University of Pennsylvania

Predoctoral Training Grant in Pharmacology

2020-2021 Trainees

Trainee Lab Mentor Research Project
Brandon Anderson  Josh Dunaief

Neuroprotective mechanisms and effects of estrogen and iron chelators on the retina

Alexander Benton   

Daniel Powell CRISPR/Cas9 Genome Targeting for the Implementation of Next Generation of CAR-T Therapies
Adrienne Jo  

Seema Bhatnagar

Role of Orexins throughout Social Defeat Stress Model and Drug Reward

Zachary Lamplugh  

Yi Fan

Reprogramming glioma microenvironment for immunotherapy
Sonia Lombroso  

Frederick Christian Bennett

Discovering Regulators of Macrophage Identity in Brain
Bridget McVeigh  

Vera Moiseenkova-Bell

Transient receptor potential mucolipin 1 (TRPML1) localization patterns and protein binding partners in Mucolipidosis type IV (ML4) mild-to-severe disease mutants 

Laura Romano Park Cho Park

Molecular synchronization of protein homeostasis by 4EBP1-PI31

Alexander Starr Kelly Jordan-Sciutto

Interrogating Mechanisms of HIV-Associated CNS Damage in Human iPSC-derived Forebrain Organoids

Alexandra Vazquez-Salgado  Kirk Wangensteen

Identifying and characterizing novel druggable targets in Hepatocellular Carcinoma

Eric Waite Klaus Kaestner

Genomic characterization of DNA double strand breaks in T2D

Alyssa Wiest Shinjae Chung

Whole brain mapping of stress-activated neurons

Veronika Yakovishina

Jeffrey Field Exploring Mechanisms of MEK Inhibitor Resistance in Malignant Peripheral Nerve Sheath Tumors by Targeting the Hippo Pathway

Former Trainees Currently Enrolled in Program

Trainee Lab Mentor Research Project
Varun Bahl

Klaus Kaestner

Regulation and function of the MEG3 locus in human β-cells
Kayla Barekat Garret FitzGerald

Exploring the role of the gut microbiome in NSAID-induced gastroenteropathy

Kryshawna Beard

David Meaney   Extracellular vesicles as biomarkers for monitoring inflammation after traumatic brain injury
Tatiana Blanchard Beatriz Carreno

Epigenetic Reprogramming to Promote Human Antigen-Specific CD8+ T cell Immunity

Marco Carpenter Elizabeth Heller

Insights Into Epigenetic Drug Memories

Eddie Chuang James Shorter

Exploring and enhancing the metazoan protein-disaggregase system to combat misfolding of FUS and TDP-43

Andrea Guzman Jim Delikatny

Synthesis and Characterization of a pH Sensitive Probe in the Near Infrared Region for Tumor Microenvironment Imaging

Michael Hart  Jim Delikatny Elucidation of the optical and therapeutic properties of near-infrared fluorescent inhibitors of choline kinase α for the treatment of lung cancers
Courtney Hong Mark L. Kahn

The molecular pathogenesis of cerebral cavernous malformations

Daniel Jacome 

Mark Sellmyer  Small Molecule Sensing of Cell-Cell Interaction
Dania Malik  Aalim Weljie

Deciphering Chronometabolic Dysfunction in Drosophila Short Sleep Models

Claire Meurice Kelly Jordan-Sciutto

Developing models to study the role of E2F1 in HIV-related synaptodendritic health

Laura Puentes Robert Mach

Evidence of PARP-1 Dependent Cytotoxic Agents with Poor Substrate Specificity for P-glycoprotein

Natalia Quijano Carde Mariella De Biasi

The Potential of GluK1-containing Kainate Receptors as Targets for Alcohol Addiction Treatment

Christopher Roselle Carl June

Investigating the role of p53 isoform regulation in the long-term persistence of chimeric antigen receptor T cells

Lindsay Roth Kelly Jordan-Sciutto/Judith Grinspan

A Role for TDP-43-Mediated Stress Granules in Antiretroviral Drug Facilitated Inhibition of Oligodendrocyte Maturation

Lauren Shaw  Daniel Powell 

Development of universal CART cells through gene engineering

Ryan von Kleeck Richard Assoian

The consequences of progerin expression on mechanosensation and arterial stiffening in Hutchinson-Gilford Progeria Syndrome

Katherine Webb Mariella De Biasia

The effect of chronic drug exposure on neuronal activity in the Medial Habenul

Khadija Wilson Benjamin Garcia

Determining the pathological mechanism of H3.3 Mutants in Neurodevelopment\