The O'Rourke Laboratory
Welcome to the O'Rourke Laboratory! Located in Perelman South 8th Floor, alongside the Parker Institute for Cancer Immunotherapy, the O'Rourke lab is dedicated to advancing treatment options for glioblastoma.
Glioblastoma (GBM), glioma grade IV, is a devastating cancer with an annual incidence of 3.19/100,000 individuals per year (~10,000) and a median survival of 14.6 months following standard-of-care surgery, radiotherapy, and chemotherapy. Few advances in treatment have been realized over the past 20 years, and 2-year survival remains close to 25%. We are developing novel methods for treating GBM and improving the outcomes of patients with this devastating disease. Our research focuses several areas of immuno-oncology, supported by model establishment and development. Dr. O'Rourke's position in the University of Pennsylvania Brain and Spinal Cord Tumor Program provides our group with access to significant tumor tissue resources, providing a wide variety of GBM models for our research.
EORTC-NCI-AACR Molecular Targets and Cancer Therapeutics Symposium
Nov 13-16, 2018
The 2018 Symposium brings together academics, scientists and pharmaceutical industry representatives from across the globe to discuss the latest innovations in drug development, target selection and the impact of new discoveries in molecular biology.
Society for Neuro-Oncology Annual Meeting
Nov 15-18, 2018
23rd Annual Meeting and Education Day