University of Pennsylvania

Predoctoral Training Grant in Pharmacology

2019-2020 Trainees

Trainee Lab Mentor Research Project
Brandon Anderson  Josh Dunaief

Neuroprotective mechanisms and effects of estrogen and iron chelators on the retina

Varun Bahl Klaus Kaestner

Regulation and function of the MEG3 locus in human β-cells

Kryshawna Beard

David Meaney/David Issadore 

Extracellular vesicles as biomarkers for monitoring inflammation after traumatic brain injury
Michael Hart Jim Delikatny

Elucidation of the optical and therapeutic properties of near-infrared fluorescent inhibitors of choline kinase α for the treatment of lung cancers

Daniel Jacome Mark Sellmyer

Small Molecule Sensing of Cell-Cell Interactions

Laura Romano Park Cho Park

Molecular synchronization of protein homeostasis by 4EBP1-PI31

Lauren Shaw Daniel Powell

Development of universal CART cells through gene engineering

Alexander Starr Kelly Jordan-Sciutto

Interrogating Mechanisms of HIV-Associated CNS Damage in Human iPSC-derived Forebrain Organoids

Alexandra Vazquez-Salgado  Kirk Wangensteen

Identifying and characterizing novel druggable targets in Hepatocellular Carcinoma

Eric Waite Klaus Kaestner

Genomic characterization of DNA double strand breaks in T2D

Katherine Webb Mariella De Biasi

The effect of chronic drug exposure on neuronal activity in the Medial Habenula

Alyssa Wiest  

Whole brain mapping of stress-activated neurons

Former Trainees Currently Enrolled in Program

Trainee Lab Mentor Research Project

Alejandro Arroyo

Jim Delikatny

Cerenkov Bioactive Imaging Agents

Kayla Barekat Garret FitzGerald

Exploring the role of the gut microbiome in NSAID-induced gastroenteropathy

Tatiana Blanchard Beatriz Carreno

Epigenetic Reprogramming to Promote Human Antigen-Specific CD8+ T cell Immunity

Marco Carpenter Elizabeth Heller

Insights Into Epigenetic Drug Memories

Eddie Chuang James Shorter

Exploring and enhancing the metazoan protein-disaggregase system to combat misfolding of FUS and TDP-43

Grace Coggins John Maris

Modulation of the Hippo pathway protein YAP as a potential route of resistance to MEK inhibition in relapsed neuroblastoma

Malcolm Daniels Harry Ischiropolous 

Neuroprotective Strategies Targeting Alpha-Synuclein in Parkinson’s Disease

Andrea Guzman Jim Delikatny

Synthesis and Characterization of a pH Sensitive Probe in the Near Infrared Region for Tumor Microenvironment Imaging

Courtney Hong Mark L. Kahn

The molecular pathogenesis of cerebral cavernous malformations

Jack Jacobs Amita Sehgal

Anandamide and sleep in Drosophila melanogaster

Lumena Louis David Weiner

Exploring IL-35 as a Potential Adjuvant in DNA Vaccines

Dania Malik  Aalim Weljie

Deciphering Chronometabolic Dysfunction in Drosophila Short Sleep Models

Claire Meurice Kelly Jordan-Sciutto

Developing models to study the role of E2F1 in HIV-related synaptodendritic health

Ross Pirnie Ian Blair

Exploration of molecular mechanisms and biomarkers of drug induced liver injury

Izmarie Poventud-Fuentes Skip Brass

Synthetic blood vessels as tools to understand hemostasis in humans

Laura Puentes Robert Mach

Evidence of PARP-1 Dependent Cytotoxic Agents with Poor Substrate Specificity for P-glycoprotein

Natalia Quijano Carde Mariella De Biasi

The Potential of GluK1-containing Kainate Receptors as Targets for Alcohol Addiction Treatment

Christopher Roselle Carl June

Investigating the role of p53 isoform regulation in the long-term persistence of chimeric antigen receptor T cells

Lindsay Roth Kelly Jordan-Sciutto/Judith Grinspan

A Role for TDP-43-Mediated Stress Granules in Antiretroviral Drug Facilitated Inhibition of Oligodendrocyte Maturation

Ryan von Kleeck Richard Assoian

The consequences of progerin expression on mechanosensation and arterial stiffening in Hutchinson-Gilford Progeria Syndrome

Amber Wang Klaus Kaestner

TRAP-seq identifies Slc7a11 as a promoter of liver regeneration following toxic injury

Khadija Wilson Benjamin Garcia

Determining the pathological mechanism of H3.3 Mutants in Neurodevelopment\