2018 Annual Retreat and Symposium - November 12, 2018

Intermediate Filaments
Cytoskeleton Mechanics, Motility, and the Nucleus

E. Michael Ostap

Arthur H. Rubenstein Auditorium,
Smilow Center for
Translational Research

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Schedule of Events




8:30 – 9:00

Smilow Commons


9:00 - 9:15

Smilow Auditorium

E. Michael Ostap, PhD - Director, Pennsylvania Muscle Institute and Professor of Physiology

Robert E. Davies Honorary Lectures

9:15 - 10:00

Smilow Auditorium

Robert D. Goldman, PhD
Northwestern University
“The roles of intermediate filaments in regulating cytoskeletal crosstalk, cell mechanics and motility”

10:00 - 10:30

Smilow Auditorium

Irena Ivanovska, PhD (Discher Lab)
University of Pennsylvania
"Nuclear rupture at sites of high curvature compromises retention of DNA repair factors"

10:30 - 11:00

Smilow Auditorium

Coffee, Posters, Vendors

11:00 - 11:45

Smilow Auditorium

A. Sue Menko, PhD
Thomas Jefferson University
"Does vimentin have distinct functions in wound repair and fibrosis?"

11:45 - 12:30

Smilow Auditorium

Sandrine Etienne-Manneville, PhD
Institut Pasteur
"Intermediate filaments in cell migration"

12:30 - 1:30

Smilow Commons

Lunch, Poster Session, and Vendors

Andrew P. Somlyo Honorary Lectures

1:30 - 2:00

Smilow Auditorium

Alison E. Patteson, PhD (Janmey Lab)
University of Pennsylvania
"Loss of vimentin intermediate filaments decreases peri-nuclear stiffness and enhances cell motility through confined spaces"

2:00 - 2:45

Smilow Auditorium

Sylvie Hénon, PhD
University of Paris, Diderot
"Role of desmin and desmin mutation in passive and active mechanical properties of myoblasts"

2:45 - 3:15

Smilow Commons

Coffee Break and Poster Session

3:15 - 3:45

Smilow Auditorium

Julie Heffler (Prosser Lab)
University of Pennsylvania
"Desmin protects cardiomyocyte nuclei from microtubule-dependent collapse"

3:45 - 4:30

Smilow Auditorium

Jan Lammerding, PhD
Cornell University
“Mutant lamins cause mechanically-induced nuclear envelope rupture, DNA damage, and DNA-PK activation in muscle”

4:30 - 5:30

Smilow Commons


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