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Welcome to the Katona Lab

Our lab and research program is an exciting, highly collaborative, and interdisciplinary program focused on gastrointestinal cancer and hereditary gastrointestinal cancer predisposition syndromes.  Ongoing research activities in this area span the spectrum of basic science, translation studies, and clinical studies, and involve active collaborations across the Perelman School of Medicine, Abramson Cancer Center, and the University of Pennsylvania.  Active research projects in our group, as detailed on the Research page, include understanding the biology of colorectal tumorigenesis through the use of mouse models and human-derived organoids, studying the role of the immune system in Lynch syndrome pathogenesis, implementation of early detection of pancreatic cancer in individuals at high-risk, investigating the role of the microbiome in colonic polyposis, and characterizing genetic susceptibility for gastric cancer.

Recent News

September 2021

Welcome to Keely Beyries, who joined our group as a Research Specialist A, as well as Thomas Nyul who joined as a Student Researcher.  Congratulations also to Taylor Hojnacki for her promotion to Research Specialist B.

August 2021

This month, published in Cancer Prevention Research, we report our outcomes of pancreatic cancer surveillance in BRCA1, BRCA2, PALB2, and ATM carriers, and illustrate that surveillance can be considered in these individuals at increased pancreatic cancer risk.

June 2021

Welcome to Daniel Clay, who joined our group as a Clinical Research Assistant.  Jessey Yang, who is a current University of Pennsylvania undergraduate student, also joined our group.

April 2021

Now published in Pancreatology, the COVID-19 pandemic led to significant disruptions in pancreatic cancer surveillance amongst high-risk individuals in the multi-center CAPS5 Study.

Pancreatology 2021 article header

February 2021

Welcome to Jordan Heiman, who joined our group as a Clinical Research Coordinator.

Just published in Cancer Prevention Research, COVID-19 led to significant disruptions in Lynch syndrome surveillance, especially amongst young individuals.

COVID-19 disruptions to Lynch syndrome paper header

See the News section for other exciting announcements.