PIs |
Study Title |
Penn Rodebaugh Diabetes Center Trials |
Andrea Kelly, MD, MSCE & Michael Rickels, MD, MS |
Determination of Beta-Cell Responsiveness to the Incretin Hormones GLP-1 and GIP in Cystic Fibrosis |
| Andrea Kelly, MD, MSCE & Michael Rickels, MD, MS |
Emergence and Progression of Abnormal Glucose Tolerance in Cystic Fibrosis |
| Andrea Kelly, MD, MSCE & Michael Rickels, MD, MS |
Effects of GLP-1 Agonist Therapy on Insulin Secretion in Adults with Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a randomized, open-label, cross-over trial |
| Ali Naji, MD & Michael Rickles, MD, MS |
A Phase 1/2 Study to Evaluate the Safety, Tolerability, and Efficacy of VX-880 in
Subjects Who Have Type 1 Diabetes Mellitus with Impaired Hypoglycemic
Awareness and Severe Hypoglycemia |
| Michael Rickels, MD, MS |
A phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of 400 mg twice a day oral ladarixin in patients with new-onset type 1 diabetes and a low residual β-cell function at baselinel |
| Michael Rickels, MD, MS |
Effect of Hybrid Closed-Loop Insulin Delivery on Glucose Counterregulation in Long Standing Type 1 Diabetes: A Proof of Concept, Mechanistic, Single-Arm Clinical Trial |
| Michael Rickels, MD, MS |
Automated Insulin Delivery in Elderly with Type 1 Diabetes (AIDE T1D): A Randomized Cross-over Trial Evaluating Automated Insulin Delivery Technologies on Hypoglycemia and Quality of Life in Elderly Adults with Type 1 Diabetes |
| Michael Rickels, MD, MS |
Glycemic Variability and Fluctuations in Cognitive Status in Adults with Type I Diabetes (GluCog) |
| Michael Rickels, MD, MS |
Adrenergic Contribution To Glucose Counterregulation In Islet Transplantation |
Michael Rickels, MD, MS |
Effect of Real-Time Continuous Glucose Monitoring on Glucose Counterregulation in Long Standing Type 1 Diabetes |
Mark Schutta, MD |
Epidemiology of Diabetes Interventions and Complications Study (EDIC STUDY) |
Penn Bone Center Trials |
| Felix Wehrli, PhD |
Bone Water and Mineralization Measured by Nuclear Magnetic Resonance |
Penn Metabolic Medicine Trials |
| Anastastia Amaro, MD |
A Prospective, Randomized, Double-Blind, Sham- Controlled, Multi-Center Pivotal Study to Evaluate the Efficacy and Safety of Duodenal Mucosal Resurfacing Using the Revita® System in Subjects with Type 2 Diabetes on Insulin therapy |
| Kelly Allison, PhD |
Meal Timing and Metabolism Study |
| Zoltan P. Arany, M.D., Ph.D., Michael R. Rickels, MD., MS |
Investigation of the Effect of Branched Chain Amino Acids on Fat-Induced Insulin Resistance in Healthy Adults |
David Merrick, MD, PhD |
Human Metabolic Tissue Bank |
Penn Pituitary Center Trials |
| Peter Snyder, MD |
A Randomized, Controlled, Multi-Center Study to Evaluate the Safety and Efficacy of Paltusotine in Subjects with Acromegaly Treated with Long-acting Somatostatin Receptor Ligands |
Penn Thyroid Center Trials |
Anne Cappola, MD, MS |
Ghrelin Plus Resistance Training in Frail Elderly Study |
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