July 1, 2017

Brady Lab Members Participate in the 10th Annual University of Pennsylvania Department of Cancer Biology Retreat 

June 26-28, 2017

Caroline Davis, Jessica Posimo, and Julianne Davis presented their work on  "Characterizing Copper as a Modulator of PKM2 Activity and Cellular Function in Hepatocellular Carcinoma", “Interplay between Cu availability and autophagy induction in pancreatic ductal adenocarcinoma”, and "Perturbations in Cu delivery to MAPK pathway components in BRAF-mutation positive melanoma" at the 10th Annual University of Pennsylvania Department of Cancer Biology Retreat at Mohonk Mountain House in New Paltz, NY.  Brady lab members found time to have fun and build on their teamwork in between scientific sessions and poster presentations.   

 

Brady Present at Johns Hopkins University School of Medicine Department of Physiology Seminar Series

April 26, 2017

Donita Brady will contribute to the Johns Hopkins University School of Medicine Department of Physiology Seminar Series on the invitation of Svetlana Lutsenko

Congratulations to Danielle Greenberg- Future Doctor of Osteopathic Medicine 

April 24, 2017

Danielle Greenberg, Brady lab Research Specialist, will matriculate as a medical student in the Fall of 2017 at the Philadelphia College of Osteopathic Medicine. Well done! 

Congratulations to Julianne Davis- 2017 NSF GRFP Awardee

March 17, 2017 

Julianne Davis, a second year CAMB Ph.D. candidate, has been awarded a NSF Graduate Research Fellowship to support her studies. Well done! 

Brady Participates in Pew Charitable Trust Annual Meeting 

March 5-10, 2017

Donita Brady will speak on March 7th during the Pew Scholars, Pew Fellows, and Pew-Stewart Annual Meeting in Santa Barbara, CA.   

Brady Presents at the Fox Chase Cancer Center Molecular Therapeutics Research Program Seminar Series

February 23, 2017

Donita Brady will contribute to the Fox Chase Cancer Center Molecular Therapeutics Research Program Seminar Series on the invitation of Erica Golemis

Brady Presents at Johns Hopkins University Bloomberg School of Public Health Biochemistry and Molecular Biology Seminar Series 

December 12, 2016

Donita Brady will contribute to the Johns Hopkins University Bloomberg School of Public Health Biochemistry and Molecular Biology Seminar Series on the invitation of current graduate student and postdoctoral fellows. 

Brady Co-Chairs Cancer Session at 10th International Copper Meeting

September 25-30, 2016

Donita Brady and Stephen Howell M.D. of UCSD will co-chair the Cancer Session on September 28th during the 10th International Copper Meeting in Sorrento, Italy. 

Brady Lab Attends Philadelphia Eagles Preseason Game

September 1, 2016

Brady Participates in the FASEB Protein Kinase Signaling Network Regulation

July 17-22, 2016

Donita Brady will speak during the Phosphorylation Signaling Networks session on July 20th during the FASEB Protein Kinase Signaling Network Regulation in Snowmass Village, CO.  

Brady Lab Attends Annual Ras Beach Retreat 

July 5-8, 2016

Brady lab members join the CampbellDer, and Cox labs of UNC, Counter, Fox, and Wood labs of Duke University at Annual RAS Beach Retreat in Emerald Isle, NC in July. 

Brady Lab Celebrates One Year Anniversary at Penn 

July 1, 2016

Brady Received JBC/Herb Tabor Young Investigator Award at FASEB Trace Elements in Biology and Medicine

June 9, 2016

Donita Brady was presented with the JBC/Herb Tabor Young Investigator Award at the FASEB Trace Elements in Biology Medicine meeting in Big Sky, MT.  The JBC/Hebert Tabor Young Investigator Award honors Tabor's invaluable contributions to JBC and to science as a whole.  The awards also recognize the innovators and achievers in new generations of researchers who exemplify Tabor's values of creativity and scientific excellence. 

Brady Selected as Pew Scholar in Biomedical Sciences

June 9, 2016

Donita Brady was selected along with 21 other exceptional early-career scientists as a Pew scholars in the biomedical sciences. The 2016 class of Pew biomedical scholars is drawn from prestigious institutions across the country, with each scholar receiving four years of flexible funding to pursue foundational, innovative research.

Brady Participates in the FASEB Trace Metal in Biology and Medicine Science Research Conference 

June 5-10, 2016

Donita Brady will speak during the Metals in Disease Session on June 5th during the FASEB Trace Elements in Biology and Medicine Science Research Conference in Big Sky, MT.  

Brady Contributes to Penn Perelman School of Medicine FOCUS on Health & Leadership for Women Lunchtime Seminar Series 

June 2, 2016

Making Every Penny Count in BRAF Mutation-Positive Melanoma- Targeting MEK½ Kinases. read more…

Brady Presents at the Temple University Fels Institute for Cancer Research and Molecular Biology Seminar Series

May 24, 2016  

Donita Brady will contribute to the Fels Institute for Cancer Research and Molecular Biology Seminar Series on the invitation of M. Raza Zaidi

Brady Lab Highlighted in Penn Medicine News Blog

December 16, 2015

"Brady looks for weak points in the protein signaling path of the RAS protein, which is mutated in 30 percent of cancers. She cells these metal-related chinks in the signaling chain 'novel vulnerabilities.'" read more...

Brady Provides Welcoming Remarks

August 5, 2015

Donita Brady provides welcoming remarks for the Penn 2015 Summer Undergraduate Internship Program Annual Research Symposium. read more...

Brady Interviewed for Science

July 10, 2015

Donita Brady interviewed for Science news on cancer’s copper connections. read more...

Brady Highlighted by Undergraduate Alma Mater

May 26, 2015

"As a member of the Highlanders' softball program from 2000-03, she found her passion for the sciences and health while an undergraduate at Radford. In her time donning the Red and White, Brady excelled as a chemistry major. After graduating, the 2003 Big South All-Academic Team member began her life long journey of learning and educating." read more...

Brady Interviewed for The Daily Pennsylvanian

April 15, 2015

" 'It’s truly an honor to be appointed as a Presidential Professor at the University of Pennsylvania,' Brady said in an email. 'I am enthusiastic about joining a group of scientifically innovative and collegial faculty within the Department of Cancer Biology and the larger community at Penn.' " read more...

Brady Appointed Presidential Professor at Penn

April 14, 2015

"Donita Brady has been named the seventh Presidential Professor at the University of Pennsylvania, effective July 1.  She will be Presidential Assistant Professor of Cancer Biology in Penn’s Perelman School of Medicine. The announcement was made today by Penn President Amy Gutmann and Provost Vincent Price." read more...