CATT Study Publications

  1. The CATT Research Group. Ranibizumab and bevacizumab for neovascular age-related macular degeneration. N Engl J Med 2011; 364:1897-908. Epub 2011 Apr 28. PMC3157322.
  2. The CATT Research Group. Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: 2-year results. Ophthalmology 2012; 119:1388–1398. Epub 2012 May 1. PMC3389193.
  3. Grunwald JE, Daniel E, Ying G-S, Pistilli M, Maguire MG, Alexander J, Whittock-Martin R, Parker CR, Sepielli K, Blodi BA, Martin DF, the CATT Research Group. Photographic assessment of baseline fundus morphologic features in the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology 2012. Epub 2012 Apr 17. PMC3401277.
  4. DeCroos FC, Toth CA, Stinnett SS, Heydary CS, Burns R, Jaffe GJ, for the CATT Research Group. Optical coherence tomography grading reproducibility during the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology 2012; 119:2549-57. Epub 2012 Aug 28. PMC3631582.
  5. Ying G-S, Huang J. Maguire MG, Jaffe GJ, Grunwald JE, Toth C, Daniel E, Klein M, Pieramici D, Wells J, Martin DF, the CATT Research Group. Baseline predictors for one-year visual outcomes with ranibizumab or bevacizumab for neovascular age-related macular degeneration. Ophthalmology 2013; 120:122-129. Epub 2012 Oct 6. PMC3536921.
  6. Hagstrom SA, Ying G-S, Pauer GJT, Sturgill-Short GM, Huang J, Callanan DG, Kim IK, Klein ML, Maguire MG, Martin DF, the Comparison of AMD Treatments Trials Research Group. Pharmacogenetics for genes associated with age-related macular degeneration in the Comparison of AMD Treatments Trials (CATT). Ophthalmology 2013; 120:593-9. Epub 2013 Jan 18. PMC 3633658.
  7. Jaffe GJ, Martin DF, Toth CA, Daniel E, Maguire MG, Ying G-S, Grunwald JE, Huang J, the CATT Research Group. Macular morphology and visual acuity in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2013; 120:1860-70. Epub 2013 May 03. PMC3737287.
  8. Maguire MG, Daniel E, Shah AR, Grunwald JE, Hagstrom SA, Avery RL, Huang J, Martin RW, Roth DB, Castellarin AA, Bakri SJ, Fine SL, Martin DF, the CATT Research Group. Incidence of choroidal neovascularization in the fellow eye in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 2013; 120:2033-41. Epub 2013 May 23. PMC3758381.
  9. Grunwald JE, Daniel E, Huang J, Ying G-S, Maguire MG, Toth CA, Jaffe GJ, Fine SL, Blodi B, Klein ML, Martin AA, Hagstrom SA, Martin DF, the CATT Research Group. Risk of geographic atrophy in Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 2014; 121:150-161. Epub 2013 Sep 30. PMC3892560.
  10. Daniel E, Toth CA, Grunwald JE, Jaffe GJ, Martin DF, Fine SL, Ying G-S, Huang J, Winter K, Hagstrom SA, Maguire MG, the CATT Research Group. Risk of scar in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2014; 121:656-66. Epub 2013 Dec 4. PMC3943618.
  11. Hagstrom SA, Ying G-S, Pauer GJT, Sturgill-Short GM, Huang J, Maguire MG, Martin DF. VEGFA and VEGFR2 gene polymorphisms and response to anti-vascular endothelial growth factor therapy in the Comparison of AMD Treatments Trials (CATT). JAMA Ophthalmology 2014; 132:521-7. Epub 2014 Mar 20.
  12. Kim BJ, Ying GS, Huang J, Levy N, Maguire MG, and the CATT Research Group. Sporadic visual acuity loss in the Comparison of AMD Treatments Trials (CATT). Am J Ophthalmol 2014; 158:128-135. Epub 2014 Apr 10.
  13. Folgar FA, Jaffe GJ, Ying G-S, Maguire MG, Toth CA, the CATT Research Group. Comparison of optical coherence tomography assessments in in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 2014;121:1956-1965. Epub 2014 May 15.
  14. Ying G-S, Kim BJ, Maguire MG, Huang J, Daniel E, Jaffe GJ, Grunwald JE, Blinder KJ, Flaxel CJ, Rahhal R, Regillo C, Martin DF, the CATT Research Group. Sustained Visual Acuity Loss in the Comparison of AMD Treatments Trials (CATT). JAMA Ophthalmology 2014;132:915-921. Epub 2014 May 29.
  15. Gewaily D, Grunwald JE, Pistilli M, Ying GS, Maguire MG, Daniel E, Ostroff CP, and the CATT Research Group. Delayed Patchy Choroidal Filling in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Am J Ophthalmol. Epub 2014 Jun 17.
  16. Lee JY, Folgar FA, Maguire MG, Ying GS, Toth CA, Martin DF, Jaffe GJ, the CATT Research Group. Outer Retinal Tubulation in the Comparison of Age-related Macular Degneration Treatments Trials (CATT). Ophthalmology. Epub 2014 July 23.
  17. Moja L, Lucenteforte E, Kwag K, Bertele V, Campomori A, Chakravarthy U, Dickersin K, Evans J, Kodjikian L, Lindsley K, Loke Y, Maguire M, Martin DF, Mugelli A, Reeves BC, Rogers CA, Schmucker C, Subramanian ML, D’Amico R, Virgili G. Systemic safety of bevacizumab versus ranibizumab for neovascular age-related macular degeneration: Cochrane Database Syst Rev. 2014 Sep 15;9:CD011230. [Collaborative Paper]
  18. Altaweel MM, Daniel E, Martin DF, Mittra RA, Grunwald JE, Lai MM, Melamud A, Morse LS, Huang J, Ferris FL, Fine SL, Maguire MG, the CATT Research Group. Outcomes of eyes with lesions composed of >50% blood in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology. Epub 2014 Oct 09.
  19. Grunwald JE, Pistilli M, Ying G-S, Maguire MG, Daniel E, Martin DF, the CATT Research Group. Growth of Geographic Atrophy in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2015;122:809-16. Epub 2014 Dec 24.
  20. Meredith TA, McCannel CA, Barr C, Doft B, Peskin E, Maguire MG, Martin DF, Prenner JL, Comparison of Age-Related Macular Degeneration Treatments Trials Research Group. Postinjection endophthalmitis in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2015;122:817-821. Epub 2015 Jan 15.
  21. Toth CA, DeCroos FC, Ying G-S, Stinnett SS, Heydary CS, Burns R, Maguire M, Martin DF, Jaffe GJ, the CATT Research Group. Identification of fluid on optical coherence tomography by treating ophthalmologists versus a reading center in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). Retina 2015; 35:1303–1314. Epub 2015 Feb 12.
  22. Ciulla TA, Ying G-S, Maguire MG, Martin DF, Jaffe GJ, Grunwald JE, Daniel E, Toth CA, the Comparison of Age-Related Macular Degeneration Treatments Trials Research Group. Influence of the vitreomacular interface on treatment outcomes in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 2015;122:1203-11. Epub 2015 Mar 28.
  23. Hagstrom SA, Ying G-S, Maguire MG, Martin DF, the CATT Research Group, Gibson J, Lotery A, Chakravarthy U, the IVAN Study Investigators. VEGFR2 gene polymorphisms and response to anti-vascular endothelial growth factor therapy in age-related macular degeneration. Ophthalmology 2015;122:1563-1568. Epub 2015 May 28.
  24. Willoughby AS, Ying G-S, Toth CA, Maguire MG, Burns RE, Grunwald JE, Daniel E, Jaffe GJ, the Comparison of Age-related Macular Degeneration Treatments Trials Research Group. Subretinal hyperreflective material in the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology 2015;122:1846-1853. Epub 2015 Jul 2.
  25. Ying G-S, Maguire MG, Daniel E, Ferris FL, Jaffe GJ, Grunwald JE, Toth C, Huang J, Martin DF, the CATT Research Group. Association of baseline characteristics and early vision response with two-year outcomes in the Comparison of AMD Treatments Trials. Ophthalmology Epub 2015 Sep 14.
  26. Daniel E, Shaffer J, Ying G-S, Grunwald JE, Martin DF, Jaffe GJ, Maguire MG, the the Comparison of AMD Treatments Trials (CATT) Research Group. Outcomes in eyes with retinal angiomatous proliferation in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2016;123:609-616. Epub 2015 Dec 8. PMC4766028.
  27. Shah N, Maguire MG, Martin DF, Shaffer J, Ying G-S, Grunwald JE, Toth CA, Jaffe GJ, Daniel E, the Comparison of Age-related Macular Degenertaion Treatments Trials Research Group. Angiographic cystoid macular edema and outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2016;123:858-64. Epub 2016 Jan 8. PMC4808340.
  28. Sharma S, Toth CA, Daniel E, Grunwald JE, Maguire MG, Ying G-S, Huang J, Martin DF, Jaffe GJ, the CATT Research Group. Macular morphology and visual acuity in the second year of the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2016;123:865-75. Epub 2016 Jan 9. PMC4998967.
  29. Zhou Q, Daniel E, Maguire MG, Grunwald JE, Martin ER, Martin DF, Ying G-S. Pseudodrusen and incidence of late age-related macular degeneration in fellow eyes in the Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology 2016;123:1530-40. Epub 2016 Apr 1. .
  30. Maguire MG, Ying GS, Jaffe GJ, Toth CA, Daniel E, Grunwald J, Martin DF, Hagstrom SA, the CATT Research Group. Single-nucleotide polymorphisms associated with age-related macular degenerationt and lesion phenotypes in the Comparison of Age-Related Macular Degeneration Treatments Trials. JAMA Ophthalmol 2016;134:674-681. Epub 2016 Apr 21. PMC5575967.
  31. Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group. Five-year outcomes with anti-vascular endothelial growth factor treatment of neovascular age-related macular degeneration: The Comparison of Age-Related Macular Degeneration Treatments Trials. Ophthalmology 2016;123:1751-61. Epub 2016 May 1. PMC4958614.
  32. Grunwald JE, Pistilli M, Daniel E, Ying GS, Pan W, Jaffe GJ, Toth CA, Hagstrom SA, Maguire MG, Martin DF, the CATT Research Group. Incidence and growth of geographic atrophy during 5 years of Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2017;124:97-104. Epub 2016 Oct 27. PMC5234734.
  33. Ferris FL III, Maguire MG, Glassman AR, Ying GS, Martin DF. Evaluating effects of switching anti- vascular endothelial growth factor drugs for age-related macular degeneration and diabetic macular edema. JAMA Ophthalmol 2017;135:145-149. Epub 2016 Dec 22. PMC5467458.
  34. Daniel E, Grunwald JE, Kim BJ, Maguire MG, Jaffe GJ, Toth CA, Ferris FL 3rd Martin DF, Shaffer J, Ying GS, the Comparison of Age-Related Degeneration Treatments Trials Research Group. Visual and morphological outcomes in eyes with hard exudates in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology Retina 2017;1:25-33. PMC5467458
  35. Zhou Q, Daniel E, Grunwald JE, Maguire MG, Gewaily D, Martin DF, Ying GS, the CATT Research Group. Association between pseudodrusen and delayed patchy choroidal filling in the comparison of age-related macular degeneration treatments trials. Acta Ophthal 2017;95:e518-520. Epub 2017 Mar 08. PMC5575967.
  36. Maguire MG, Shaffer J, Ying G-S Chakravarty U, Berg K, Bragadóttir R, Decullier E, Huot L, Kodjikian L, Martin DF, Reeves BC, Rogers CA, Schauwvlieghe AME, Schlingemann RO, the Bevacizumab-Ranibizumab International Trials Group. Serious adverse events with bevacizumab or ranibizumab for age-related macular degeneration: Meta-analysis of individual patient data. Ophthalmology Retina 2017 1:375-381. Epub 2017 Apr 13. PMC5640431
  37. Ying GS, Maguire MG, Pan W, Grunwald JE, Daniel E, Jaffe GJ, Toth CA, Hagstrom SA, Martin DF, the CATT Research Group. Baseline predictors for five-year visual acuity outcomes in the Comparison of AMD Treatments Trials. Ophthalmology Retina. Epub 2017 Nov 23.
  38. Toth CA, Tai V, Chiu SJ, Winter K, Sevilla M, Daniel E, Grunwald JE, Jaffe GJ, Martin DF, Ying GS, Pistilli M, Farsiu S, Maguire MG, the CATT Research Group.  Linking OCT, angiographic, and photographic lesion components in neovascular age-related macular degeneration.  Ophthalmology Retina 2018; 2:481-493. Epub 2017 Nov 28.
  39. Daniel E, Pan W, Ying G-S, Kim BJ, Grunwald JE, Ferris FL, Jaffe GJ, Toth CA, Martin DF, Fine SL, Maguire MG, the CATT Research Group. Development and course of scars in the Comparison of Age-related Macular Degenerations Treatments Trials (CATT). Ophthalmology. Epub 2018 Feb 14.
  40. Rahimy E, Ying G-S, Pan W, Hsu J, the CATT Research Group.  Effect of intraocular-lowering medications on neovascular age-related macular degeneration treatment outcomes in the Comparison of Age-related Macular Degeneration Treatment Trials. Retina 2018.  Epub 2018 Mar 5. PMC6123304
  41. Lin, LY. Qiang, Z. Hagstrom,S. Maguire, MG. Daniel, E. Grunwald,JE. Martin, DF. Ying,GS for the CATT Research Group. Association of Single-Nucleotide Polymorphisms in Age-Related Macular Degeneration with Pseudodrusen: Secondary Analysis of Data from the Comparison of AMD Treatments Trials. JAMA Ophthalmol. Published online 2018 May 3. doi:10.1001/ jamaophthalmol.2018.1231.
  42. Song D, Ying G-S, Dunaief JL, Bhuyan R, Li Y, Maguire MG, Grunwald JE, Daniel E, Hagstrom S, Martin DF, the CATT Research Group.  Association between oral iron supplementation and retinal or subretinal hemorrhage in the Comparison of Age-Related Macular Degeneration Treatments Trial.  Retina.  Epub 2018 Aug 28. PMC6462189.
  43. Jaffe GJ, Ying G-S, Toth CA, Daniel E, Grunwald JE, Martin DF, Maguire MG, the CATT Research Group. Macular morphology and visual acuity in year five of the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmology 2019;126:252-260. Epub 2018 Sep 3. PMC6462189.
  44. Daniel E, Ying G-S, Kim BJ, Toth CA, Ferris FL, Martin DF, Grunwald JE, Jaffe GJ, Dunaief JL, Pan W, Maguire MG, CATT Research Group. Five-year follow-up of non-fibrotic scars in the Comparison of Age-related Macular Degeneration Treatments Trials. Ophthalmology 2019;126:743-751. Epub 2018 Nov 23. PMC6475610.
  45. Toth CA, Tai V, Pistilli M, Chiu SJ, Winter K, Daniel E, Grunwald JE, Jaffe GJ, Martin DF, Ying G-S, Farsiu S, Maguire MG, the CATT Research Group.  Distribution of OCT features within areas of macular atrophy or scar after two years of anti-VEGF treatment for neovascular AMD in CATT. Ophthalmology Retina 2019;3:316-325. Epub 2018 Dec 3. PMC6482846.
  46. Bavinger JC, Ying G-S, Daniel E, Grunwald JE, Maguire MG, the Comparison of Age-Related Macular Degeneration Treatments Trials Research Group. The relationship between cilio-retinal arteries and advanced age-related macular degeneration in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). JAMA Ophthalmol 2019;137:1306-1311. Epub 2019 Sep 12.  PMC6743058.
  47. Scoles D, Ying G-S, Pan W, Hua P, Grunwald JE, Daniel E, Jaffe GJ, Toth CA, Martin DF, Maguire MG, the Comparison of AMD Treatments Trials Research Group.  Characteristics of eyes with good visual acuity at 5 years after initiation of treatment for age-related macular degeneration by not receiving treatment from years 3 to 5. Post hoc analysis of the CATT Randomized Clinical Trial. JAMA Ophthalmol 2020;138:276-284. Epub 2020 Jan 30. PMC7042910.
  48. Daniel E, Maguire MG, Grunwald JE, Toth CA, Jaffe GJ, Martin DF, Ying G-S, the Comparison of Age-Related Macular Degeneration Treatments Trials Research Group.  Incidence and progression of non-geographic atrophy in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). JAMA Ophthalmol. 2020;138:510-518.
  49. Evans RN, Reeves BC, Maguire MG, Martin D, Muldrew A, Peto T, Rogers C, Chakravarthy U. Associations of Variation in Retinal Thickness With Visual Acuity and Anatomic Outcomes in Eyes With Neovascular Age-Related Macular Degeneration Lesions Treated With Anti-Vascular Endothelial Growth Factor Agents. JAMA Ophthalmol. 2020;138:1043-1051.
  50. Kolomeyer AM, Smith E, Daniel E, Ying G-S, Pan W, Maguire MG, Kim BJ, the CATT Research Group. Beta peripapillary atrophy and geographic atrophy in the Comparison of Age-related Macular Degeneration Treatments Trials. Retina 2021;41:125-134.
  51. Finn AP, Pistilli M, Tai V, Daniel E, Ying G-S, Maguire MG, Grunwald JE, Martin DF, Jaffe GJ, Toth CA, the Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group. Localized optical coherence tomography (OCT) baseline precursors of geographic atrophy and fibrotic scar at years 2 and 5 in the Comparison of Age-Related Macular Degeneration Treatments Trials. Am J Ophthalmol. 2021;223:338-347.
  52. Song D, Hua P, VanderBeek B, Dunaief JL, Grunwald JE, Daniel E, Maguire MG, Martin DF, Ying G-S. Systemic medication use and the incidence of geographic atrophy in the Comparison of Age-related Macular Degeneration Treatment Trials (CATT).  Retina 2021;41:1455-1462.
  53. Core JQ, Pistilli M, Daniel E, Grunwald JE, Toth CA, Jaffe GJ, Hua P, Martin DF, Ying GS, Maguire MG; Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group. Predominantly Persistent Subretinal Fluid in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). Ophthalmol Retina. 2021 Jun 11:S2468-6530(21)00192-5. doi: 10.1016/j.oret.2021.06.003. Online ahead of print.