Welcome to the Department of Biochemistry and Biophysics
As one of the first departments of Biochemistry and Biophysics in the nation, we are proud of our strong tradition of combining cutting-edge technology with impactful biology. We continue to leverage this interdisciplinary approach to yield break-through discoveries in biomedicine.
Our faculty of over 30 primary and secondary members cover a broad range of research areas, with particular strengths in structural biology, chemical biology, gene regulation and protein folding.
We are also the proud home of the Eldridge Reeves Johnson Research Foundation which offers advanced physical instrumentation and instruction to researchers across campus.
We are actively growing, with several recent hires, and our faculty are broadly engaged across campus with many joint appointments in other departments, institutes and centers.
We welcome you to learn more about our department in the following pages or contact us.
Installation Phase One
News & Publications
- Garcia, Black, and Englander labs in Structure
The Garcia, Black and Englander labs combine forces to achieve a high-resolution view of histone tail dynamics during nucleosome assembly
- Sellmyer received NIH award
Mark Sellmyer received NIH Director's Early Independence Award for developing small molecule tools for molecular-imaging
- Black in Developmental Cell
Ben Black and colleagues determine how centromeres are maintained through DNA replication
- Kohli in Nature Biotechnology
Rahul Kohli & colleagues develop a new method for sequencing modified DNA
Seminars & Events
- Friday Research Discussion | Wand Lab
Some new ideas in drug discovery
Ronen Marmorstein, PhD
The Marmorstein laboratory studies the molecular mechanisms of protein post- and co-translational modification with a particular focus on protein acetylation and phosphorylation and chromatin regulation. The laboratory uses a broad range of molecular, biochemical and biophysical research tools centered on macromolecular structure determination. The laboratory is particularly interested in gene regulatory proteins and their upstream signaling kinases that are aberrantly regulated in cancer and other age-related disorders, and the use of high-throughput small molecule screening and structure-based design strategies towards the development of protein-specific small-molecule probes to be used to further interrogate protein function and for development into therapeutic agents.
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