Publications

Primary Papers

Zhu, Yueyao, Shuixing Li, Alexa Jaume, Riddhi Atul Jani, Cédric Delevoye, Graça Raposo, and Michael S. Marks. “Type II Phosphatidylinositol 4-Kinases Function Sequentially in Cargo Delivery from Early Endosomes to Melanosomes.” Journal of Cell Biology 221, no. 11 (September 28, 2022): e202110114. https://doi.org/10.1083/jcb.202110114.

working model of PI4Kinases on endosomal tubules
Figure 9H. Working model (see paper for full description).

See the related paper from the Raposo lab:

Jani, Riddhi Atul, Aurélie Di Cicco, Tal Keren-Kaplan, Silvia Vale-Costa, Daniel Hamaoui, Ilse Hurbain, Feng-Ching Tsai, et al. “PI4P and BLOC-1 Remodel Endosomal Membranes into Tubules.” Journal of Cell Biology 221, no. 11 (September 28, 2022): e202110132. https://doi.org/10.1083/jcb.202110132.

Dennis, Megan K., Adriana R. Mantegazza, Olivia L. Snir, Danièle Tenza, Amanda Acosta-Ruiz, Cédric Delevoye, Richard Zorger, et al. “BLOC-2 Targets Recycling Endosomal Tubules to Melanosomes for Cargo Delivery.” Journal of Cell Biology 209, no. 4 (May 25, 2015): 563–77. https://doi.org/10.1083/jcb.201410026.

Microscope images of BLOC-2 showing recycling endosomal tubules delivering cargo to maturing melanosomes
Figure 8A-C. BLOC-2 facilitates contacts of recycling endosomal tubules with maturing melanosomes.

 

Reviews

Le, Linh, Julia Sirés-Campos, Graça Raposo, Cédric Delevoye, and Michael S Marks. “Melanosome Biogenesis in the Pigmentation of Mammalian Skin.” Integrative and Comparative Biology 61, no. 4 (October 1, 2021): 1517–45. https://doi.org/10.1093/icb/icab078.

working model of intracellular tracking during melanosome biogenesis
Figure 3. Working model of intracellular trafficking during melanosome biogenesis (see paper for full description).

Bowman, Shanna L., Jing Bi-Karchin, Linh Le, and Michael S. Marks. “The Road to Lysosome-Related Organelles: Insights from Hermansky-Pudlak Syndrome and Other Rare Diseases.” Traffic 20, no. 6 (2019): 404–35. https://doi.org/10.1111/tra.12646.

HPS complexes and mechanisms of cargo delivery to melanosomes
Figure 3. HPS complexes and mechanisms of cargo delivery to melanosomes (see paper for full description).