See below for the latest publications by PMI members and their labs.
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April 18, 2025
Structure and function of vimentin in the generation and secretion of extracellular vimentin in response to inflammation
Paul A. Janmey, Ph.D.
Yuan Z, Janmey PA, McCulloch CA. Structure and function of vimentin in the generation and secretion of extracellular vimentin in response to inflammation. Cell Commun Signal. 2025 Apr 18;23(1):187. doi: 10.1186/s12964-025-02194-z. PMID: 40251523; PMCID: PMC12007377.
Long range mutual activation establishes Rho and Rac polarity during cell migration
Janis K. Burkhardt, Ph.D.
De Belly H, Gallen AF, Strickland E, Estrada DC, Zager PJ, Burkhardt JK, Turlier H, Weiner OD. Long range mutual activation establishes Rho and Rac polarity during cell migration. bioRxiv [Preprint]. 2024 Oct 2:2024.10.01.616161. doi: 10.1101/2024.10.01.616161. PMID: 40236007; PMCID: PMC11996577.
A TRPV4-dependent calcium signaling axis governs lamellipodial actin architecture to promote cell migration
Tatyana M. Svitkina, Ph.D
Iu E, Bogatch A, Deng W, Humphries JD, Yang C, Valencia FR, Li C, McCulloch CA, Tanentzapf G, Svitkina TM, Humphries MJ, Plotnikov SV. A TRPV4-dependent calcium signaling axis governs lamellipodial actin architecture to promote cell migration. bioRxiv [Preprint]. 2025 Mar 30:2025.03.28.646012. doi: 10.1101/2025.03.28.646012. PMID: 40196692; PMCID: PMC11974816.
Dynamics of β-cardiac myosin between the super-relaxed and disordered-relaxed states
E. Michael Ostap, Ph.D., Yale E. Goldman, M.D., Ph.D
Cail RC, Báez-Cruz FA, Winkelmann DA, Goldman YE, Ostap EM. Dynamics of β-cardiac myosin between the super-relaxed and disordered-relaxed states. J Biol Chem. 2025 Mar 19;301(5):108412. doi: 10.1016/j.jbc.2025.108412. Epub ahead of print. PMID: 40118457.
Clinical signatures of SYNGAP1-related disorders through data integration
Benjamin L. Prosser, Ph.D
McKee JL, Magielski JH, Xian J, Cohen S, Toib J, Harrison A, Chen C, Kim D, Rathod A, Brimble E, Fitter N, Graglia JM, Helde KA, McKeown Ruggiero S, Boland MJ, Prosser BL, Sederman R, Helbig I. Clinical signatures of SYNGAP1-related disorders through data integration. Genet Med. 2025 Mar 19:101419. doi: 10.1016/j.gim.2025.101419. Epub ahead of print. PMID: 40119723.
Ndc80 complex, a conserved coupler for kinetochore-microtubule motility, is a sliding molecular clutch
Ekaterina Grishchuk, Ph.D.
Demidov VM, Gonchar IV, Tripathy SK, Ataullakhanov FI, Grishchuk EL. Ndc80 complex, a conserved coupler for kinetochore-microtubule motility, is a sliding molecular clutch. bioRxiv [Preprint]. 2025 Mar 13:2025.03.13.643154. doi: 10.1101/2025.03.13.643154. PMID: 40161670; PMCID: PMC11952512.
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