Molecular, Genetic, and Behavioral Studies of Somatosensation

Research in the Luo lab is aimed at understanding the neurobiology of somatosensation. Broadly speaking, the lab uses the mouse as a model organism to focus on the following questions:

  • What are the functional circuits governing the expression of touch, pain, and itch behaviors, and what are the molecular and cellular mechanisms underlying these circuits?
  • What salient molecular, behavioral, and cognitive features allow for the differentiation between responses to pain and itch?
  • How is somatosensory information coded and conveyed at anatomical, molecular, and circuit levels?
  • What molecular and circuit level changes are associated with the manifestation of pathological conditions of pain often seen in human disease?
  • What are the molecular and cellular mechanisms regulating the development of somatosensory circuits?

Our work employs a wide variety of cellular and molecular techniques, mouse genetic tools, mouse behavior assays, and physiological recordings to help us answer these questions.

Special Announcement Heading

News and Announcements

  • Friday, March 15, 2024

    March 2023 -- Congratulations to Dr. Mayank Gautam on getting his manuscript accepted to Nature Communications!!

  • Friday, December 1, 2023

    December 2023 -- Welcome to Caitlin Cronen and Ebenezer Simpson on joining the lab!

  • Tuesday, September 5, 2023

    Our very own Suna Cranfill successfully defended her thesis.  Congratulations to Dr. Cranfill!!