June 11, 2019

Dr. Katalin Susztak is the Keynote Speaker at this year's ERA-EDTA) meeting in Budapest, Hungary

Katalin Susztak

Congratulations to Dr. Katalin Susztak for being a keynote speaker at the nnual Meeting of the European Renal Association-European Dialysis and Transplantation (ERA-EDTA) meeting.

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Circadian Mechanism May Not Be Driver Behind Compound Linked to Obesity and Diabetes

May 21, 2019

Mitch Lazar, MD, PhD

SR9009 is a compound that can lead to a wide range of health benefits in animals, including reduced risk of obesity and type 2 diabetes. Until now, researchers – and companies that sell the compound for human use in the form of a nutraceutical – have attributed the effects to SR9009’s role in altering the body’s circadian clock, specifically its work through proteins called REV-ERBS that link metabolism and circadian rhythm. However, in a first-of-its-kind study from Penn Medicine, published today in PNAS, researchers found that SR9009 can effect cell growth and metabolic function without the involvement of REV-ERBs.

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