The O'Rourke Laboratory
Welcome to the O'Rourke Laboratory! Located in Perelman South 8th Floor, alongside the Parker Institute for Cancer Immunotherapy, the O'Rourke Lab is dedicated to advancing treatment options for glioblastoma.
Glioblastoma (GBM), glioma grade IV, is a devastating cancer with an annual incidence of 3.19/100,000 individuals per year (~10,000) and a median survival of 14.6 months following standard-of-care surgery, radiotherapy, and chemotherapy. Few advances in treatment have been realized over the past 20 years, and 2-year survival remains close to 25%. We are developing novel methods for treating GBM and improving the outcomes of patients with this devastating disease. Our research focuses several areas of immuno-oncology, supported by model establishment and development. Dr. O'Rourke's position in the University of Pennsylvania Brain and Spinal Cord Tumor Program provides our group with access to significant tumor tissue resources, providing a wide variety of GBM models for our research.
We want to congratulate all of our summer fellowship awardees:
Thilan Tudor: 2020 Guggenheim Summer Research Fellow
Oliver Tang: 2020 NREF Medical Student Summer Research Fellow
Madeline Mandell: 2020 Penn Undergraduate Research Mentorship Program Fellow
Our clinical team has multiple ongoing clinical trials for GBM. For clinical questions, please call 215-662-3487.
Post-Doctoral Research Position Available, Inquire below
The O'Rourke Lab has a Post-Doctoral Research Position Open. If you are interested please contact Zev Binder by email: firstname.lastname@example.org, or by phone: (215) 573-0837.
Penn Center for Precision Medicine’s 3rd Annual Symposium
October 30, 2019 8:00 am – 3:00 pm; Smilow - Rubenstein Auditorium
Dear colleagues, It gives me great pleasure to announce that registration is open for the Penn Center for Precision Medicine’s 3rd Annual Symposium. Please join us to hear about precision medicine related initiatives underway at Penn Medicine, as well as and learn about the exciting research and implementation projects supported by PCPM. DATE: October 30, 2019 TIME: 8:00 am – 3:00 pm LOCATION: Smilow - Rubenstein Auditorium Please register using the link below: https://www.eventbrite.com/e/penn-center-for-precision-medicine-3rd-annual-symposium-tickets-72249330693?aff=ebdssbdestsearch Information on the Penn Center for Precision Medicine can be found by clicking on: https://www.med.upenn.edu/pcpm/ Hope to see you there! David B. Roth, MD, PhD Director, Penn Center for Precision Medicine
From Radiation Oncology Seminar Series:
Thursday, 01/30/2020, 12-1pm, SCTR 8-146
E. Antonio Chiocca, MD, PhD Harvey W. Cushing Professor of Neurosurgery Harvard Medical School Neurosurgeon-in-Chief and Chairman, Department of Neurosurgery Co-Director, Institute for the Neurosciences Brigham and Women's / Faulkner Hospital Surgical Director, Center for Neuro-oncology Dana-Farber Cancer Institute