Research technique: Microperimetry, fixation and nystagmus


Research technique: Microperimetry, fixation, nystagmus, and evaluation of oculomotor control and instability (OCI)


18 Publications On Microperimetry, Fixation And Nystagmus

226. Kong X, Ibrahim-Ahmed M, Bittencourt MG, Strauss RW, Birch DG, CIDECIYAN AV, Ervin AM, Ho A, Sunness JS, Audo IS, Michaelides M, Zrenner E, Sadda S, Ip MS, West S, Scholl HPN; SMART Study Group. Longitudinal changes in scotopic and mesopic macular function as assessed with microperimetry in patients with Stargardt disease: SMART study report no. 2. American Journal of Ophthalmology, 236:32-44, 2022. [PubMed] [DOI]

225. Schönbach EM, Strauss RW, Cattaneo MEGV, Fujinami K, Birch DG, CIDECIYAN AV, Sunness JS, Zrenner E, Sadda SR, Scholl HPN. Longitudinal changes of fixation stability and location within 24 months in Stargardt disease: ProgStar Report No. 16. American Journal of Ophthalmology, 233:78-89, 2022. [PubMed] [DOI]

224. Krishnan AK, Roman AJ, Swider M, Jacobson SG, CIDECIYAN AV. Macular rod function in retinitis pigmentosa measured with scotopic microperimetry. Translational Vision Science & Techology, 10:3, 2021. [PubMed] [DOI]

219. CIDECIYAN AV, Jacobson SG, Ho AC, Garafalo AV, Roman AJ, Sumaroka A, Krishnan AK, Swider M, Schwartz MR, Girach A. Durable vision improvement after a single treatment with antisense oligonucleotide sepofarsen: a case report. Nature Medicine, 27:785-789, 2021. [PubMed] [DOI] [] [Penn Press Release]

209. Schönbach EM, Strauss RW, Ahmed MI, Janes JL, CIDECIYAN AV, Birch DG, Sunness JS, Zrenner E, Ip MS, Kong X, Sadda SR, Scholl HPN, for the ProgStar study group. The effect of attention on fixation stability during dynamic fixation testing in Stargardt disease. American Journal of Ophthalmology, 217:305-316, 2020. [PubMed]

208.  Schönbach EM, Strauss RW, Ibrahim MA, Janes JL, Birch DG, CIDECIYAN AV, Sunness JS, Muñoz B, Ip MS, Sadda SR, Scholl HPN, for the ProgStar study group. Faster sensitivity loss around dense scotomas than for overall macular sensitivity in Stargardt disease: ProgStar Report No. 14. American Journal of Ophthalmology, 216:219-225, 2020. [PubMed]

197. CIDECIYAN AV, Jacobson SG, Drack AV, Ho AC, Charng J, Garafalo AV, Roman AJ, Sumaroka A, Han IC, Hochstedler MD, Pfeifer WL, Sohn EH, Taiel M, Schwartz MR, Biasutto P, de Wit W, Cheetham ME, Adamson P, Rodman DM, Platenburg G, Tome MD, Balikova I, Nerinckx F, De Zaeytijd J, Van Cauwenbergh C, Leroy BP, Russell SR. Effect of an intravitreal antisense oligonucleotide on vision in Leber congenital amaurosis due to a photoreceptor cilium defect. Nature Medicine, 25:225-228, 2019. [PubMed] [Nat Med: News and Views] [] [UPenn Press Release] [ProQR Press Release] 

196. Sumaroka A, Garafalo AV, CIDECIYAN AV, Charng J, Roman AJ, Choi W, Saxena S, Aksianiuk V, Kohl S, Wissinger B, Jacobson SG. Blue cone monochromacy caused by the C203R missense mutation or large deletion mutations.Investigative Ophthalmology & Visual Science 59:5762-5772, 2018. [PubMed]

175. Jacobson SG, CIDECIYAN AV, Sumaroka A, Roman AJ, Charng J, Lu M, Choi W, Sheplock R, Swider M, Kosyk MS, Schwartz SB, Stone EM, Fishman GA. Outcome measures for clinical trials of Leber congenital amaurosis caused by the intronic mutation in the CEP290 gene. Investigative Ophthalmology & Visual Science 58:2609-2622, 2017. [PubMed]

170. Schönbach EM, Ibrahim MA, Strauss RW, Birch DG, CIDECIYAN AV, Hahn GA, Ho A, Kong X, Nasser F, Sunness JS, Zrenner E, Sadda SR, West SK, Scholl HPN, Progression of Stargardt Disease Study Group. Fixation location and stability using the MP-1 microperimeter in Stargardt disease: ProgStar Report No. 3. Ophthalmology Retina. 1:68-76, 2017.

161. CIDECIYAN AV, Roman AJ, Jacobson SG, Yan B, Pascolini M, Charng J, Pajaro S, Nirenberg S. Developing an outcome measure with high luminance for optogenetics treatment of severe retinal degenerations and for gene therapy of cone diseases. Investigative Ophthalmology & Visual Science 57:3211-3221, 2016. [PubMed]

147. Luo X, CIDECIYAN AV, Iannaccone A, Roman AJ, Ditta LC, Jennings BJ, Yatsenko SA, Sheplock R, Sumaroka A, Swider M, Schwartz SB, Wissinger B, Kohl S, Jacobson SG. Blue cone monochromacy: Visual function and efficacy outcome measures for clinical trials. PLoS One 10(4): e0125700, 2015. [PubMed] [PDF]

143. CIDECIYAN AV, Aguirre GK, Jacobson SG, Butt OH, Schwartz SB, Swider M, Roman AJ, Sadigh S, Hauswirth WW. Pseudo-fovea formation after gene therapy for RPE65-LCA. Investigative Ophthalmology & Visual Science 56:526-537, 2015. [PubMed]

124. CIDECIYAN AV, Swider M, Aleman TS, Feuer WJ, Schwartz SB, Russell RC, Steinberg JD, Stone EM, Jacobson SG. Macular function in macular degenerations: Repeatability of microperimetry as a potential outcome measure for ABCA4-associated retinopathy trials. Investigative Ophthalmology & Visual Science 53:841–852, 2012. [PubMed]

122. Jacobson SG, CIDECIYAN AV, Ratnakaram R, Heon E, Schwartz SB, Roman AJ, Peden MC, Aleman TS, Boye SL, Sumaroka A, Conlon TJ, Calcedo R, Pang J-J, ErgerKE, Olivares MB, Mullins CL, Swider M, Kaushal S, Feuer WJ, Iannaccone A, Fishman GA, Stone EM, Byrne BJ, Hauswirth WW. Gene therapy for Leber congenital amaurosis caused by RPE65 mutations: Safety and efficacy in fifteen children and adults followed up to three years. Archives of Ophthalmology 130:9-24, 2012.[PubMed]

104. CIDECIYAN AV, Hauswirth WW, Aleman TS, Kaushal S, Schwartz SB, Boye SL, Windsor EAM, Conlon TJ, Sumaroka A, Roman AJ, Byrne BJ, Jacobson SG. Vision 1 year after gene therapy for Leber’s congenital amaurosis. New England Journal of Medicine, 361:725-727, 2009. [PubMed] [Reprint] [Free Text in PubMed Central]

98. CIDECIYAN AV, Aleman TS, Boye SL, Schwartz SB, Kaushal S, Roman AJ, Pang J-j, Sumaroka A, Windsor EAM, Wilson JM, Flotte TR, Fishman GA, Heon E, Stone EM, Byrne BJ, Jacobson SG, Hauswirth WW. Human gene therapy for RPE65-isomerase deficiency activates the retinoid cycle of vision but with slow rod kinetics. Proceedings of the National Academy of Sciences USA, 105: 15112-15117, 2008. [PubMed] [PDF]

88. Jacobson SG, Aleman TS, CIDECIYAN AV, Heon E, Golczak M, Beltran WA, Sumaroka A, Schwartz SB, Windsor EAM, Wilson JM, Aguirre GD, Stone EM, Palczewski K. Human cone photoreceptor dependence on RPE65 isomerase. Proceedings of the National Academy of Sciences USA, 104:15123-15128, 2007. [PubMed] [PDF]

Last updated January 1, 2022