Publications

Full list of publications Katona Lab Publications

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  • Kole H. Buckley, Yuhan Zhu, Kevin Dinh, Ryan Hausler, Rohan Gala, Sophia R. Spiegel, Rosella Delgado, Daniel G. Clay, Gregory M. Kelly, Jamie Brower, Susan M. Domchek, Kara N. Maxwell, Bryson W. Katona. Prevalence of Helicobacter pylori Exposure and Risk Factors Among BRCA1 and BRCA2 Carriers.  IJC (2026): 1–6. International Journal of Cancer Article

  • Mirda D, Hao J, Dungan M, Youngman J, Ren Y, Li H, Long JM, Katona BW. Factors Associated with Adherence to Recommended Colorectal Surveillance Intervals in Lynch Syndrome. Cancers (Basel). 2026 Jun 22;18(12):2010. Cancers Article

  • Yang H, Dungan M, Madhu B, Beyries K, Wang X, Kilpatrick R, Chen B, Oh S, Berkowitz M, Smith D, Zhou C, Koralov SB, Axelrad J, Lengner CJ, Belle N, Bewtra M, Katona BW, Cadwell K. MAIT cell enrichment in Lynch syndrome is associated with immune surveillance and colorectal cancer risk. Gut. 2026 May 19:gutjnl-2025-337343. Gut Article

  • Kole H. Buckley, Michaela E. Dungan, Kevin Dinh, Gregory M. Kelly, Ryan Hausler, Kate E. Bennett, Daniel G. Clay, Julia E. Youngman, Ariana D. Majer, Keely A. Beyries, Blake A. Niccum, Sydney M. Shaffer, Tatiana A. Karakasheva, Kathryn E. Hamilton, Michael L. Kochman, Gregory G. Ginsberg, Nuzhat Ahmad, Kara N. Maxwell, Bryson W. Katona; Gastric Epithelium from BRCA1 and BRCA2 Carriers Harbors Increased Double-Stranded DNA Damage and Enhanced Growth Potential. Mol Cancer Res 1 July 2026; 24 (7): 589–600. Molecular Cancer Research Article

  • Vadaketh J, Konigsberg J, Elghawy O, Dinh K, Zhu L, Youngman J, Dungan M, Pulaski M, Long JM, Buckley KH, Katona BW. Yield of repeat gastric biopsies and Helicobacter pylori serological assessment in Lynch syndrome. Cancer Treat Res Commun. 2026;46:101081. Cancer Treatment and Research Communications Article

  • Shen MJ, Jamali A, Katona BW. Challenges of early detection of pancreatic cancer. J Clin Invest. 2025 Oct 15;135(20):e191942. Journal of Clinical Investigation Article

  • Manam A, Everett JN, Haraldsdottir S, Hart PA, Kaul V, Klute K, Schrader KA, Sussman DA, Katona BW; PRECEDE Consortium. Areas of Uncertainty in Pancreatic Cancer Surveillance: A Survey Across the International Pancreatic Cancer Early Detection (PRECEDE) Consortium. JCO Precis Oncol. 2025 Oct;9:e2500696. JCO Precision Oncology Article

  • Snyder GG, Clay D, Karley S, Pipito S, Mueller R, Bradbury A, Maxwell K, Nathanson KL, Rohanizadegan M, Shah P, Domchek SM, Long JM, Katona BW. Assessment of barriers to pancreatic cancer surveillance in high-risk individuals. J Genet Couns. 2025 Oct;34(5):e70117. Journal of Genetic Counseling Article

  • Katona BW, Shukla A, Hu W, Nyul T, Dudzik C, Arvanitis A, Clay D, Dungan M, Weber M, Tu V, Hao F, Gan S, Chau L, Buchner AM, Falk GW, Jaffe DL, Ginsberg G, Palmer SN, Zhan X, Patterson AD, Bittinger K, Ni J. Microbiota and metabolite-based prediction tool for colonic polyposis with and without a known genetic driver. Gut Microbes. 2025 Dec;17(1):2474141. Gut Microbes Article

  • Latham A, Liu YL, Constantino G, Borio M, McCoy S, Dudzik C, Heiman J, Kemel Y, Ukaegbu C, Carlo MI, Ranganathan M, Kane S, Long JM, Syngal S, Markowitz AJ, Stadler ZK, Yurgelun MB, Katona BW. Neoplasia Detection Through Colonic Surveillance Among Young Individuals With MSH6 / PMS2 -Associated Lynch Syndrome. Am J Gastroenterol. 2025 Nov 1;120(11):2670-2678. American Journal of Gastroenterology Article

  • Fernandes CJ, Du YK, Naumer A, Kagami LA, Le A, Good M, Duvall M, Powers J, Zelley K, Maese LD, MacFarland S, Kohlmann W, Maxwell KN, Katona BW. Pancreatic Cancer Risk and Screening Outcomes in Li-Fraumeni Syndrome. Pancreas. 2025 Aug 1;54(7):e618-e623. Pancreas Article

  • Katona BW, Lubinski J, Pal T, Huzarski T, Foulkes WD, Moller P, Eisen A, Randall Armel S, Neuhausen SL, Raj R, Aeilts A, Singer CF, Bordeleau L, Karlan B, Olopade O, Tung N, Zakalik D, Kotsopoulos J, Fruscio R, Eng C, Sun P, Narod SA; Hereditary Breast Cancer Clinical Study Group. The incidence of pancreatic cancer in women with a BRCA1 or BRCA2 mutation. Cancer. 2025 Jan 1;131(1):e35666. Cancer Article

  • Lau-Min KS, Rochester S, Grabill M, Long JM, McKenna DB, Powers J, Bracy D, Boisseau L, Gabriel P, Oyer R, Domchek SM, Rendle KA, Nathanson KL, Katona BW. Pilot implementation study of a default genetic referral process for patients with early-onset colorectal cancer. Genet Med Open. 2024 Nov 19;3:101902. Genetics in Medicine Open Article

  • Mirda D, Dungan M, Ren Y, Li H, Katona BW. Colorectal Neoplasia Detection Rates in Lynch Syndrome. Cancers (Basel). 2024 Nov 30;16(23):4021. Cancers Article

  • Wang L, Levinson R, Mezzacappa C, Katona BW. Review of the cost-effectiveness of surveillance for hereditary pancreatic cancer. Fam Cancer. 2024 Aug;23(3):351-360. Familial Cancer Article

  • Majer, A. D., Hua, X., & Katona, B. W. Menin in Cancer. Genes. 2024 15(9), 1231. Genes Article

  • Blake A. Niccum, Sarah Coughlin, Daniel Clay, Jordan Heiman, Kole H. Buckley, Michaela Dungan, Michael G. Daniel, Jose Ruiz, Kara N. Maxwell, Susan M. Domchek, Galen Leung, Nuzhat A. Ahmad, Gregory G. Ginsberg, Michael L. Kochman, Bryson W. Katona; Prevalence of H. pylori and Gastric Intestinal Metaplasia in BRCA1 and BRCA2 Carriers. Cancer Prev Res (Phila). 1 July 2024; 17 (7): 305–309. Cancer Prevention Research Article

  • Buckley KH , Beyries KA , Ryeom S , Yoon SS , Katona BW. Establishment and Characterization of Patient-derived Gastric Organoids from Biopsies of Benign Gastric Body and Antral Epithelium. J. Vis. Exp. 2024 (203), e66094. JoVE Article

  • Pulaski M, Dungan M, Weber M, Constantino G, Katona BW. Low prevalence of gastric intestinal metaplasia and Helicobacter pylori on surveillance upper endoscopy in Lynch syndrome. Fam Cancer. 2024 Mar;23(1):23-27. Familial Cancer Article

  • Anez-Bruzual I, Coughlin S, Clay D, Heiman J, Dungan M, Weber M, Almario CV, Leung G, Ahmad NA, Ginsberg GG, Kochman ML, Valverde KD, Long JM, Katona BW. Assessment of the Psychosocial Impact of Pancreatic Cancer Surveillance in High-Risk Individuals. Cancers (Basel). 2023 Dec 23;16(1):86. Cancers Article

  • Katona BW, Worthington C, Clay D, Cincotta H, Ahmad NA, Ginsberg GG, Kochman ML, Brand RE. Outcomes of the IMMray PanCan-d Test in High-Risk Individuals Undergoing Pancreatic Surveillance: Pragmatic Data and Lessons Learned.  JCO Precis Oncol. 2023 Sep;7:e2300445. JCO Precision Oncology Article

  • Lau-Min KS, Bleznuck J, Wollack C, McKenna DB, Long JM, Hubert AP, Johnson M, Rochester SE, Constantino G, Dudzik C, Doucette A, Wangensteen K, Domchek SM, Landgraf J, Chen J, Nathanson KL, Katona BW. JCO Clin Cancer Inform. 2023 Aug;7:e2300024. JCO Clinical Cancer Informatics Article

  • Fillman C, Anantharajah A, Marmelstein B, Dillon M, Horton C, Peterson C, Lopez J, Tondon R, Brannan T, Katona BW. Combining clinical and molecular characterization of CDH1: a multidisciplinary approach to reclassification of a splicing variant. Fam Cancer. 2023 Oct;22(4):521-526. Familial Cancer Article

  • Katona BW, Klute K, Brand RE, Everett JN, Farrell JJ, Hawthorne K, Kaul V, Kupfer SS, Paiella S, Simeone DM, Sussman DA, Zogopoulos G, Lucas AL, Kastrinos F; PRECEDE Consortium. Racial, Ethnic, and Sex-based Disparities among High-risk Individuals Undergoing Pancreatic Cancer Surveillance. Cancer Prev Res (Phila). 2023 Jun 1;16(6):343-352. Cancer Prevention Research Article

  • Williams S, Ebrahimzadeh JE, Clay D, Constantino G, Heiman J, Wangensteen KJ, Valverde K, Mahmud N, Katona BW. Comparing telemedicine and in-person gastrointestinal cancer genetic appointment outcomes during the COVID-19 pandemic. Hered Cancer Clin Pract. 2023 May 8;21(1):6. Hereditary Cancer in Clinical Practice Article

  • Buckley K.H., Niccum B.A., Maxwell K.N., Katona B.W.  Gastric Cancer Risk and Pathogenesis in BRCA1 and BRCA2 Carriers, Cancers, 2022, 14(23), 5953. Cancers Article
  • Coughlin S.E., Heald B., Clark D.F., Nielsen S.M., Hatchell K.E., Esplin E.D., Katona B.W.  Multigene panel testing yields high rates of clinically actionable variants amongst colorectal cancer patients, JCO Precision Oncology, 2022. JCO PO Article
  • Long J.M., Ebrahimzadeh J., Stanich P.P., Katona B.W.  Endoscopic surveillance in patients with the highest risk of gastric cancer: Challenges and solutions.  Cancer Management and Research, 2022, 14, 2953-2969. Cancer Management and Research Article
  • Fernandes C.J., Leung G., Eads J., Katona B.W.  Current approaches to the diagnosis and management of gastroenteropancreatic neuroendocrine tumors, Gastroenterology Clinics of North America, 2022, 51(3), 625-647. GI Clinics of NA Article
  • Dbouk M., Katona B.W., Brand R.E., Chak A., Syngal S., Farrell J.J., Kastrinos F., Stoffel E.M., Blackford A.L., Rustgi A.K., Dudley B., Lee L.S., Chhoda A., Kwon R., Ginsberg G.G., Klein A.P., Kamel I., Hruban R.H., He J., Shin E.J., Lennon A.M., Canto M.I., Goggins M.  The Multicenter Cancer of Pancreas Screening (CAPS) Study: Impact on Stage and Survival, Journal of Clinical Oncology, 2022, 40(28), 3257-3266. JCO Article
  • Feng Z., He X., Zhang X., Wu Y., Xing B., Knowles A., Shan Q., Miller S., Hojnacki T., Ma J., Katona B.W., Gade T.P., Schrader J., Metz D.C., June C.H., Hua X.  Potent Suppression of Neuroendocrine Tumors and Gastrointestinal Cancers by CDH17CAR T Cells Without Toxicity to Normal Tissues, Nature Cancer, 2022, 3, 581-594.  Nature Cancer Article
  • Dmitrieva-Posocco O., Wong A.C., Lundgren P., Golos A.M., Descamps H.C., Dohnalová L., Cramer Z., Tian Y., Yueh B., Eskiocak O., Egervari G., Lan Y., Liu J., Fan J., Kim J., Madhu B., Schneider K.M., Khoziainova S., Andreeva N., Wang Q., Li N., Furth E.E., Bailis W., Kelsen J.R., Hamilton K.E., Kaestner K.H., Berger S.L., Epstein J.A., Jain R., Li M., Beyaz S., Lengner C.J., Katona B.W., Grivennikov S.I., Thaiss C.A., Levy M.  Beta-hydroxybutyrate suppresses colorectal cancer, Nature, 2022, 605(7908), 160-165.   Nature Article
  • Kumar S., Farha N., Burke C.A., Katona B.W.  Upper gastrointestinal cancer surveillance in Lynch syndrome, Cancers, 2022, 14:4. Cancers Article
  • Long J.M., Powers J.M., Katona B.W.  Evaluation of classic, attenuated, and oligopolyposis of the colon.  Gastroenterology Clinics of North America, 2022, 32(1), 95-112.  GI Endoscopy Clinics of North America Article  
  • DeJesse J., Vajravelu R.K., Dudzik C., Constantino G., Long J.M., Wangensteen K.J., Valverde K.D., Katona B.W.  Uptake and outcomes of small intestinal and urinary tract cancer surveillance in Lynch syndrome.  World Journal of Clinical Oncology, 2021, 12(11), 1023-1036. World Journal of Clinical Oncology Article  

  • Katona B.W., Long J.M., Ahmad N.A., Attalla S., Bradbury A.R., Carpenter E.L., Clark D.F., Constantino G., Das K.K., Domchek S.M., Dudzik C., Ebrahimzadeh J., Ginsberg G.G., Heiman J., Kochman M.L., Maxwell K.N., McKenna D.B., Powers J., Shah P.D., Wangensteen K., Rustgi A.K.  EUS-based pancreatic cancer surveillance in BRCA1/BRCA2/PALB2/ATM carriers without a family history of pancreatic cancer, Cancer Prevention Research, 2021, 14(11), 1033-1040.  Cancer Prevention Research Article  

  • Katona B.W., Mahmud N., Dbouk M., Ahmad N., Chhoda A., Dudley B., Hayat U., Kwon R.S., Lee L.S., Rustgi A.K., Ukaegbu C., Vasquez L., Volk S., Brand R.E., Canto M.I., Chak A., Farrell J.J., Kastrinos F., Stoffel E.M., Syngal S., Goggins M.  COVID-19 related pancreatic cancer surveillance disruptions amongst high-risk individuals, Pancreatology, 2021, 21(6), 1048-1051. 
    Pancreatology Article
  • McKenna D.B., Dudzik C., Kumar S., Mahmud N., Katona B.W.  COVID-19 disruptions to endoscopic surveillance in Lynch syndrome, Cancer Prevention Research, 2021, 14(5), 521-526.  
    Cancer Prevention Research Article
  • Kipnis S.T., Hung M., Kumar S., Heckert J.M., Lee H., Bennet B., Soulen M.C., Pryma D.A., Mankoff D.A., Metz D.C., Eads J.R., Katona B.W.  Laboratory, Clinical, and Survival Outcomes Associated With Peptide Receptor Radionuclide Therapy in Patients With Gastroenteropancreatic Neuroendocrine Tumors, JAMA Network Open, 2021, 4(3), e212274.  
    JAMA Network Open Article
  • Long J.M., Powers J.M., Stanich P.P., Katona B.W.   Clinical management of oligopolyposis of unknown etiology.  Current Treatment Options in Gastroenterology, 2021.  
    Current Treatment Options in Gastroenterology Article
  • MacFarland S.P., Ebrahimzadeh J.E., Zelley K., Begum L., Bass L.M., Brand R.E., Dudley B., Fishman D.S., Ganzak A., Karloski E., Latham A., Llor X., Plon S., Riordan M., Scollon S., Stadler Z.K., Syngal S., Ukaegbu C., Weiss J., Yurgelun M.B., Brodeur G.M., Mamula P., Katona B.W.  Phenotypic differences in Juvenile Polyposis Syndrome with or without a disease-causing SMAD4/BMPR1A variant, Cancer Prevention Research, 2021, 14, 215-222.  
    Cancer Prevention Research Article
  • Katona B.W., Hojnacki T., Glynn R.A., Paulosky K.E., Szigety K.M., Cao Y., Zhang X., Feng Z., He X., Ma J., Hua X.  Menin-mediated repression of glycolysis in combination with autophagy protects colon cancer against small molecule EGFR inhibitors, Molecular Cancer Therapeutics, 2020, 19, 2319-2329.  
    Molecular Cancer Therapeutics Article
  • Katona B.W., Powers J., McKenna D.B., Long J.M., Le A.N., Hausler R., Zelley K., Jennings S., Domchek S.M., Nathanson K.L., MacFarland S.P., Maxwell K.N.  Upper gastrointestinal cancer risk and surveillance outcomes in Li-Fraumeni syndrome, American Journal of Gastroenterology, 2020, 115(12), 2095-2097.  
    American Journal of Gastroenterology Article
  • Kumar S., Dudzik C.M., Reed M., Long J.M., Wangensteen K.J., Katona B.W.  Upper endoscopic surveillance in Lynch syndrome detects gastric and duodenal adenocarcinomas, Cancer Prevention Research, 2020, 13(12), 1047-1054.  
    Cancer Prevention Research Article
  • Ebrahimzadeh J.E., Long J.M., Wang L., Nathanson J.T., Siddique S.M., Rustgi A.K., Goldberg D.S., Katona B.W.  Associations of sociodemographic and clinical factors with gastrointestinal cancer risk assessment appointment completion.  Journal of Genetic Counseling, 2020, 29(4), 616-624.  
    Journal of Genetic Counseling Article
  • Heckert J.M., Kipnis S.T., Kumar S., Botterbusch S., Alderson A., Bennet B., Creamer C., Eads J.R., Soulen M.C., Pryma D.A., Mankoff D.A., Metz D.C., Katona B.W.  Abnormal pre-treatment liver function tests are associated with discontinuation of PRRT in a U.S.-based neuroendocrine tumor cohort.  The Oncologist, 2020, 25(7), 572-578.  
    The Oncologist Article
  • Clark D.F., Michalski S.T., Tondon R., Nehoray B., Ebrahimzadeh J., Hughes S.K., Soper E.R., Domchek S.M., Rustgi A.K., Pineda-Alvarez D., Anderson M.J., Katona B.W.  Loss-of-function variants in CTNNA1 detected on multigene panel testing in individuals with gastric or breast cancer.  Genetics in Medicine, 2020, 22(5), 840-846.  
    Genetics in Medicine Article
  • Katona B.W., Clark D.F., Domchek S.M.  CDH1 on multigene panel testing: Look before you leap. Journal of the National Cancer Institute, 2020, 112(4), 330-334.  
    Journal of the National Cancer Institute Article
  • Katona B.W. and Weiss J.M.  Chemoprevention of colorectal cancer.  Gastroenterology, 2020, 158(2), 368-388.  
    Gastroenterology Article
  • Kumar S., Long J.M., Ginsberg G.G., Katona B.W.  The role of endoscopy in the management of hereditary diffuse gastric cancer syndrome, World Journal of Gastroenterology, 2019, 25(23), 2878-2886.  
    World Journal of Gastroenterology Article
  • Katona B.W., Glynn R.A., Paulosky K.E., Feng Z., Davis C.I., Ma J., Berry C.T., Szigety K.M., Matkar S., Liu Y., Wang H., Wu Y., He X., Freedman B.D., Brady D.C., Hua X.  Combined menin and EGFR inhibitors synergize to suppress colorectal cancer via EGFR-independent and calcium-mediated repression of SKP2 transcription, Cancer Research, 2019, 79(9), 2195-2207.  
    Cancer Research Article
  • MacFarland S.P., Zelley K., Long J.M., McKenna D., Mamula P., Domchek S.M., Nathanson K.L., Brodeur G.M., Rustgi A.K., Katona B.W., Maxwell K.N.  Earlier colorectal cancer screening may be necessary in patients with Li-Fraumeni Syndrome, Gastroenterology, 2019, 156(1), 273-274.  
    Gastroenterology Article
  • McKenna D.B., Akker J.V.D., Zhou A.Y., Ryan L., Leon A., O'Connor R., Shah P.D., Rustgi A.K., Katona B.W.  Identification of a novel GREM1 duplication in a patient with multiple colon polyps, Familial Cancer, 2019, 18(1), 63-66.  
    Familial Cancer Article
  • Katona, B.W., Yurgelun, M.B., Garber, J.E., Offit, K., Domchek, S.M., Robson, M.E., Stadler, Z.K.  A counseling framework for moderate-penetrance colorectal cancer susceptibility genes, Genetics in Medicine, 2018, 20(11), 1324-1327.  
    Genetics in Medicine Article
  • Katona B.W. and Rustgi A.K.  Gastric Cancer Genomics: Advances and Future Directions.  Cell Mol. Gastroenterol. Hepatol., 2017, 3(2), 211-217.  
    Gastric Cancer Genomics Article
  • Katona B.W., Liu Y., Ma A., Jin J., Hua X.  EZH2 inhibition enhances the efficacy of an EGFR inhibitor in suppressing colon cancer cells.  Cancer Biol. Ther., 2014, 15(12), 1677-1687.  
    Cancer Biology & Therapy Article