PUBLICATIONS
137. Single-atom substitution redirects KatG reactivity from cofactor biogenesis to stereoselective sulfoxidation
Duan R, Li J, Griffith WP, Xu Y, Burrows ND, Green AP, and Liu A*
Nat. Commun., 2026, 17:5309 (DOI: 10.1038/s41467-026-73579-y)
136. Substrate analogs implicate a free radical pathway in tyrosine hydroxylase catalysis
Traore ES, Wang Y, Griffith WP, and Liu A*
ACS Catalysis, 2025, 15, 18270-18281 (DOI: 10.1021/acscatal.5c05776)
135. Structural and spectroscopic resolution of the NADPH redox state in the STEAP2 cytosolic oxidoreductase domain
Shin I, Sun L.-Z.,* and Liu A*
J. Biol. Chem., 2025, 301(12), 110822 (1 - 7) (DOI: 10.1016/j.jbc.2025.110822)
134. Hydralazine inhibits cysteamine dioxygenase to treat preeclampsia and senesce glioblastoma
Shishikura K, Li J, Chen Y, McKnight NR, Keeley TP, Bustin KA, Barr EW, Chilkamari SR, Ayub M, Kim SW, Lin Z, Hu RM, Hicks K, Wang X, O’Rourke DM, Bollinger JM Jr, Binder ZA, Parsons WH, Martemyanov KA, Liu A, and Matthews ML*
Sci. Adv., 2025, 11(42), eadx7687 (1 - 17) (DOI: 10.1126/sciadv.adx7687)
133. Deciphering tryptophan oxygenation: Key modulators of 2-oxindole formation in MarE
Nguyen RC, Shin I*, and Liu A*
Angew. Chem. Int. Ed., 2025, 64(35), e202510848 (1 - 7) (DOI: 10.1002/anie.202510848) 
Narrator: Romie Nguyen
132. Robust error calibration for serial crystallography
Mittan-Moreau DW*, Oklejas V, Paley DW, Bhowmick A, Nguyen RC, Liu A, Kern J, Sauter NK, Brewster AS
Acta Crystallogr. D: Struct. Biol., 2025, 81(5), 265-275 (DOI: 10.1107/S2059798325002852)
131. Protein-derived cofactors: Chemical innovations expanding enzyme catalysis
Graciano A and Liu A*
Chem. Soc. Rev., 2025, 54(9), 4502 - 4530 (DOI: 10.1039/d4cs00981a)
130. Structural insights into 2-oxindole-forming monooxygenase MarE: Divergent architecture and substrate positioning versus tryptophan dioxygenases
Shin I, Nguyen RC, Montoya SR, and Liu A*
J. Biol. Chem., 2025, 301(3), 108241 (1-14) (DOI: 10.1016/j.jbc.2025.108241)
129. Catalase-peroxidase (KatG): A potential frontier in tuberculosis drug development
Liu A*
Crit. Rev. Biochem. Mol. Biol., 2024, 59(6), 434-446 (DOI: 10.1080/10409238.2025.2470630)
128. α-Amino-β-carboxymuconate-ε-semialdehyde decarboxylase catalyzes enol/keto tautomerization of oxaloacetate
Yang Y*, Davis I, Altman RA, and Liu A*
J. Biol. Chem., 2024, 300(11), 107878 (1-11) (DOI: 10.1016/j.jbc.2024.107878)
127. Indole-N-linked hydroperoxyl adduct of protein-derived cofactor modulating catalase-peroxidase functions
Li J, Duan R, Traore ES, Davis I, Nguyen RC, Griffith WP, Goodwin DC, Jarzecki AA, and Liu A*
Angew. Chem. Int. Ed., 2024, 63(49), e202407018 (1-10) (DOI: 10.1002/anie.202407018)
126. Cobalt(II)-substituted cysteamine dioxygenase oxygenation proceeds through a cobalt(III)-superoxo complex
Li J*, Duan R, and Liu A*
J. Am. Chem. Soc., 2024, 146(27), 18292–18297 (DOI: 10.1021/jacs.4c01871)
125. Unveiling the mechanism of cysteamine dioxygenase: A combined HPLC-MS assay and metal-substitution approach
Duan R, Li J, and Liu A*
Methods Enzymol. 2024, 703, 147-166 (DOI: 10.1016/bs.mie.2024.05.018)
124. In situ structural observation of a substrate- and peroxide-bound high-spin ferric-hydroperoxo intermediate in P450 enzyme CYP121
Nguyen RC, Davis I, Dasgupta M, Wang Y, Simon P, Butryn A, Makita H, Bogacz I, Dornevil K, Aller P, Bhowmick A, Chatterjee R, Kim I-S, Zhou T, Mendez D,
Paley, D, Fuller F, Alonso Mori R, Batyuk A, Sauter N, Brewster A, Orville AM, Yachandra V, Yano J, Kern J,* and Liu A*
J. Am. Chem. Soc., 2023, 145(46), 25120-25133 (DOI: 10.1021/jacs.3c04991)
123. Structural and spectroscopic characterization of RufO indicates a new biological role in rufomycin biosynthesis
Jordan S, Li B, Traore ES, Wu Y, Usai R, Liu A, Xie Z-R, Wang Y*
J. Biol. Chem. 2023, 299, 105049 (DOI: 10.1016/j.jbc.2023.105049)
122. Simultaneous separation and detection of nine kynurenine pathway metabolites by reversed-phase liquid chromatography-mass spectrometry: Quantitation of inflammation in human cerebrospinal fluid and plasma
Patel VD, Shamsi SA*, Miller A, Liu A, and Powell M
Anal. Chim. Acta, 2023, 1278, 341659 (DOI: 10.1016/j.aca.2023.341659)
121. Structural insights into the half-of-sites reactivity in homodimeric and homotetrameric metalloenzymes
Nguyen RC, Stagliano C, and Liu A*
Curr. Opin. Chem. Biol., 2023, 75:102332 (1-9) (DOI: 10.1016/j.cbpa.2023.102332)
120. Kynurenine pathway regulation at its critical junctions with fluctuation of tryptophan
Newton A, McCann L, Huo L, and Liu A*
Metabolites, 2023, 13, 500 (DOI: 10.3390/metabo13040500)
119. Quantitation of tryptophan and kynurenine in human plasma using 4-vinylphenylboronic acid column by capillary electrochromatography coupled with mass spectrometry
Patel VD, Shamsi SA*, Miller A, and Liu A
Electrophoresis, 2023, 44, 529-539 (DOI: 10.1002/elps.202200251)
118. Charge maintenance during catalysis in non-heme iron oxygenases
Traore ES and Liu A*
ACS Catalysis, 2022, 12(10), 6191-6208 (DOI: 10.1021/acscatal.1c04770)
117. Probing extradiol dioxygenase mechanism in NAD+ biosynthesis by viewing reaction cycle intermediates
Davis I and Liu A*
Encyclopedia of Inorganic and Bioinorganic Chemistry (EIBC), 2022, 1-8 (DOI: 10.1002/9781119951438.eibc2813)
116. Metalloenzymes involved in carotenoid biosynthesis in plants
Davis I*, Geng J, and Liu A*
Methods Enzymol., 2022, 671, 207-222 (DOI: 10.1016/bs.mie.2022.01.012)
115. A new regime of heme-dependent aromatic oxygenase superfamily
Shin I, Wang Y, and Liu A*
Proc. Natl. Acad. Sci. U.S.A., 2021, 118(43), e210656 (1-10) (DOI: 10.1073/pnas.2106561118) 
114. Crystal structure of human cysteamine dioxygenase provides a structural rationale for its function as an oxygen sensor
Wang Y, Shin I, Li J, and Liu A*
J. Biol. Chem., 2021, 297(4), 101176 (1-10) (DOI: 10.1016/j.jbc.2021.101176) 
Narrator: Yifan (Amber) Wang
113. HygY is a twitch radical SAM epimerase with latent dehydrogenase activity revealed upon mutation of a single cysteine residue
Besandre R, Chen Z, Davis I, Zhang J, Ruszczycky M, Liu A, and Liu H-w*
J. Am. Chem. Soc., 2021, 143(37), 15152–15158 (DOI: 10.1021/jacs.1c05727)
112. Capillary electrochromatography-mass spectrometry of kynurenine pathway metabolites
Chawdhury A, Shamsi SA*, Miller A, and Liu A
J. Chromatogr. A., 2021, 1651, 462294 (1-14) (DOI: 10.1016/j.chroma.2021.462294)
111. Molecular rationale for partitioning between C-H and C-F bond activation in heme-dependent tyrosine hydroxylase
Wang Y, Davis I, Shin I, Xu H, and Liu A*
J. Am. Chem. Soc., 2021, 143(12), 4680-4693 (DOI: 10.1021/jacs.1c00175) 
Narrator: Yifan (Amber) Wang
MP4, 8'52"
110. A novel catalytic heme cofactor in SfmD with a single thioether bond and a bis-His ligand set revealed by de novo crystal structural and spectroscopic study
Shin I, Davis I, Nieves-Merced K, Wang Y, McHardy S, and Liu A*
Chem. Sci., 2021, 12(11), 3984-3998 (Edge Article) (DOI: 10.1039/D0SC06369J) 
Inchul Shin
(MP4, 13'24")
109. Heme binding to HupZ with a C-terminal tag from Group A Streptococcus
Traore ES, Li J, Chiura T, Geng J, Sachla A, Yoshimoto F, Eichenbaum Z, Davis I, Max P*, and Liu A*
Molecules, 2021, 26(3), 549 (1-19) (DOI: 10.3390/molecules26030549) 
Narrator: Ephrahime S. Traore
(LiveSlides: pending)
108. Diflunisal derivatives as modulators of ACMS decarboxylase targeting the tryptophan-kynurenine pathway
Yang Y, Borel T, de Azambuja F, Johnson D, Sorrentino JP, Udokwu C, Davis I, Liu A*, and Altman RA*
J. Med. Chem., 2021, 64(1), 797–811 (DOI: 10.1021/acs.jmedchem.0c01762) 
107. Formation of monofluorinated radical cofactor in galactose oxidase through copper-mediated C−F bond scission
Li J, Davis I, Griffith WP, and Liu A*
J. Am. Chem. Soc., 2020, 142(44), 18753-18757 (DOI: 10.1021/jacs.0c08992) 
Narrator: Jiasong Li
(MP4, 7'39")
106. Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens
Wang Y, Liu KF, Yang Y, Davis I, and Liu A*
Proc. Natl. Acad. Sci. U.S.A., 2020, 117(33) 19720-19730 (PNAS Direct Submission) (DOI: 10.1073/pnas.2005327117) 
Narrators: Yifan Wang & Ian Davis
105. Characterization of the non-heme iron center of cysteamine dioxygenase and its interaction with substrates
Wang Y, Davis I, Yang Y, Chen Y, Naik SG, Griffith WP, and Liu A*
J. Biol. Chem., 2020, 295(33), 11789-11802 (DOI: 10.1074/jbc.RA120.013915) 
Narrator: Yifan Wang
104. Kinetic and spectroscopic characterization of the catalytic ternary complex of tryptophan 2,3-dioxygenase
Geng J, Weitz AC, Dornevil K, Hendrich MP, and Liu A*
Biochemistry, 2020, 59(30), 2813-2822 (DOI: 10.1021/acs.biochem.0c00179)
103. Carbon-fluorine bond cleavage mediated by metalloenzymes
Wang Y and Liu A*
Chem. Soc. Rev., 2020, 49(14), 4906-4925 (DOI: 10.1039/C9CS00740G)
102. Substrate-assisted hydroxylation and O-demethylation in the peroxidase-like cytochrome P450 enzyme CYP121
Nguyen RC, Yang Y, Wang Y, Davis I, and Liu A*
ACS Catalysis, 2020, 10(2), 1628-1639 (DOI: 10.1021/acscatal.9b04596) 
Narrator: Romie C. Nguyen
101. Crystal structures of L-DOPA dioxygenase from Streptomyces sclerotialus
Wang Y, Shin I, Fu Y, Colabroy KL*, and Liu A*
Biochemistry, 2019, 58(52), 5339-5350 (DOI: 10.1021/acs.biochem.9b00396)
(invited original contribution for a special issue “Current Topics in Mechanistic Enzymology 2019”)
Narrators: Yifan Wang & Inchul Shin
100. Quaternary structure of α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD) controls its activity
Yang Y, Davis I, Matsui T, Rubalcava I, and Liu A*
J. Biol. Chem., 2019, 294(30), 11609-11621 (DOI: 10.1074/jbc.RA119.009035) (LiveSlide video presentation) featured as a JBC cover story
99. Biocatalytic carbon-hydrogen and carbon-fluorine bond cleavage through hydroxylation promoted by a histidyl-ligated heme enzyme
Wang Y, Davis I, Shin I, Wherritt DJ, Griffith WP, Dornevil K, Colabroy KL, and Liu A*
ACS Catalysis, 2019, 9(6), 4764-4776 (DOI: 10.1021/acscatal.9b00231) featured as an ACS Editors’ Choice article
Narrators: Yifan Wang and Ian Davis
(Short version published by ACS: 8 slides)
98. Probing the Cys-Tyr cofactor biogenesis in cysteine dioxygenase by the genetic incorporation of fluorotyrosine
Li J, Koto, T, Davis I, and Liu A*
Biochemistry, 2019, 58(17), 2218-2227 (DOI: 10.1021/acs.biochem.9b00006) featured as an alternate ACS Biochemistry cover story
97. Cleavage of a carbon–fluorine bond by an engineered cysteine dioxygenase
Li J, Griffith WP, Davis I, Shin I, Wang J, Li F, Wang Y, Wherritt D, and Liu A*
Nat. Chem. Biol., 2018, 14(9), 853-860 (DOI: 10.1038/s41589-018-0085-5)
96. Backbone dehydrogenation in pyrrole-based pincer ligands
Krishnan VM, Davis I, Baker TM, Curran DJ, Arman H, Neidig ML, Liu A, and Tonzetich ZJ*
Inorg. Chem. 2018, 57(15), 9544-9553 (DOI: 10.1021/acs.inorgchem.8b01643)
95. Adapting to oxygen: 3-Hydroxyanthranilate 3,4-dioxygenase employs loop dynamics to accommodate two substrates with disparate polarities
Yang Y, Liu F*, and Liu A*
J. Biol. Chem., 2018, 293(27), 293, 10415-10424 (DOI: 10.1074/jbc.RA118.002698) featured as a JBC cover story
94. Cofactor biogenesis in cysteamine dioxygenase: C-F bond cleavage with genetically incorporated unnatural tyrosine
Wang Y, Griffith WP, Li J, Koto T, Wherritt D, Fritz E, and Liu A*
Angew. Chem. Int. Ed., 2018, 57(27), 8149-8153 (DOI: 10.1002/ange.201803907 & 10.1002/anie.201803907)
93. Reassignment of the human aldehyde dehydrogenase ALDH8A1 (ALDH12) to the kynurenine pathway in tryptophan catabolism
Davis I, Yang Y, Wherritt D, and Liu A*
J. Biol. Chem., 2018, 293(25), 9594-9603 (DOI: 10.1074/jbc.RA118.003320)
92. Stepwise O-atom transfer in heme-based tryptophan dioxygenase: Role of substrate ammonium in epoxide ring opening
Shin I, Ambler BR, Wherritt DJ, Griffith WP, Maldonado AC, Altman RA, and Liu A*
J. Am. Chem. Soc., 2018, 140(12), 4372-4379 (DOI: 10.1021/jacs.8b00262)
91. High-frequency/high-field EPR and theoretical studies of tryptophan-based radicals
Davis I, Koto T, Terrell JR, Kozhanov A, Krzystek J, and Liu A*
J. Phys. Chem. A, 2018, 122(12), 3170-3176 (DOI: 10.1021/acs.jpca.7b12434)
90. Radical trapping study of the relaxation of bis-Fe(IV) MauG
Davis I, Koto T, and Liu A*
Reactive Oxygen Species, 2018, 5(13), 46-55 (DOI: 10.20455/ros.2018.801)
89. Probing ligand exchange in the P450 enzyme CYP121 from Mycobacterium tuberculosis:
Dynamic equilibrium of the distal heme ligand as a function of pH and temperature
Fielding AJ, Dornevil K, Ma L, Davis I, and Liu A*
J. Am. Chem. Soc., 2017, 139(48), 17484-17499 (DOI: 10.1021/jacs.7b08911)
88. Mutual synergy between catalase and peroxidase activities of the bifunctional enzyme KatG is facilitated by electron-hole hopping within the enzyme
Njuma OJ, Davis I, Ndontsa EN, Krewall JR, Liu A, and Goodwin DC*
J. Biol. Chem., 2017, 292(45), 18408-18421 (DOI: 10.1074/jbc.M117.791202)
87. Cross-linking of dicyclotyrosine by the cytochrome P450 enzyme CYP121 from Mycobacterium tuberculosis proceeds through a catalytic shunt pathway
Dornevil K, Davis I, Fielding AJ, Terrell JR, Ma L, and Liu A*
J. Biol. Chem., 2017, 292(33), 13645-13657 (DOI: 10.1074/jbc.M117.794099)
86. Hypertryptophanemia due to tryptophan 2,3-dioxygenase deficiency
Ferreira F,* Shin I, Sosova I, Dornevil K, Jain Shailly, Dewey D, Liu F, and Liu A*
Mol. Genet. Metab., 2017, 120(4), 317-324 (DOI: 10.1016/j.ymgme.2017.02.009)
85. Oxygen activation by mononuclear nonheme iron dioxygenases involved in the degradation of aromatics
Wang Y, Li J, and Liu A*
J. Biol. Inorg. Chem., 2017, 22(2), 395-405 (DOI: 10.1007/s00775-017-1436-5)
(invited article for a special issue of the journal under the theme of 60 Years of Oxygen Activation)
84. Heterolytic O-O bond cleavage: Functional role of Glu113 during bis-Fe(IV) formation in MauG
Geng J, Huo L, and Liu A*
J. Inorg. Biochem., 2017, 167, 60-67 (DOI: 10.1016/j.jinorgbio.2016.11.013)
83. A pitcher-and-catcher mechanism drives endogenous substrate isomerization by a dehydrogenase in kynurenine metabolism
Yang Y, Davis I, Ha U, Wang Y, Shin I, and Liu A*
J. Biol. Chem., 2016, 291(51), 26252-26261 (DOI: 10.1074/jbc.M116.759712)
(featured as "Papers of the Week and selected, after publication, in a collection of Enzymology virtual issue)
82. Control of carotenoid biosynthesis through a heme-based cis-trans isomerase
Beltrán J, Kloss B, Hosler JP, Geng J, Liu A, Modi A, Dawson JH, Sono M, Shumskaya M, Ampomah-Dwamena C, Love JD, and Wurtzel ET*
Nat. Chem. Biol., 2015, 11(8), 598-605 (DOI: 10.1038/nchembio.1840)
81. What is the tryptophan kynurenine pathway and why is it important to neurotherapeutics? (Invited Editorial)
Davis I and Liu A*
Expert Review of Neurotherapeutics, 2015, 15(7), 719-721 (DOI: 10.1586/14737175.2015.1049999)
80. An iron reservoir to the catalytic metal: The rubredoxin iron in an extradiol dioxygenase
Liu F, Geng J, Gumpper RH, Barman A, Davis I, Ozarowski A, Hamelberg D, and Liu A*
J. Biol. Chem., 2015, 290(25), 15621-15634 (DOI: 10.1074/jbc.M115.650259)
79. Probing bis-Fe(IV) MauG: Experimental evidence for the long-range charge-resonance model
Geng J, Davis I, and Liu A*
Angew. Chem. Int. Ed., 2015, 54, 3692-3696 (DOI: 10.1002/ange.201410247 & 10.1002/anie.201410247)
(This paper provides further experimental evidence supporting the biological Charge Resonance stabilization phenomenon described in our manuscript #71).
78. Crystallographic and spectroscopic snapshots reveal a dehydrogenase in action
Huo L, Davis I, Liu F, Andi B, Esaki S, Hiroaki I, Li T, Hasegawa Y, Orville AM, and Liu A*
Nat. Commun., 2015, 6:5935 (1-10) (DOI: 10.1038/ncomms6935)
(This article defines the structure of a kynurenine pathway dehydrogenase and a sp3-to-sp2 transition during catalysis)
77. Human α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase (ACMSD): A structural and mechanistic unveiling
Huo L, Liu F, Hiroaki I, Li T, Hasegawa Y, and Liu A*
Proteins, 2015, 83(1), 178-187 (DOI: 10.1002/prot.24722)
76. Bis-Fe(IV): Nature's sniper for long-range oxidation
Geng J, Davis I, Liu F, and Liu A*
J. Biol. Inorg. Chem., 2014, 19(7), 1057-1067 (Invited Review Article) (DOI: 10.1007/s00775-014-1123-8) 
75. Amidohydrolase Superfamily
Liu A* and Huo L
Encyclopedia of Life Sciences, 2014, 1-11 (DOI: 10.1002/9780470015902.a0020546.pub2) 
74. Heme-dependent dioxygenases in tryptophan oxidation
Geng J and Liu A*
Arch. Biochem. Biophys., 2014, 544, 18-26 (Invited Review Article) (DOI: 10.1016/j.abb.2013.11.009) 
73. The Power of two: Arginine 51 and arginine 239* from a neighboring subunit are essential for catalysis in α-amino-β-carboxymuconate-ε-semialdehyde
decarboxylase
Huo L, Davis I, Chen L, and Liu A*
J. Biol. Chem., 2013, 288(43), 30862-30871 (DOI: 10.1074/jbc.M113.496869)
72. Pirin is an iron-dependent redox regulator of NF-κB
Liu F, Rehmani I, Esaki S, Fu R, Chen L, Serroano V, and Liu A*
Proc. Natl. Acad. Sci. U.S.A., , 2013, 110(24), 9722-9727 (PNAS Direct Submission) (DOI: 10.1073/pnas.1221743110)
(** Faculty of 1000 recommended article )
71. Tryptophan-mediated charge-resonance stabilization in the bis-Fe(IV) redox state of MauG
Geng J, Dornevil K, Davidson VL, and Liu A*
Proc. Natl. Acad. Sci. U.S.A., , 2013, 110(24), 9639-9644 (PNAS Direct Submission) (DOI: 10.1073/pnas.1301544110) 
70. Diradical intermediate within the context of tryptophan tryptophylquinone biosynthesis
Yukl ET, Liu F, Krzystek J, Shin S, Jensen LMR, Davidson VL, Wilmot CM,* and Liu A*
Proc. Natl. Acad. Sci. U. S. A., 2013, 110(12), 4569-4573 (PNAS Direct Submission) (DOI: 10.1073/pnas.1215011110) 
* Faculty of 1000 recommended article
69. Development of a CZE-ESI-MS assay with a sulfonated capillary for profiling picolinic acid and quinolinic acid formation in multienzyme system
Wang X, Davis I, Liu A,* and Shamsi SA*
Electrophoresis, 2013, 34(12), 1828-1835 (DOI: 10.1002/elps.201200679) 
68. An unexpected copper catalyzed 'reduction' of an arylazide to amine through the formation of a nitrene intermediate
Peng H, Dornevil K, Draganov A, Chen W, Dai C, Nelson WH, Liu A,* and Wang B*
Tetrahedron, 2013, 69, 5079-5085 (dedicated to the memory of Professor William H. Nelson) (DOI: 10.1016/j.tet.2013.04.091) 
67. Improved separation and detection of picolinic acid and quinolinic acid by capillary electrophoresis-mass spectrometry: Application to the analysis of human cerebrospinal fluid
Wang X, Davis I, Liu A, Miller A, and Shamsi SA*
J. Chromatogr. A., 2013, 1316, 147-153 (DOI: doi.org/10.1002/elps.201200679)
66. Chemical rescue of the distal histidine mutants of tryptophan 2,3-dioxygenase
Geng J, Dornevil K, and Liu A*
J. Am. Chem. Soc.2012, 134, 12209-12218 (DOI: 10.1021/ja304164b)
65. Evidence for a dual role of an active site histidine in α -amino-β - carboxymuconate- ε - semialdehyde decarboxylase
Huo L, Fielding AJ, Chen Y, Li T, Iwaki H, Hosler JP, Chen L, Hasegawa Y, Que Jr, L, and Liu A*
Biochemistry, 2012, 51(29), 5811-5821 (DOI: doi.org/10.1021/bi300635b) 
64. Effects of the loss of the axial tyrosine ligand of the low-spin heme of MauG on its physical properties and reactivity
Tarboush NA, Shin S, Geng J, Liu A, and Davidson VL*
FEBS Lett., 2012, 586, 4339-4343 (DOI: 10.1016/j.febslet.2012.10.044)
63. Decarboxylation mechanisms in biological system
Li T, Huo L, Pulley C, and Liu A*
Bioorg. Chem., 2012, 43, 2-14 (DOI: 10.1016/j.bioorg.2012.03.001)
62. The role of calcium in metalloenzyme: Effects of calcium removal on the axial ligation geometry and magnetic properties of the catalytic diheme center in MauG
Chen Y, Naik SG, Krzystek J, Shin S, Nelson WH, Xue S, Yang JJ, Davidson VL, and Liu A*
Biochemistry, 2012, 51, 1586-1597 (DOI: 10.1021/bi201575f)
61. Tryptophan tryptophylquinone biosynthesis: A radical approach to posttranslational modification
Davidson VL and Liu A
Biochim. Biophys. Acta, 2012, 1824, 1299-1305 (DOI: 10.1016/j.bbapap.2012.01.008)
60. Proline 107 is a major determinant in maintaining the structure of the distal pocket and reactivity of the high-spin heme of MauG
Feng M, Jensen LMR, Yukl ET, Wei X, Liu A, Wilmot CM, and Davidson VL*
Biochemistry, 2012, 51(8), 1598-1606 (DOI: 10.1021/bi201882e)
59. The roles of Rhodobacter sphaeroides copper chaperones PCuAC and Sco (PrrC) in the assembly of the copper centers of the aa3-type and the cbb3-type cytochrome c oxidases
Thompson AK, Gray J, Liu A, Hosler JP*
Biochim. Biophys. Acta, 2012, 1817, 955-964 (DOI: 10.1016/j.bbabio.2012.01.003)
58. Synthesis, characterisation, and preliminary in vitro studies of vanadium(IV) complexes with a schiff base and thiosemicarbazones as mixed ligands
Lewis NA, Liu F, Seymour L, Magnusen A, Erves TR, Arca JF, Beckford FA, Venkatraman R, González-Sarrías A, Fronczek FR, VanDerveer DG, Seeram NP, Liu A, Jarrett WJ, Holder AH*
Eur. J. Inorg. Chem., 2012 , 4, 664-677 (DOI: 10.1002/ejic.201100898)
57. Mutagenesis of tryptophan199 suggests that electron hopping is required for MauG-dependent tryptophan tryptophylquinone biosynthesis
Tarboush NA, Jensen LMR, Yukl ET, Geng J, Liu A, Wilmot CM, and Davidson VL
Proc. Natl. Acad. Sci. U.S.A., 2011, 108(41), 16956-16961 (DOI: 10.1073/pnas.1109423108) 
56. The reactivation mechanism of tryptophan 2,3-dioxygenase by hydrogen peroxide
Fu R, Gupta R, Geng J, Dornevil K, Wang S, Hendrich MP, and Liu A*
J. Biol. Chem., 2011, 286(30), 26541-26554 (DOI: 10.1074/jbc.M111.253237)
55. Nature's strategy for oxidizing tryptophan: EPR and Mössbauer characterization of the unusual high-valent heme iron intermediates
in: Mössbauer Spectroscopy: Applications in Chemistry, Biology, Industry, and Nanotechnology.
Dornevil K and Liu A,* edited by Virender K. Sharma, Goestar Klingelhoefer, and Tetsuaki Nishida, 2013, pp. 315-323 ISBN 978-1-118-05724-7
54. Redox and oxygen sensing in the regulation of transcription by metalloproteins
in: Molecular Basis of Oxidative Stress: Chemistry, Mechanisms, and Disease Pathogenesis.
Rehmani I, Liu F and Liu A,* edited by Frederick A. Villamena, John Wiley & Sons, Inc., 2013, pp. 179-201 ISBN 978-0-470-57218-4
53. The tightly bound calcium of MauG is required for tryptophan tryptophylquinone cofactor biosynthesis
Shin S, Feng M, Chen Y, Jensen LMR, Tachikawa H, Wilmot CM, Liu A, and Davidson VL*
Biochemistry, 2011, 50, 144-150 (DOI: 10.1021/bi101819m)
52. Proline 96 of the copper ligand loop of amicyanin regulates electron transfer from methylamine dehydrogenase by positioning other residues at the protein-protein interface
Choi M, Sukumar N, Mathews FS, Liu A, and Davidson VL*
Biochemistry, 2011, 50(7), 1265-1273 (DOI: 10.1021/bi101794y)
51. EPR and Mössbauer spectroscopy show inequivalent hemes in tryptophan dioxygenase
Gupta R, Fu R, Liu A, and Hendrich MP*
J. Am. Chem. Soc., 2010, 132(3), 1098-1109 (DOI: 10.1021/ja908851e)
50. Mutagenic analysis of Cox11 of Rhodobacter sphaeroides: Insights into the assembly of CuB of cytochrome c oxidase
Thompson, AK, Smith D, Gray J, Carr HS, Liu A, Winge DR, Hosler JP*
Biochemistry, 2010, 49(27), 5651-5661 (DOI: 10.1021/bi1003876)
49. Heme iron nitrosyl complex of MauG reveals efficient redox equilibrium between hemes with only one heme exclusively binding exogenous ligands
Fu R, Liu F, Davidson VL, and Liu A*
Biochemistry, 2009, 48(49), 11603-11605 (DOI: 10.1021/bi9017544)
48. Electron Paramagnetic Resonance (EPR) in Enzymology
Liu A
Wiley Encyclopedia of Chemical Biology, 2008, 1, 591-601 (DOI: 10.1002/9780470048672.wecb668)
47. A single EF-hand isolated from STIM1 forms dimer in the absence and presence of Ca2+
Huang Y, Zhou Y, Wong HC, Chen Y, Wang S, Castiblanco A, Liu A, Yang JJ*
FEBS J. 2009, 276, 5589-5597 (DOI: 10.1111/j.1742-4658.2009.07240.x)
46. Defining the role of the axial ligand of the type 1 copper site in amicyanin by replacement of methionine with leucine
Choi M, Sukumar N, Liu A, and Davidson VL*
Biochemistry, 2009, 48(39), 9174-9184 (DOI: 10.1021/bi900836h)
45. A catalytic di-heme bis-Fe(IV) form of MauG, Alternative to an Fe(IV)=O porphyrin radical
Li X, Fu R, Lee S, Krebs C, Davidson VL,* and Liu A*
Proc. Natl. Acad. Sci. U.S.A., 2008, 105(25), 8597-8600 (PNAS Direct Submission) (DOI: 10.1073/pnas.0801643105)
44. Kinetic and physical evidence that the di-heme enzyme MauG tightly binds to a biosynthetic precursor of methylamine dehydrogenase with incompletely formed tryptophan tryptophylquinone
Li X, Fu R, Liu A*, and Davidson VL*
Biochemistry, 2008, 47(9), 2908–2912 (DOI: 10.1021/bi702259w)
43. Purification and characterization of the epoxidase catalyzing the formation of fosfomycin from Pseudomonas syringae
Munos JW, Moon S-J, Mansoorabadi SO, Hong L, Yan F, Liu A, and Liu H-w*
Biochemistry, 2008, 47(33), 8726–8735 (DOI: 10.1021/bi800877v)
42. Amidohydrolase Superfamily
Liu A*, Li T, and Fu R
Encyclopedia of Life Sciences, 2007, 1-8 (DOI: 10.1002/9780470015902.a0020546)
41. Determination of the substrate binding mode to the active site iron of (S)-2-hydroxypropyl phosphonic acid epoxidase using 17O-enriched substrates
Yan F, Moon S-J, Liu P, Zhao Z, Lipscomb JD, Liu A, and Liu H-w*
Biochemistry, 2007, 46(44), 12628-12638 (DOI: 10.1021/bi701370e)
40. Detection of transient intermediates in the metal-dependent non-oxidative decarboxylation catalyzed by α-amino-β-carboxymuconic-ε-semialdehyde decarboxylase
Li T, Ma J, Hosler JP, Davidson VL, and Liu A*
J. Am. Chem. Soc., 2007, 129(30), 9278-9279 (DOI: 10.1021/ja073648le)
39. Crystallographic analysis of α-amino-β-carboxymuconic-ε-semialdehyde decarboxylase: Insight into the active site and catalytic mechanism of a novel decarboxylation reaction
Martynowski D., Eyobo Y., Li T, Yang K., Liu A,* and Zhang H*
Biochemistry 2006, 45(21), 10412-10421 (DOI: 10.1021/bi060903q)
38. Transition metal-catalyzed nonoxidative decarboxylation reactions
Liu A* and Zhang H
Biochemistry, 2006, 45(35), 10407-10411 (a New Concepts in Biochemistry paper) (DOI: 10.1021/bi061031v)
37. α-Amino-b-carboxymuconic-ε-semialdehyde decarboxylase (ACMSD) is a new member of the amidohydrolase superfamily
Li T, Iwaki H, Fu R, Hasegawa Y, Zhang H, Liu A*
Biochemistry, 2006, 45(21), 6628-6634 (DOI: 10.1021/bi060108c)
36. The mechanism of inactivation of 3-hydroxyanthranilate-3,4-dioxygenase by 4-chloro-3 hydroxyanthranilate
Colabroy KL, Zhai H, Li T, Ge Y, Zhang Y, Liu A, Ealick SE, McLafferty FW, and Begley TP*
Biochemistry, 2005, 44(21), 7623–7631 (DOI: 10.1021/bi0473455)
35. Kinetic and spectroscopic characterization of ACMSD from Pseudomonas fluorescens reveals a pentacoordinate mononuclear metallocofactor
Li T, Walker AL, Iwaki H, Hasegawa Y, Liu A*
J. Am. Chem. Soc., 2005, 127(35), 12282–12290 (DOI: 10.1021/ja0532234)
