Welcome to the Department of Biochemistry and Biophysics
As one of the first departments of Biochemistry and Biophysics in the nation, we are proud of our strong tradition of combining cutting-edge technology with impactful biology. We continue to leverage this interdisciplinary approach to yield break-through discoveries in biomedicine.
Our faculty of over 30 primary and secondary members cover a broad range of research areas, with particular strengths in structural biology, chemical biology, gene regulation and protein folding.
We are also the proud home of the Eldridge Reeves Johnson Research Foundation which offers advanced physical instrumentation and instruction to researchers across campus.
We are actively growing, with several recent hires, and our faculty are broadly engaged across campus with many joint appointments in other departments, institutes and centers.
We welcome you to learn more about our department in the following pages or contact us.
News & Publications
- Matschinsky receives Rolf Luft Award
Congratulations Franz M. Matschinsky, MD for receiving the 2020 Rolf Luft Award from the Karolinska Institute for outstanding scientific contribution in endocrinology and diabetes
- Marmorstein Lab in Nature Communications
Molecular basis for N-terminal acetylation by human NatE and its modulation by HYPK
- Moiseenkova-Bell Lab in Cell Calcium
Structural insights into the gating mechanisms of TRPV channels
- Vinogradov Lab Collaborates in Nature Communications
Tissue pO2 distributions in xenograft tumors dynamically imaged by Cherenkov-excited phosphorescence during fractionated radiation therapy
Seminars & Events
- Faculty Candidate Seminar | Serena Sanulli, PhD
Mon, February 24, 2020 • 1:00 pm | BRB 251
Heterochromatin organization and dynamics
- Raiziss Rounds Seminar | Adam Cohen, PhD
Thurs, February 27, 2020 • 12 noon | Austrian Auditorium, CRB
Bringing bioelectricity to light
- Friday Research Discussions | Chang Lab
Fri, February 28, 2020 • 3:30 pm | JF Library, 2nd Floor Anatomy-Chemistry Building
In situ structural study of molecular machines involved in microbial pathogenesis
Welcome to our newest faculty member, George Burslem. Dr. Burslem is an Assistant Professor in the Department of Biochemistry and Biophysics with a secondary appointment in Cancer Biology and affiliations to the Penn Epigenetics Institute and the Basser Center. George joined the department in January 2020 after a postdoctoral fellowship at Yale University with Prof. Craig Crews.
The Burslem Lab is interested in understanding and modulating lysine post-translational modifications, particularly ubiquitination and acetylation. To do this they employ a wide variety of techniques including synthetic organic chemistry, biochemistry, molecular biology and cell biology to gain new insights as well as develop new chemical biology tools and potential therapeutic approaches. George’s recruitment to Penn strengthens our presence in Chemical Biology and highlights the collaborative nature of research across the Penn campus.
© The Trustees of the University of Pennsylvania | Site best viewed in a supported browser. | Report Accessibility Issues and Get Help | Site Design: PMACS Web Team.