Clinical Transcriptomics in Systemic Vasculitis (CUTIS)



The purpose of this study is to take skin biopsy samples from participants with skin (cutaneous) vasculitis to see what vasculitis is doing to the skin.

NO. You do not have to take medication to participate in the study.

Vasculitis frequently affects the skin and causes different kinds of rashes (lesions). The doctors in this study would like to describe the impact of vasculitis on the skin and to investigate the differences between the different types of skin vasculitis. The research team hopes that this study will develop information about skin vasculitis that will allow researchers to learn about the causes, the disease process and potential treatments for skin vasculitis.

  1. Patients must first have a diagnosis of the following types of isolated skin vasculitis:
    • Cryoglobulinemic vasculitis (CV)
    • Drug-induced vasculitis
    • Eosinophilic granulomatosis with polyangiitis (EGPA // Churg-Strauss)
    • Granulomatosis with polyangiitis (GPA // Wegner's)
    • IgA vasculitisIsolated cutaneous vasculitis
    • Microscopic polyangiitis (MPA)
    • Polyarteritis nodosa (PAN)
    • Urticarial vasculitis

  2. Have a cutaneous lesion (purpuric macule or papule, retiform purpura, nodule, ulcer, or urticarial) believed to be related to active vasculitis

The study only involves a one time visit, usually completed on the day of enrollment.


At the first visit, you will be asked to provide information about your medical history, the current medication you are taking for your vasculitis, and you will be asked to have a photograph taken of the skin lesions you have that are related to your vasculitis. At this initial visit, you will also be asked to provide a skin biopsy sample on a skin lesion that is between 24-36 hours old or is not older than one week. If you have more than one skin lesion, you will be asked if the doctor can take two skin biopsy samples. One will be used for this study and the other will be evaluated as part of your standard care. You will also be asked to provide blood samples for research. If you are getting newly diagnosed, you will be asked to come in 6 months later for a diagnosis confirmation.

Thank you for your interest! If you wish to learn more and sign up for the study, please contact: