Publications

See below for the latest publications by PMI members and their labs.

September 15, 2023
Impacts of radiation exposure, hindlimb unloading, and recovery on murine skeletal muscle cell telomere length
Foteini Mourkioti, Ph.D.
Tichy ED, Lee JH, Li G, Estep KN, Brad Johnson F, Mourkioti F. Impacts of radiation exposure, hindlimb unloading, and recovery on murine skeletal muscle cell telomere length. NPJ Microgravity. 2023 Sep 15;9(1):76. doi: 10.1038/s41526-023-00303-1. PMID: 37714858; PMCID: PMC10504369.
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September 7, 2023
Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling
Erika L. F. Holzbaur, Ph.D.
Harding, O., Holzer, E., Riley, J. F., Martens, S., & Holzbaur, E. L. F. (2023). Damaged mitochondria recruit the effector NEMO to activate NF-κB signaling. Molecular cell, 83(17), 3188–3204.e7. https://doi.org/10.1016/j.molcel.2023.08.005
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August 26, 2023
Conformation of actin subunits at the barbed and pointed ends of F-actin with and without capping proteins
Roberto Dominguez, Ph.D.
Barrie, K. R., Carman, P. J., & Dominguez, R. (2023). Conformation of actin subunits at the barbed and pointed ends of F-actin with and without capping proteins. Cytoskeleton (Hoboken, N.J.), 10.1002/cm.21770. Advance online publication. https://doi.org/10.1002/cm.21770
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August 15, 2023
Transition State of Arp2/3 Complex Activation by Actin-Bound Dimeric Nucleation-Promoting Factor
Roberto Dominguez, Ph.D.
van Eeuwen, T., Boczkowska, M., Rebowski, G., Carman, P. J., Fregoso, F. E., & Dominguez, R. (2023). Transition State of Arp2/3 Complex Activation by Actin-Bound Dimeric Nucleation-Promoting Factor. Proceedings of the National Academy of Sciences of the United States of America, 120(33), e2306165120. https://doi.org/10.1073/pnas.2306165120
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August 12, 2023
Preclinical Tendon and Ligament Models: Beyond the 3Rs (Replacement, Reduction, and Refinement) to 5W1H (Why, Who, What, Where, When, How)
Nathaniel Dyment, Ph.D., Louis J. Soslowsky, Ph.D.
Little, D., Amadio, P. C., Awad, H., Cone, S. G., Dyment, N. A., Fisher, M. B., Huang, A. H., Koch, D. W., Kuntz, A. F., Madi, R., McGilvrey, K., Schnabel, L. V., Shetye, S. S., Thomopoulos, S., Zhao, C., & Soslowsky, L. J. (2023). Preclinical Tendon and Ligament Models: Beyond the 3Rs (Replacement, Reduction, and Refinement) to 5W1H (Why, Who, What, Where, When, How). Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 10.1002/jor.25678. Advance online publication. https://doi.org/10.1002/jor.25678
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August 11, 2023
Adult human cardiomyocyte mechanics in osteogenesis imperfecta
Benjamin L. Prosser, Ph.D, Kenneth B. Margulies, M.D.
Lee, B. W., Caporizzo, M. A., Chen, C. Y., Bedi, K. C., Jr, Peyster, E. G., Prosser, B. L., Margulies, K. B., & Vite, A. (2023). Adult human cardiomyocyte mechanics in osteogenesis imperfecta. American journal of physiology. Heart and circulatory physiology, 10.1152/ajpheart.00391.2023. Advance online publication. https://doi.org/10.1152/ajpheart.00391.2023
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August 9, 2023
Origin and arrangement of actin filaments for gliding motility in apicomplexan parasites revealed by cryo-electron tomography
Yi-Wei Chang, Ph.D.
Martinez, M., Mageswaran, S. K., Guérin, A., Chen, W. D., Thompson, C. P., Chavin, S., Soldati-Favre, D., Striepen, B., & Chang, Y. W. (2023). Origin and arrangement of actin filaments for gliding motility in apicomplexan parasites revealed by cryo-electron tomography. Nature communications, 14(1), 4800. https://doi.org/10.1038/s41467-023-40520-6
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August 7, 2023
Endocytic myosin-1 is a force-insensitive, power-generating motor
E. Michael Ostap, Ph.D., Daniel Safer, Ph.D.
Pedersen, R. T. A., Snoberger, A., Pyrpassopoulos, S., Safer, D., Drubin, D. G., & Ostap, E. M. (2023). Endocytic myosin-1 is a force-insensitive, power-generating motor. The Journal of cell biology, 222(10), e202303095. https://doi.org/10.1083/jcb.202303095
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July 6, 2023
Lack of skeletal muscle contraction disrupts fibrous tissue morphogenesis in the developing murine knee
Nathaniel Dyment, Ph.D., Robert L. Mauck, Ph.D.
Tsinman, T. K., Huang, Y., Ahmed, S., Levillain, A. L., Evans, M. K., Jiang, X., Nowlan, N. C., Dyment, N. A., & Mauck, R. L. (2023). Lack of skeletal muscle contraction disrupts fibrous tissue morphogenesis in the developing murine knee. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 10.1002/jor.25659. Advance online publication. https://doi.org/10.1002/jor.25659
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July 3, 2023
Drosophila class-I myosins that can impact Left-Right asymmetry have distinct ATPase kinetics
E. Michael Ostap, Ph.D.
Báez-Cruz FA, Ostap EM. Drosophila class-I myosins that can impact Left-Right asymmetry have distinct ATPase kinetics. J Biol Chem. 2023 Jun 26:104961. doi: 10.1016/j.jbc.2023.104961. Epub ahead of print. PMID: 37380077.
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