Publications

Selected Publications

Sinha N, Zhou DJ, Morgan VL, Englot DJ, Bonilha L, Brázdil M, He X, Masumoto R, Cao Q, O'Brien TJ, Wu C, Kaestner E, McDonald C, Gleichgerrcht E, McGonigal A, Davis KA. Intracranial electroencephalographic connectivity analysis to localize epileptogenic networks: Systematic review and meta-analysis from ILAE Epilepsy Surgery Networks Task Force. Epilepsia. 2026 Mar 2;. doi: 10.1002/epi.70168. PubMed PMID: 41770259.

*Xu Z, Scheid BH, Conrad EC, Davis KA, Ganguly T, Gelfand MA, Gugger JJ, Jiang X, LaRocque JJ, Ojemann WKS, Sinha SR, Waldman GJ, Wagenaar J, **Sinha N, **Litt B. Annotating neurophysiologic data at scale with optimized human input. J Neural Eng. 2025 Jul 3;22(4). doi: 10.1088/1741-2552/ade402. PubMed PMID: 40505672; PubMed Central PMCID: PMC12223546. **co-senior authors, *co-mentored in NeuroBridge and Litt Labs.

Goldblum Z, Xu Z, Shi H, Orzechowski P, Spence J, Davis KA, Litt B, Sinha N, Wagenaar J. Pennsieve: A Collaborative Platform for Translational Neuroscience and Beyond. Sci Data. 2025 Nov 19;12(1):1834. doi: 10.1038/s41597-025-06075-5. PubMed PMID: 41261152; PubMed Central PMCID: PMC12630885.

Sun C, Jing J, Turley N, Alcott C, Kang WY, Cole AJ, Goldenholz DM, Lam A, Amorim E, Chu C, Cash S, Junior VM, Gupta A, Ghanta M, Nearing B, Nascimento FA, Struck A, Kim J, Sartipi S, Tauton AM, Fernandes M, Sun H, Bayas G, Gallagher K, Wagenaar JB, Sinha N, Lee-Messer C, Silvers CT, Gunapati B, Rosand J, Peters J, Loddenkemper T, Lee JW, Zafar S, Westover MB. Harvard Electroencephalography Database: A comprehensive clinical electroencephalographic resource from four Boston hospitals. Epilepsia. 2025 Sep;66(9):3411-3425. doi: 10.1111/epi.18487. Epub 2025 Jun 4. PubMed PMID: 40464151; PubMed Central PMCID: PMC12455399.

Sinha N, Lucas A, Adamiak Davis K. From data to decision: Scaling artificial intelligence with informatics for epilepsy management.  Clin Transl Med. 2024 Dec;14(12):e70108. doi: 10.1002/ctm2.70108. PubMed PMID: 39673123; PubMed Central PMCID: PMC11645443.

*Gallagher RS, *Sinha N, Pattnaik AR, Ojemann WKS, Lucas A, LaRocque JJ, Bernabei JM, Greenblatt AS, Sweeney EM, Cajigas I, Chen HI, Davis KA, Conrad EC, Litt B. The sixth sense: how much does interictal intracranial EEG add to determining the focality of epileptic networks? Brain Commun. 2024;6(5):fcae320. doi: 10.1093/braincomms/fcae320. eCollection 2024. PubMed PMID: 39440305; PubMed Central PMCID: PMC11495218. *co-first authors

*Lucas A, Scheid BH, Pattnaik AR, Gallagher R, Mojena M, Tranquille A, Prager B, Gleichgerrcht E, Gong R, Litt B, Davis KA, Das S, Stein JM, Sinha N. iEEG-recon: A fast and scalable pipeline for accurate reconstruction of intracranial electrodes and implantable devices. Epilepsia.2024 Mar;65(3):817-829. doi: 10.1111/epi.17863. Epub 2024 Jan 10. PubMed PMID: 38148517; PubMed Central PMCID: PMC10948311 *co-mentored in NeuroBridge and Davis Labs.

Sinha N, Duncan JS, Diehl B, Chowdhury FA, de Tisi J, Miserocchi A, McEvoy AW, Davis KA, Vos SB, Winston GP, Wang Y, Taylor PN.Intracranial EEG Structure-Function Coupling and Seizure Outcomes After Epilepsy Surgery. Neurology. 2023 Sep 26;101(13):e1293-e1306. doi: 10.1212/WNL.0000000000207661. Epub 2023 Aug 31. PubMed PMID: 37652703; PubMed Central PMCID: PMC10558161.

Sinha N, Gugger JJ. Toward a Patient-Specific Readout of Neurodegeneration: The Case for Spatial Normative Modeling in Alzheimer Disease. Neurology. 2023 Jun 13;100(24):1125-1126. doi: 10.1212/WNL.0000000000207280. Epub 2023 May 1. PubMed PMID: 37127354.

*Gugger JJ, *Sinha N, Huang Y, Walter AE, Lynch C, Kalyani P, Smyk N, Sandsmark D, Diaz-Arrastia R, Davis KA. Structural brain network deviations predict recovery after traumatic brain injury. Neuroimage Clin. 2023;38:103392. doi: 10.1016/j.nicl.2023.103392. Epub 2023 Mar 30. PubMed PMID: 37018913; PubMed Central PMCID: PMC10122019. *co-first authors

Sinha N. Localizing epileptogenic tissues in epilepsy: are we losing (the) focus? Brain. 2022 Nov 21;145(11):3735-3737. doi: 10.1093/brain/awac373. PubMed PMID: 36412515; PubMed Central PMCID: PMC10200283.

*Bernabei JM, *Sinha N, Arnold TC, Conrad E, Ong I, Pattnaik AR, Stein JM, Shinohara RT, Lucas TH, Bassett DS, Davis KA, Litt B. Normative intracranial EEG maps epileptogenic tissues in focal epilepsy. Brain. 2022 Jun 30;145(6):1949-1961. doi: 10.1093/brain/awab480. PubMed PMID: 35640886; PubMed Central PMCID: PMC9630716. *co-first authors

Sinha N, Johnson GW, Davis KA, Englot DJ. Integrating Network Neuroscience Into Epilepsy Care: Progress, Barriers, and Next Steps. Epilepsy Curr. 2022 Sep-Oct;22(5):272-278. doi: 10.1177/15357597221101271. eCollection 2022 Sep-Oct. Review. PubMed PMID: 36285209; PubMed Central PMCID: PMC9549227.

Sinha N, Joshi RB, Sandhu MRS, Netoff TI, Zaveri HP, Lehnertz K. Perspectives on Understanding Aberrant Brain Networks in Epilepsy. Front Netw Physiol. 2022;2:868092. doi: 10.3389/fnetp.2022.868092. eCollection 2022. PubMed PMID: 36926081; PubMed Central PMCID: PMC10013006.

Sinha N, Davis KA. Mapping Epileptogenic Tissues in MRI-Negative Focal Epilepsy: Can Deep Learning Uncover Hidden Lesions?  Neurology.2021 Oct 19;97(16):754-755. doi: 10.1212/WNL.0000000000012696. Epub 2021 Sep 14. PubMed PMID: 34521690.

Sinha N, Peternell N, Schroeder GM, de Tisi J, Vos SB, Winston GP, Duncan JS, Wang Y, Taylor PN. Focal to bilateral tonic-clonic seizures are associated with widespread network abnormality in temporal lobe epilepsy. Epilepsia. 2021 Mar;62(3):729-741. doi: 10.1111/epi.16819. Epub 2021 Jan 21. PubMed PMID: 33476430; PubMed Central PMCID: PMC8600951.

Sinha N, Wang Y, Moreira da Silva N, Miserocchi A, McEvoy AW, de Tisi J, Vos SB, Winston GP, Duncan JS, Taylor PN. Structural Brain Network Abnormalities and the Probability of Seizure Recurrence After Epilepsy Surgery. Neurology. 2021 Feb 2;96(5):e758-e771. doi: 10.1212/WNL.0000000000011315. Epub 2020 Dec 22. PubMed PMID: 33361262; PubMed Central PMCID: PMC7884990.

Sinha N, Wang Y, Dauwels J, Kaiser M, Thesen T, Forsyth R, Taylor PN. Computer modelling of connectivity change suggests epileptogenesis mechanisms in idiopathic generalised epilepsy. Neuroimage Clin. 2019;21:101655. doi: 10.1016/j.nicl.2019.101655. Epub 2019 Jan 11. PubMed PMID: 30685702; PubMed Central PMCID: PMC6356007.

Sinha N, Dauwels J, Kaiser M, Cash SS, Westover MB, Wang Y, Taylor PN. Reply: Computer models to inform epilepsy surgery strategies: prediction of postoperative outcome. Brain. 2017 May 1;140(5):e31. doi: 10.1093/brain/awx068. PubMed PMID: 28334902; PubMed Central PMCID: PMC10448005.

Sinha N, Dauwels J, Kaiser M, Cash SS, Brandon Westover M, Wang Y, Taylor PN. Predicting neurosurgical outcomes in focal epilepsy patients using computational modelling. Brain. 2017 Feb;140(2):319-332. doi: 10.1093/brain/aww299. Epub 2016 Dec 23. PubMed PMID: 28011454; PubMed Central PMCID: PMC5278304.

Sinha N, Maszczyk T, Zhang Wanxuan, Tan J, Dauwels J. EEG hyperscanning study of inter-brain synchrony during cooperative and competitive interaction. 2016 IEEE International Conference on Systems, Man, and Cybernetics (SMC). 2016 IEEE International Conference on Systems, Man, and Cybernetics (SMC); ; Budapest, Hungary. IEEE; c2016.

Taylor PN, Thomas J, Sinha N, Dauwels J, Kaiser M, Thesen T, Ruths J. Optimal control based seizure abatement using patient derived connectivity. Front Neurosci. 2015;9:202. doi: 10.3389/fnins.2015.00202. eCollection 2015. PubMed PMID: 26089775; PubMed Central PMCID: PMC4453481.