The Pennsylvania Muscle Institute:

Cytoskeletal Research @ Penn

The PMI is an interdisciplinary group of research investigators, founded to explore mechanisms of muscle function and muscle disease.

The Pennsylvania Muscle Institute:

Cytoskeletal Research @ Penn

The PMI is an interdisciplinary group of research investigators, founded to explore mechanisms of muscle function and muscle disease.

The Pennsylvania Muscle Institute:

Cytoskeletal Research @ Penn

The PMI is an interdisciplinary group of research investigators, founded to explore mechanisms of muscle function and muscle disease.

Welcome to

The Pennsylvania Muscle Institute

The PMI is an interdisciplinary group of research investigators, founded to explore mechanisms of muscle function and muscle disease. Our progress has led us to broaden our focus to include the exploration of cytoskeletal dynamics and their role in cellular functions including cell motility, intracellular transport, and organelle trafficking. Our institute is dedicated to innovative, collaborative, and cross-disciplinary research, and the application of our discoveries to the treatment of human disease.

**Please contact us via email to be added to the email listserv for updates on PMI-sponsored events.**

Events

Physiology/PMI Seminar

Sep 14, 2026 @ 03:00pm
PMI/Physiology Seminars Fall 2026
PMI/Physiology Seminars Fall 2026

PMI Special Seminar – Henry N. Higgs, PhD

Oct 5, 2026 @ 11:00am
PMI Special Events PMI Special Seminar Seminars Fall 2026
PMI Special Events PMI Special Seminar Seminars Fall 2026

Physiology/PMI/ATLE Seminar

Oct 5, 2026 @ 03:00pm
Fall 2026 At The Leading Edge - ATLE (PMI/Physiology Trainee-Invited) PMI/Physiology Seminars
Fall 2026 At The Leading Edge - ATLE (PMI/Physiology Trainee-Invited) PMI/Physiology Seminars

Physiology/PMI Seminar

Oct 26, 2026 @ 03:00pm
PMI/Physiology Seminars Fall 2026
PMI/Physiology Seminars Fall 2026

Physiology/PMI/ATLE Seminar

Nov 2, 2026 @ 03:00pm
At The Leading Edge - ATLE (PMI/Physiology Trainee-Invited) PMI/Physiology Seminars Fall 2026
At The Leading Edge - ATLE (PMI/Physiology Trainee-Invited) PMI/Physiology Seminars Fall 2026
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Publications

Beyond structure: spectroscopic imaging in cryogenic electron microscopy

2026

Role of the nonhelical tailpiece of myosin-II in regulating filament architecture and function

2026

Stiffness-induced impairment of GLUT4 trafficking in adult cardiomyocytes

2026

The mechanisms of contractile dysfunction following chronic limited platelet activation in (pro)thrombotic conditions

2026
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News

2026-2027 PMI special events

Save the dates for upcoming PMI Special Events!

Please make sure you are on the PMI events listserv to receive updates for registration, speakers,

News 2026

Please read: PMI Events and Listservs

Please see for more information on PMI event updates.

2025

Save the date – PMI Winter Symposium 2025

Save the date for our PMI Winter Symposium – Fri. Dec. 5, 2025.

More details to come — make sure you are on the PMI Seminars/events listserv to receive info for registration,

2025

Save the date for annual PMI Holiday Party

Save the date – Fri. 12/12 – for the annual PMI Holiday Party! More details to come.

2025
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