Doris A. Stoffers, MD, PhD
Doris A. Stoffers is a Professor of Medicine and Director of the Penn Diabetes Research Center Islet Cell Biology Core. She has extensive experience in the functional and morphological phenotyping of pancreatic islets. Working together with the Co-Director Franz Matschinsky, she oversees the strategic direction of the ICBC and is responsible for all aspects of governance.
Nicolai Doliba, DSc, PhD
Dr. Nicolai Doliba is a Research Associate Professor in the Department of Biochemistry and Biophysics and Technical Director of the Islet Cell Biology Core of the Penn Diabetes Research Center. He manages all aspects of core operation. Dr. Doliba has twenty six years of experience with islet perifusion, respirometry techniques and calcium imaging. He meets with new users to develop strategies and experimental protocols to apply to their research. Dr. Doliba also organizes workshops and provides training in a wide range of Core services including Ca2+ fluorescence and Seahorse. He has a wealth of experience characterizing the function of human islets from normal, T1D and T2D donors obtained from Dr. Naji’s Islet Resource Center at the University of Pennsylvania, as evidenced by numerous collaborative publications.
Andrea Rozo, PhD
Dr. Andrea Rozo is the Assistant Technical Director of the Islet Core. Dr. Rozo assists Dr. Doliba in all aspects of core operation. She is responsible for invoicing and billing as well as most other administrative aspects required in the Islet Core. Dr. Rozo works with Dr. Doliba to meet with and advise prospective, new, and current core users and she provides training. In addition to her administrative functions, she has developed specific expertise in calcium imaging and the generation and investigation of pseudoislet aggregates.
Toshinori Hoshi, PhD
Toshinori Hoshi, PhD is a Professor of Physiology and the newest member of the ICBC. He is an electrophysiologist with experience in microelectrode intracellular, extracellular, patch clamp, Ca2+ and optical Vm measurements. He has investigated a range of cell types, including vertebrate and invertebrate neurons and muscle cells, brain slices, synaptosomes, secretory cells (chromaffin cells, GH3/4 cells, PC12 cells) and iPS-derived cardiac cells.
Wei Qin, BS
Wei Qin is a Research Specialist for the Penn DRC Islet Cell Biology Core. She has 21 years of experience in procedures of rat and mouse islet isolation, tissue culture, islet cell dispersion and metabolic and secretory functional testing. She supports Dr. Doliba in the execution of islet perifusion and respirometry experiments. Wei masters all procedures associated with islet cell isolation, culture and functional testing.
Jeffrey Roman, BSE
Jeffrey Roman is a Research Specialist in the Department of Biochemistry and Biophysics. He is an expert with the Agilent Seahorse Bioanalyzer and helps with user trainings. He has also become proficient in perfusion techniques and the analysis of hormone secretion.
Qing Liu is a part time Research Specialist for the Penn DRC Islet Cell Biology Core. She has 6 years of experience in procedures of rat and mouse islet isolation, tissue culture, and metabolic and secretory functional testing. She is also involved in sample preparation and analysis of hormone secretion.