Ahmed Diab, PhD

Selected Publications

• Miller ZA, Muthuswami S, Mueller A, Ma RZ, Sywanycz SM, Naik A, Huang L, Brody RM, Diab A, Carey RM, Lee RJ. : GLUT1 inhibitor BAY-876 induces apoptosis and enhances anti-cancer effects of bitter receptor agonists in head and neck squamous carcinoma cells Cell Death Discov 10(1):339 July 2024
• Malay K. Sannigrahi, Lovely Raghav, Ahmed Diab, Devraj Basu : The imprint of viral oncoproteins on the variable clinical behavior among human papilloma virus-related oropharyngeal squamous cell carcinomas Tumour Virus Research November 2024
• Thirimanne HN, Wu F, Janssens DH, Swanger J, Diab A, Feldman H, Amezquita RA, Gottardo R, Paddison PJ, Henikoff S, Clurman BE : Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations Elife 11 : e74338, Feb 2022
• Diab A, Gem H, Swanger J, Kim HY, Smith K, Zou G, Raju S, Kao m, Fitzgibbon M, Loeb KR, Rodriquez CP, Mendez E, Galloway DA, Sidorova JM, Clurman BE : FOXM1 drives HPV+ HNSCC sensitivity to WEE1 inhibition Proc Natl Acad Sci U S A 117(45) : 28287-28296, Nov 2020
• Diab A, Kao M, Kehrli K, Kim HY, Sidorova J, Mendez E : Multiple Defects Sensitize p53-Deficient Head and Neck Cancer Cells to the WEE1 Kinase Inhibition Mol Cancer Res 17(5) : 1115-1128, May 2019
• Mendez E, Rodriquez CP, Kao MC, Raju S, Diab A, Harbison RA, Konnick EQ, Mugundu GM, Santana-Davila R, Martins R, Futran ND, Chow LQM : A Phase I Clinical Trial of AZD1775 in Combination with Neoadjuvant Weekly Docetaxel and Cisplatin before Definitive Therapy in Head and Neck Squamous Cell Carcinoma Clin Cancer Res 24(12) : 2740-2748, Jun 2018
• Diab A, Foca A, Zoulim F, Durantel D, Andrisani O : The diverse functions of the hepatitis B core/capsid protein (HBc) in the viral life cycle: Implications for the development of HBc-targeting antivirals Antiviral Res 149 : 211-220, Jan 2018
• Diab A, Foca A, Fusil F, Lahlali T, Jalaguier P, Amirache F, N'Guyen L, Isorce N, Cosset FL, Zoulim F, Andrisani O, Durantel D : Polo-like-kinase 1 is a proviral host factor for hepatitis B virus replication Hepatology 66(6) : 1750-1765, Dec 2017
• Fan H, Cui Z, Zhang H, Mani SK, Diab A, Lefrancois L, Fares N, Merle P, Andrisani O : DNA demethylation induces SALL4 gene re-expression in subgroups of hepatocellular carcinoma associated with Hepatitis B or C virus infection Oncogene 36(17) : 2435-2445, Apr 2017
• Mani SK, Zhang H, Diab A, Pascuzzi PE, Lefancois L, Fares N, Bancel B, Merle P, Andrisani O : EpCAM-regulated intramembrane proteolysis induces a cancer stem cell-like gene signature in hepatitis B virus-infected hepatocytes J Hepatol 65(5) : 888-898, Nov 2016