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Faculty by Research Interests
Control of gene expression and cellular programming
Dreyfuss, Garcia, Gardini, Gupta, Kohli, Lewis, Liu, Lynch, Marmorstein, Murakami, Shorter, VanDuyne, Wand, Wilusz
Cell signaling and intracellular trafficking
Black, Discher, Dreyfuss, Garcia, Kohli, Lynch, Wand
Chemical and structural biology
Axelsen, Black, Englander, Gupta, Lewis, Marmorstein, Moiseenkova-Bell, Murakami, Penning, Petersson, Sellmyer, Sharp, Shorter, Skordalakes, Speicher, Tommos, VanDuyne, Vinogradov, Wand, Wilusz
Bioenergetics, metabolism, and membranes
Axelsen, Daldal, Discher, Doliba, Englander, Goldman, Matschinsky, Moiseenkova-Bell, Penning, Sharp, Vinogradov, Wilson
Training opportunities are available in the following laboratories:
Paul H. Axelsen, MD | Protein misfolding diseases and pathological protein-lipid interactions; rational drug design
Ben E. Black, PhD | Chromosome segregation; chromatin structure; epigenetic centromere specification; hydrogen/deuterium exchange
Fevzi Daldal, PhD | Genetics, structure-function, regulation and biogenesis of cytochromes
Bohdana Discher PhD | Designing and interfacing proteins with membranes and electronic devices
Nicolai Doliba, PhD | Bioenergetics, metabolism, and membranes
Gideon Dreyfuss, PhD | Nuclear transport, hnRNP complexes, RNA-binding proteins, spinal muscular Atrophy
P. Leslie Dutton, PhD | Oxidoreductase engineering; design and chemical synthesis of redox proteins
S. Walter Englander, PhD | Protein folding; structure, structure change, and dynamics; H-exchange; NMR
Benjamin A. Garcia, PhD | Quantitative proteomics for understanding signaling pathways
Alessandro Gardini, PhD | Understanding the role of enhancers and noncoding RNAs in transcriptional regulation in mammals
Jerry Glickson, PhD | Molecular imaging: NMR spectroscopy and imaging of cancer; optical imaging of cancer; nanotechnology
Yale E. Goldman, MD, PhD | Molecular motors and protein synthesis studied by single molecule Biophysics
Kushol Gupta, PhD | Structural biology of large macromolecular assemblies that regulate genetic information; X-ray crystallography; small-angle X-ray and neutron scattering
Rahul Kohli, MD, PhD | Investigating the enzymatic basis for diversity generation in the immune system and pathogens; enzyme mechanisms, chemical biology, protein evolution
Mitchell Lewis, DPhil | Gene regulation; protein crystallography; structural basis of recognition
Kristen W. Lynch, PhD | Mechanism and consequences of regulated alternative splicing
Ronen Marmorstein, PhD | X-ray crystallography, chromatin regulation, tumor suppressors, oncoproteins, kinases, aging, structure-based inhibitor design
Kenji Murakami, PhD | Transcription initiation and regulation in eukaryote Itzhak Nissim
Trevor M. Penning, PhD | Structure-function of aldo-keto reductases; role in steroid hormone action and chemical carcinogenesis
Mark. A. Sellmyer, MD, PhD | Molecular tools for cancer, infection, and immunology
Kim A. Sharp, PhD | Graduate Group Chair, Theory of protein and nucleic acid structure and function
James Shorter, PhD | Regulation of beneficial or neuropathogenic prions and amyloids by protein-remodeling factors, molecular chaperones, and small molecules
Emmanuel Skordalakes, PhD | X-ray crystallography; telomere biology; cancer and aging
David W. Speicher, PhD | Cancer proteomics; structure-function of membrane associated proteins: protein chemistry and mass spectrometry
Cecilia Tommos, PhD | Protein radicals and electrochemistry; cation-x interactions; protein forced folding
Gregory D. Van Duyne, PhD | Structural biology; protein-protein interactions; x-ray crystallography
Sergei A. Vinogradov, PhD | Functional macromolecules, optical imaging probes, porphyrin chemistry, dendrimer chemistry, oxygen microscopy and tomography
A. Joshua Wand, PhD | Protein structure and dynamics; molecular recognition and signal transduction; NMR spectroscopy
Jeremy E. Wilusz, PhD | Regulation of noncoding RNA biogenesis and function