Cardiovascular Phenotyping Unit
The Cardiovascular Phenotyping Unit provides cardiac testing services with shared facilities for both children and adults. The Unit provides the technical services and expertise to conduct the highest quality research, provides research tests in a cost-effective manner, and provides unparalleled training opportunities in clinical research for investigators, fellows, students and technicians. Most services are provided across the life cycle. For studies involving both adult and pediatric populations, the pediatric and adult CPUs can collaborate closely and standardize procedures according to the investigators’ needs. Please contact the Directors for special arrangements or input regarding cardiovascular phenotyping.
Pediatric Unit
Vascular Laboratory Unit
- Brachial Artery Reactivity (BART)
- Carotid Intimal-Medi0al Thickness measurement (IMT)
- Pulse Wave Velocity evaluation
- Augmentation Index assessment
Electrocardiographic Laboratory Unit
- 12 lead electrocardiogram
Echocardiographic Laboratory Unit
- 2-dimensional imaging
- Color flow imaging
- Doppler imaging
- Tissue doppler imaging
- 3-dimensional imaging
- Non-invasive assessment of ventricular performance
Ambulatory Blood Pressure Monitoring Unit
- Ambulatory blood pressure monitor: Professional interpretation of test results
- Ambulatory blood pressure monitor: test
Pediatric Scientific Director:
Laura M. Mercer-Rosa, MD, MSCE
Email: mercerrosal@chop.edu
Adult Unit
- Resting ECG
- 2D Echocardiogram
- 3D Echocardiogram
- Echocardiogram quantitation and interpretation
- Stress echocardiography
- Stress echocardiography interpretation
- Stress ECG
- Stress ECG interpretation
- Tests of vascular structure/function, with prior approval
- Cardiopulmonary Exercise Testing (CPET), including VO2 measurements
- Cardiopulmonary Exercise Testing (CPET) + Echocardiography combined studies
- Treadmill or bike testing (Submaximal or Maximal), with ECG monitoring
This unit is located on the PPMC campus on the first floor of the Mutch Building.
Adult Scientific Directors:
Bonnie Ky, MD, MSCE (HUP)
Email: bonnie.ky@pennmedicine.upenn.edu
Benedicte Lefebvre, MD (HUP)
Email: Benedicte.Lefebvre@pennmedicine.upenn.edu
Paco E. Bravo, MD (Presby)
Email: Paco.Bravo@pennmedicine.upenn.edu