Penn Pancreatic Cancer Research Center

  • PCRC Team at PurpleStride November 4, 2017 (Kneeling in front row, PCRC Director Dr. Ben Z. Stanger and team captain Trish Gambino, RN)

  • Murine pancreatic tumor with cancer cells stained in green (YFP), nuclei in blue (DAPI) and collagen in purple - Captured by Nicole Aiello (Stanger Lab)

  • The PCRC Team at The Lustgarten Foundation walk November 6, 2016 in Pennsauken, NJ

  • Pancreatic tumor cells stained for YFP (cyan), E - Cadherin (red), Cytokeratin-19 (green), with nuclei counterstained with DAPI (blue) - Amine Sahmoud (Stanger Lab)

  • Pancreatic cancer cells dividing (light blue), 40x magnification - captured by David Bajor (Vonderheide Lab)

Welcome to the Penn Pancreatic Cancer Research Center!

The Penn Pancreatic Cancer Research Center (PCRC) is committed to delivering high-quality care for patients with pancreatic cancer. We take a multidisciplinary approach — integrating Medical Oncology, Surgery, Gastroenterology, Radiation Oncology, and Pathology — to deliver comprehensive and personalized options to our patients.

The American Cancer Society has reported that last year pancreatic cancer became the third leading cause of cancer death in the U.S., surpassing breast cancer (see Cancer Statistics). One encouraging piece of this report is that the five-year relative survival rate for pancreatic cancer has moved to 8 percent (from 5 percent several years ago). At the Penn Pancreatic Cancer Research Center (PCRC), we understand the urgent need to develop better treatments and cures for patients.

November Marks Pancreatic Cancer Awareness Month

As researchers and clinicians in the Penn PCRC, we honor survivors, patients, and caregivers and strive to offer Hope at All Stages.

News

PCRC Researchers have been featured in two articles in Let's Win! Pancreatic Cancer. Most recently, PCRC Oncologist Dr. Kim Reiss-Binder for her work on PARP inhibitors, and PCRC Director Dr. Ben Z. Stanger for his work on "hot" and "cold" tumors.

Research Advances

Shown below are four journal covers created by our researchers featuring recent work.

The laboratories of Erica Carpenter and David Issadore have been developing new ways of extracting molecular information about pancreatic tumors from the blood:

Work from the laboratories of Anil Rustgi and Ben Stanger shows how tumor plasticity (the ability of tumor cells to adopt new features) influences metastasis in pancreatic cancer:

Work from the laboratories of Robert Vonderheide and Ben Stanger probes the molecular wiring of tumors that renders them sensitive or resistant to immune therapies (Penn Press Release):

For more of our published research, see the Publications page: https://www.med.upenn.edu/pcrc/publications.html.

Information for clinical trials

We believe in the power of clinical trials in caring for patients and conquering this disease.
For more information, click here.

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