About the RMPC

Specific Aims of the RMPC

Provide access to state-of-the-art resources and expertise for rodent metabolic studies. In many cases, the standard techniques for phenotyping rodents are not accessible to individual investigators because they require expert surgical and mouse-handling skills, specialized facilities, and/or prohibitively expensive equipment. The RMPC houses the necessary expertise, facilities (e.g., infusions space for clamps using radiolabeled isotopes), and specialized equipment (e.g., indirect calorimetry, DSI telemetry). By providing these services, the RMPC reduces these barriers and enables investigators to perform high-level metabolic studies.  

Provide individualized guidance and assistance for designing and implementing in vivo metabolic assays. A key function of the core is to make metabolic assays accessible to investigators who would otherwise not be able to perform such studies. In many cases, this involves providing guidance as to the selection of appropriate assays within the suite of services offered by the core, and we are happy to do this. 

Promote interactions and synergy with cores of IDOM and the DRC. The RMPC fosters close interactions with the Radioimmunoassay and Biomarkers Core, Islet Cell Biology Core, Transgenic Mouse Genome Editing Core, Regional Metabolomics and Fluxomics Core at Princeton in order to optimize metabolic studies in rodent models.