Bryson W. Katona, MD/PhD
Jeffery and Cynthia King Assistant Professor of Lynch Syndrome Research

- Director, Gastrointestinal Cancer Genetics Program, Penn Medicine
- Director, Gastrointestinal Cancer Risk Evaluation Program, Penn Medicine
- Member, Abramson Cancer Center - Cancer Control Program
- Director, Lynch Syndrome Program, Penn Medicine
- Member, Institute for Translational Medicine and Therapeutics - University of Pennsylvania
- Member, Center for Molecular Studies in Digestive and Liver Diseases - University of Pennsylvania
Department: Medicine
Division: Gastroenterology
Contact Information
Perelman Center for Advanced Medicine
3400 Civic Center Boulevard
751 South Pavilion
Philadelphia, PA 19104
Office: 215-349-8222
Fax: 215-349-5915
Email: bryson.katona@pennmedicine.upenn.edu
I3H Keywords
- Cancer Immunology and Immunotherapy
Publications
Links
Education
-
BA (Chemistry)
University of Pennsylvania, 2002 -
MS (Chemistry)
University of Pennsylvania, 2002 -
MD
Washington University in St. Louis School of Medicine, 2009 -
PhD (Biochemistry)
Washington University in St. Louis School of Medicine, 2009
Post-Graduate Training
-
Resident in Internal Medicine
University of Pennsylvania, 2009 - 2011 -
Fellow in Gastroenterology
University of Pennsylvania, 2011 - 2015
Certifications
- Board certified in Internal Medicine, 2012
- Board certified in Gastroenterology, 2014
Description of Clinical Expertise
Hereditary gastrointestinal cancer and polyposis syndromes. Gastrointestinal cancer risk evaluation.
Description of Research Expertise
Hereditary gastrointestinal cancer and polyposis syndromes, especially hereditary colorectal cancer and hereditary gastric cancer.
Selected Publications
- Katona BW, Lubinski J, Pal T, Huzarski T, Foulkes WD, Moller P, Eisen A, Randall Armel S, Neuhausen SL, Raj R, Aeilts A, Singer CF, Bordeleau L, Karlan B, Olopade O, Tung N, Zakalik D, Kotsopoulos J, Fruscio R, Eng C, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. : The incidence of pancreatic cancer in women with a BRCA1 or BRCA2 mutation Cancer 131 : e35666, Jan 2025
- Mirda D, Dungan M, Ren Y, Li H, Katona BW. : Colorectal Neoplasia Detection Rates in Lynch Syndrome Cancers (Basel) 16 : 4021, Nov 2024
- Phung L, Wood E, Egleston B, Hoffman-Andrews L, Ofidis D, Howe S, Mim R, Griffin H, Fetzer D, Owens A, Domchek S, Pyeritz R, Katona B, Kallish S, Sirugo G, Weaver J, Nathanson KL, Rader DJ, Bradbury AR. : Facilitating return of actionable genetic research results from a biobank repository: Participant uptake and utilization of digital interventions HGG Adv 5 : 100346, Oct 2024
- Cheng HH, Shevach JW, Castro E, Couch FJ, Domchek SM, Eeles RA, Giri VN, Hall MJ, King MC, Lin DW, Loeb S, Morgan TM, Offit K, Pritchard CC, Schaeffer EM, Szymaniak BM, Vassy JL, Katona BW, Maxwell KN. : BRCA1, BRCA2, and Associated Cancer Risks and Management for Male Patients: A Review JAMA Oncol 10 : 1272-1281, Sep 2024
- Majer AD, Hua X, Katona BW. : Menin in Cancer Genes (Basel) 15(9) : 1231, Sep 2024
- Ness RM, Llor X, Abbass MA, Bishu S, Chen CT, Cooper G, Early DS, Friedman M, Fudman D, Giardiello FM, Glaser K, Gurudu S, Hall M, Huang LC, Issaka R, Katona B, Kidambi T, Lazenby AJ, Maratt J, Markowitz AJ, Marsano J, May FP, Mayer RJ, Olortegui K, Patel S, Peter S, Porter LD, Shafi M, Stanich PP, Terdiman J, Vu P, Weiss JM, Wood E, Cassara CJ, Sambandam V. : NCCN Guidelines® Insights: Colorectal Cancer Screening, Version 1.2024 J Natl Compr Canc Netw 22(7) : 438-446, Sep 2024
- Blackford AL, Canto MI, Dbouk M, Hruban RH, Katona BW, Chak A, Brand RE, Syngal S, Farrell J, Kastrinos F, Stoffel EM, Rustgi A, Klein AP, Kamel I, Fishman EK, He J, Burkhart R, Shin EJ, Lennon AM, Goggins M. : Pancreatic Cancer Surveillance and Survival of High-Risk Individuals JAMA Oncol 10 : 1087-1096, Aug 2024
- Niccum BA, Coughlin S, Clay D, Heiman J, Buckley KH, Dungan M, Daniel MG, Ruiz J, Maxwell KN, Domchek SM, Leung G, Ahmad NA, Ginsberg GG, Kochman ML, Katona BW. : Prevalence of H. pylori and Gastric Intestinal Metaplasia in BRCA1 and BRCA2 Carriers Cancer Prev Res (Phila) 17 : 305-309, Jul 2024
- Cappadocia J, Aiello LB, Kelley MJ, Katona BW, Maxwell KN; Penn Medicine BioBank, Regeneron Genetics Center. : PMS2CL interference leading to erroneous identification of a pathogenic PMS2 variant in Black patients Genet Med Open 2 : 101858, Jun 2024
- Wang L, Levinson R, Mezzacappa C, Katona BW. : Review of the cost-effectiveness of surveillance for hereditary pancreatic cancer Fam Cancer 23(3) : 351–360, May 2024