Native stem cell transcriptional circuits define cardinal features of high-risk leukemia.

Wang Q, Boccalatte F, Xu J, Gambi G, Nadorp B, Akter F, Mullin C, Melnick AF, Choe E, McCarter AC, Jerome NA, Chen S, Lin K, Khan S, Kodgule R, Sussman JH, Pölönen P, Rodriguez-Hernaez J, Narang S, Avrampou K, King B, Tsirigos A, Ryan RJH, Mullighan CG, Teachey DT, Tan K, Aifantis I, Chiang MY. J Exp Med. 2025 Apr 7;222(4):e20231349. doi: 10.1084/jem.20231349. Epub 2025 Feb 19. PMID: 39969525