Members of the Brenner Bioengineering Lab

Jake Brenner, MD, PhD

Jake Brenner, MD, PhD

Assistant Professor and Attending Physician

Pulmonary, Allergy, & Critical Care Division, and
Systems Pharmacology & Translational Therapeutics Department
University of Pennsylvania

Jake's LinkedIn Profile

Jake's U Penn Faculty Bio

I spend 20% of my time attending in the ICU, and 80% developing technologies for pulmonary & critical care medicine. My bioengineering lab develops both nano-scale and macro-scale technologies. On the nano-scale, we are developing targeted drug delivery vehicles for acute critical illnesses, such as ARDS, sepsis, and stroke. On the macro-scale, our current projects focus on respiratory assist devices, most notably those around which we formed the company RightAir.

Laura Ferguson, MD, MS

Laura Ferguson, MD, MS

Pulm / Critical Care Fellow

Laura is a pulmonologist with a background in bioengineering.  In lab she works on next-generation RBC-hitchhiking of nanocarriers, ex vivo human lung studies of nanocarriers, and is interested in the development of nanomedicine for interstitital lung disease, her clinical sub-specialty.

Priyal Patel

Priyal Patel

Lab technician

Priyal designs and studies nanoparticles targeted to activated leukocytes, studies cell type distributions of nanocarriers in vivo, and work on our ex vivo human lung system for nanocarrier testing.  In August 2019, she will start podiatry school at Temple, and continue working with us to develop nanomedicine for peripheral artery disease.

Kate Rubey, MD

Kate Rubey, MD

Neonatology Fellow

Kate is a neonatology fellow at CHOP, working in the neonatal ICU (NICU), taking care of critically ill infants.  In lab she works on nanomedicine for severe infections, especially pneumonia, and setting up our ex vivo human lung imaging system.

Mike Zaleski

Mike Zaleski

Lab tech and project manager

Mike leads on project in collaboration with Insmed Corp to create a nanomedicine-based therapeutic for ARDS (acute respiratory distress syndrome).  Mike plans to apply to a PhD in bioengineering.

Marco Zamora

Marco Zamora

PhD Student

Marco is working on two projects.  The first is the development of a nanomedicine-based therapeutic for ARDS, in collaboration with Insmed Corp.  The second project involves how the innate immune system interacts with nanocarriers.