Borrowing a Page from Cancer’s Playbook, Scientists Learn to Evade their Own Therapies

An essay on how scientists are tackling various challenges associated with improving CAR T cell therapy includes the example of an “epitope editing” approach developed by Saar Gill, MD, PhD, an associate professor of Hematology-Oncology, which targets CD45—a surface marker found on nearly all blood cells, including nearly all blood cancer cells.