The Pennsylvania Muscle Institute:

Cytoskeletal Research @ Penn

The PMI is an interdisciplinary group of research investigators, founded to explore mechanisms of muscle function and muscle disease.

The Pennsylvania Muscle Institute:

Cytoskeletal Research @ Penn

The PMI is an interdisciplinary group of research investigators, founded to explore mechanisms of muscle function and muscle disease.

The Pennsylvania Muscle Institute:

Cytoskeletal Research @ Penn

The PMI is an interdisciplinary group of research investigators, founded to explore mechanisms of muscle function and muscle disease.

Welcome to

The Pennsylvania Muscle Institute

The PMI is an interdisciplinary group of research investigators, founded to explore mechanisms of muscle function and muscle disease. Our progress has led us to broaden our focus to include the exploration of cytoskeletal dynamics and their role in cellular functions including cell motility, intracellular transport, and organelle trafficking. Our institute is dedicated to innovative, collaborative, and cross-disciplinary research, and the application of our discoveries to the treatment of human disease.

**Please contact us via email to be added to the email listserv for updates on PMI-sponsored events.**

Events

Cell Motility Journal Club

Jul 15, 2026 @ 12:00pm
Cell Motility Journal Club Summer 2026 Journal Club
Cell Motility Journal Club Summer 2026 Journal Club

Cell Motility Journal Club

Jul 22, 2026 @ 12:00pm
Journal Club Cell Motility Journal Club Summer 2026
Journal Club Cell Motility Journal Club Summer 2026

Cell Motility Journal Club

Jul 29, 2026 @ 12:00pm
Journal Club Cell Motility Journal Club Summer 2026
Journal Club Cell Motility Journal Club Summer 2026

Cell Motility Journal Club

Aug 12, 2026 @ 12:00pm
Journal Club Cell Motility Journal Club Summer 2026
Journal Club Cell Motility Journal Club Summer 2026

Cell Motility Journal Club

Aug 19, 2026 @ 12:00pm
Main Category Cell Motility Journal Club Summer 2026
Main Category Cell Motility Journal Club Summer 2026
View All Events

Publications

Phosphate release from myosin Va occurs after the initial powerstroke but before the secondary powerstroke associated with ADP-release

2026

Transcription and cohesin direct domain boundary spatial positioning and are linked to Friedreich’s ataxia

2026

Determination of α-Synuclein Protein Interactions by μMap Photoproximity Labeling

2026

A local solution to local load: Myo1E as a tension-responsive actuator in clathrin-mediated endocytosis

2026
View All Publications

News

2026-2027 PMI special events

Save the dates for upcoming PMI Special Events!

Please make sure you are on the PMI events listserv to receive updates for registration, speakers,

News 2026

Please read: PMI Events and Listservs

Please see for more information on PMI event updates.

2025

Save the date – PMI Winter Symposium 2025

Save the date for our PMI Winter Symposium – Fri. Dec. 5, 2025.

More details to come — make sure you are on the PMI Seminars/events listserv to receive info for registration,

2025

Save the date for annual PMI Holiday Party

Save the date – Fri. 12/12 – for the annual PMI Holiday Party! More details to come.

2025
View All News