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CSI Initiative
The Chronobiology and Sleep Institute (CSI) seeks to support research initiatives that expand the scope of investigation in the areas of circadian rhythms and sleep. We are particularly interested in innovative projects that use cross-disciplinary approaches and have the potential to provide technological or conceptual breakthroughs. Large collaborative projects may request up to $100k per year, not including faculty salary. Smaller projects will also be considered, with budgets scaled appropriately. A second year of funding will be contingent upon demonstrated progress the first year. Awardees will present their projects at research meetings of the CSI.
Applications should include a research proposal of no more than 3 pages, an NIH biosketch for each participating PI, and a detailed budget with justification. Please send applications to Jackie Fowlkes (jfowlkes@pennmedicine.upenn.edu) by March 15th. Anticipated start date for funding is June 1, 2020.*
*Due to fiscal circumstance caused by the COVID-19 pandemic, this initiative was suspended.
Software Packages for Circadian/Sleep Analysis
Clocklab is a package for data collection and analysis of circadian behavior.
Drosophila Activity Monitoring System including infra-red monitors for raw data collection and filescan program for downstream data analysis.
JTK Cycle is a non-parametric algorithm for identification of cycling variables in large data sets.
MetaCycle Provides two functions-meta2d and meta3d for detecting rhythmic signals from time-series datasets.
Pysolo is a package for Drosophila sleep analysis.
ActogramJ is an ImageJ Plug-in for circadian rhythm analysis.
Databases of Sleep/Circadian Genes
CircadianServer Effects of feeding on rhythmic transcripts in the mouse liver.
A mouse sleep database, from Diessler, S. et al. PLoS Biol 16, e2005750 (2018)