Assistant Professor, Bethune Cookman University

Education

• Research mentor: Aalim Weljie, PhD; University of Pennsylvania

• Teaching mentor: Derrick Swinton, PhD; Lincoln University

Research Topic: Metabolomics

Metabolomics is an emerging section of systems biology that incorporates high-resolution mass spectrometry (HRMS) and nuclear magnetic resonance (NMR) with multivariate statistical analysis for identification and quantification of metabolites in biological systems. The overarching goal of my work involves developing a novel hyphenated UPLC/MS-NMR workflow and bioinformatics. The focus of my work includes identifying perturbations in metabolic homeostasis due to altered circadian output in sleep deprivation and biomarker discovery in Sickle cell disease.

Courses Taught:

• CHEM 325 – Analytical Chemistry for Chemistry Majors; Course Instructor; Rutgers University; Camden, NJ

 
Publications

Journal Publications 

• Bolden, S., Boateng, C.A., Zhu, X.Y., Etukala, J.R., Eyunni, S.K., Jacob, M.R., Khan, S.I., Walker, L.A., Ablordeppey, S.Y., CoMFA studies and in vitro evaluation of some 3-substituted benzylthio quinolinium salts as anticryptococcal agents, Bioorganic & Medicinal Chemistry (2013).

• Bolden, S., Zhu, X.Y., Etukala, J.R.; Boateng, C., Mazu, T., Flores-Rozas, H., Jacob, M.R., Khan, S.I., Ablordeppey, S.Y., Structure-Activity Relationship (SAR) and Preliminary Mode of Action Studies of 3-Substituted Benzylthioquinolinium Iodide as Anti-opportunistic Infection Agents, European Journal of Medicinal Chemistry (2013). 

Contact info:

Sidney Bolden, Jr., Ph.D. 
Postdoctoral Fellow 
Pharmacology Department
Perelman School of Medicine
University of Pennsylvania 

E-mail: sbold@mail.med.upenn.edu