Welcome to the Bushman Lab

Our goal is to carry out research on interactions between humans and their microbes that yields the maximum positive effect on human welfare. Often this involves development and implementation of new technology for basic research and biotechnology. One research focus involves studies of the human microbiome, the gigantic community of microbes that live associated with every human. Other research centers on specific viruses, such as SARS-CoV-2 and HIV, and the full populations of viruses in humans—the virome. A third related area involves methods for understanding and improving approaches to human gene therapy, including integration by viral vectors.

 

Our laboratory supports a core facility that provides genomic analysis for human gene therapy, with particular focus on the consequences of gene modification for the human genome: Viral/ Molecular High Density Sequencing Core.

Check out the latest draft of  "Improving Your Scientific Writing", which contains a new chapter on interacting with Artificial Intelligence programs such as ChatGPT.

Bushman Lab on Bluesky

  • Wednesday, April 23, 2025

    Congrats to Marie Seleme, Aradhana Kasimsetty and the team on their report of effective methods for increasing expression from AAV vectors by blocking SUMOylation. Effective boosting by treatment with an inhibitor presently in use in humans! (PMID: 40263936)

  • Thursday, April 17, 2025

    The recent Conference on Retroviruses and Opportunistic Infections 2025 was a moving tribute to the importance of the HIV research field and efforts to eradicate HIV globally. Presentations are now up online. It was a great honor to deliver the Fields Lecture! https://www.croiwebcasts.org/console/player/54085?mediaType=slideVideo&

  • Saturday, April 12, 2025

    The misinformation from RFK Jr. around measles is shocking. Check out Rachel Maddow’s report. Vaccination beats magical thinking. https://www.youtube.com/watch?v=hJQUQJnUOI0