Sarah Henrickson, MD/PhD
Assistant Professor of Pediatrics (Allergy/Immunology)

Department: Pediatrics
Division: Allergy/Immunology
Graduate Group Affiliations
Contact Information
Children's Hospital of Philadelphia
Allergy Immunology Division
3615 Civic Center Blvd
Philadelphia, PA 19104
Email: henricksons@email.chop.edu
I3H Keywords
- Allergy, Asthma, and Other Inflammatory Diseases
- Precision Immunology and Measuring Immune Health
- Systems Immunology and Genomics
Publications
Links
Education
-
BA
Harvard University, 2001 -
Ph.D.
Harvard Medical School, 2008 -
M.D.
Harvard Medical School, 2011
Post-Graduate Training
-
Intern in Pediatrics
Boston Children's Hospital Combined residency program in pediatrics, 2011 - 2012 -
Resident in Pediatrics
Boston Children's Hospital Combined residency, 2012 - 2013 -
Resident in Pediatrics
Children's Hospital of Philadelphia, 2013 - 2014 -
Fellow in Allergy and Immunology
Children's Hospital of Philadelphia, 2014 - 2017
Certifications
- Pediatrics, 2015
- Allergy and Immunology- certificate# 11418, 2016
Description of Clinical Expertise
Immune Deficiency
Asthma
Description of Research Expertise
Human Immunology
Immune Dysregulation
Mouse models of disease
Primary Immune Deficiency
Asthma
Obesity
Description of ITMAT Expertise
Human Immunology
Primary Immunodeficiency
Viral Infection
Vaccines
Selected Publications
- Henrickson SE*, Manne S*, Dolfi DV, Mansfield KD, Parkhouse K, MIstry RD, Alpern ER, Hensley SE, Sullivan KE, Coffin SE and EJ Wherry (* = co-first authors) : Genomic Circuitry Underlying Immunological Response to Pediatric Acute Respiratory Infection. Cell Reports 22(2) : 411-426, January 2018
- Taylor DM, Aronow BJ, Tan K, Bernt K, Salomonis N, Greene CS, Frolova A, Henrickson SE, Wells A, Pei L, Jaiswal JK, Whitsett J, Hamilton KE, MacParland SA, Kelsen J, Heuckeroth RO, Potter SS, Vella LA, Terry NA, Ghanem LR, Kennedy BC, Helbig I, Sullivan KE, Castelo-Soccio L, Kreigstein A, Herse F, Nawijn MC, Koppelman GH, Haendel M, Harris NL, Rokita JL, Zhang Y, Regev A, Rozenblatt-Rosen O, Rood JE, Tickle TL, Vento-Tormo R, Alimohamed S, Lek M, Mar JC, Loomes KM, Barrett DM, Uapinyoying P, Beggs AH, Agrawal PB, Chen YW, Muir AB, Garmire LX, Snapper SB, Nazarian J, Seeholzer SH, Fazelinia H, Singh LN, Faryabi RB, Raman P, Dawany N, Xie HM, Devkota B, Diskin SJ, Anderson SA, Rappaport EF, Peranteau W, Wikenheiser-Brokamp KA, Teichmann S, Wallace D, Peng T, Ding YY, Kim MS, Xing Y, Kong SW, Bönnemann CG, Mandl KD and PS White : The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution. Dev. Cell S1534-5807(19) : 30178, March 2019
- Henrickson SE, Perro M, Loughhead SM, Senman B, Stutte S, Quigley M, Alexe G, Iannacone M, Flynn MP, Omid S, Jesneck JL, Imam S, Mempel TR, Mazo IB, Haining WN and UH von Andrian : Antigen Availability Determines CD8+ T Cell-Dendritic Cell Interaction Kinetics and Memory Fate Decisions. Immunity 39(3) : 496-507, September 2013
- Ruffner MA, Henrickson SE, Chilutti M, Grundmeier R, Spergel JM and TF Brown-Whitehorn : Improving allergy office scheduling increases patient follow up and reduces asthma readmission after pediatric asthma hospitalization. Ann. Allergy Asthma Immunol. 121(5) : 561-567, Nov 2018
- Heimall JR, Hagin D, Hajjar J, Henrickson SE, Hernandez-Trujillo HS, Tan Y, Kobrynski L, Paris K, Torgerson TR, Verbsky JW, Wasserman RL, Hsieh EWY, Blessing JJ, Chou JS, Lawrence MG, Marsh RA, Rosenzweig SD, Orange JS and RS Abraham : Use of Genetic Testing for Primary Immunodeficiency Patients. J. Clin. Immunol 38(3) : 320-329, Apr 2018
- Henrickson SE, Mempel TR, Mazo IB, Artyomov MN, Zheng H, Liu B, Flynn M, Senman B, Junt T, Wong HC, Chakraborty AK and UH von Andrian : T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation. Nat. Immunol. 9(3) : 282-91, Mar 2008
- Mempel T, Henrickson SE and UH von Andrian : T-cell priming by Dendritic cells in Lymph Nodes Occurs in Three Distinct Phases. Nature 427(6970) : 154-59, Jan 2004 Notes: Highlighted by Thomson ISI as New Hot Paper in Immunology, March and November 2005; http://isi-topics.com/nhp/march-05-UlrichvonAndrian.html
- Keller MD, Pandey R, Li D, Glessner J, Tian L, Henrickson SE, Chinn IK, Monaco-Shawver, Heimall J, Hou C, Otieno FG, Jyonouchi S, Calabrese L, van Montfrans J, Orange JS and H Hakonarson. : Mutation in IRF2BP2 is responsible for a familial form of common variable immunodeficiency disorder. J. Allergy Clin. Immunol. 138(2) : 544-50, March 2016
- Lawless D, Geier CB, Farmer JR, Lango HA, Thwaites D, Atschekzei F, Brown M, Buchbinder D, Burns SO, Butte MJ, Csomos K, Deevi SVV, Egner W, Ehl S, Eibl MM, Fadugba O, Foldvari Z, Green DM, Henrickson SE, Holland SM, John T, Klemann C, Kujjpers TW, Moreira F, Piller A, Rayner-Matthews P, Romberg ND, Sargur R, Schmidt RE, Schroder C, Schuetz C, Sharapova SO, Smith KGC, Sogkas G, Speckmann C, Stirrups K, Thrasher AJ, Wolf HM, Notarangelo LD, Anwar R, Boyes J, Ujhazi B, NIHR BioResource-Rare Disease Consortium, Thaventhiran, Walter JE and S Savic : Prevalence and clinical challenges among adult primary immunodeficiency patients with RAG deficiency. J. Allergy Clin. Immunol. 141(6) : 2303, June 2018
- Henrickson S and D Altshuler : Risk and Return for the Clinician Scientist. Sci. Transl. Med. 4(135) : doi: 10.1126, May 2012 Notes: online pub
- Henrickson SE and JR Treat : Topical cidofovir for recalcitrant verrucae in SCID patients post hematopoetic stem cell transplant. Pediatric Dermatology 34(1) : e24-e25, October 2017
- Henrickson SE, Walter JE, Quinn C, Kanakry JA, Bardakjian T, Dimitrova D, Ujhazi B, Csomos K, Bosticardo M, Dobbs K, Nasrallah M, Notarangelo LD, Holland SM and O Fadugba. : Adult-Onset Myopathy in a Patient with Hypomorphic RAG2 Mutations and Combined Immune Deficiency. J. Clin. Immunol. 38(6) : 642-645, Aug 2018