Resources for Trainees

Dr. Warren Pear went and tabled with the University of Pennsylvania at the 2019 Annual Biomedical Research Conference for Minority Students (ABRCMS) to let attendees know about the , and the opportunity to receive funding and support from it.

Every third Wednesday of the month, the trainees from the "Immune System Development and Regulation" and the trainees from the "Immunobiology of Normal and Neoplastic Lymphocytes" get together for lunch. For each of these meetings, there is a designated trainee speaker who presents their research and gets feedback from their peers. The director of each program, Dr. Warren Pear and Dr. Michael Cancro attend as well and provide expertise to the speakers.

In addition, trainers and other associated faculty present selected topics of interest to the trainees at these lunches. In January 2020, instructor Dr. Alexander Huang from the Division of Hematology & Oncology presented "Melanoma: An Overview" in preparation for trainees' participation in the melanoma tumor board conferences. 

• Biomedical Postdoctoral Programs
• Biomedical Graduate Studies

Penn Medicine Institute for Immunology

Abramson Cancer Center

Improved SILAC Quantification with Data-Independent Acquisition to Investigate Bortezomib-Induced Protein Degradation

Differential Integration of Transcriptome and Proteome Identifies Pan-cancer Prognostic Biomarkers.

Classes of ITD predict outcomes in AML patients treated with FLT3 inhibitors.

Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques.

Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications

mTOR has distinct functions in generating versus sustaining humoral immunity.

Commensal microbes induce serum IgA responses that protect against polymicrobial sepsis.

TAM receptors attenuate murine NK cell responses via E3 ubiquitin ligase Cbl-b

Ubiquitin Ligases and Deubiquitinating Enzymes in CD4+ T Cell Effector Fate Choice and Function

Ndfip1 restricts mTORC1 signalling and glycolysis in regulatory T cells to prevent autoinflammatory disease

Ndfip1 restricts Th17 cell potency by limiting lineage stability and proinflammatory cytokine production

Direction of Leukocyte Polarization and Migration by the Phosphoinositide-Transfer Protein TIPE2

Effective adoptive immunotherapy of triple-negative breast cancer by folate receptor-alpha redirected CAR T cells is influenced by surface antigen expression level.

The Impact of Chemotherapy, Radiation and Epigenetic Modifiers in Cancer Cell Expression of Immune Inhibitory and Stimulatory Molecules and Anti-Tumor Efficacy

The HMG transcription factor TOX induces a transcriptional and epigenetic program of CD8+ T cell exhaustion in chronic infection and cancer

Regulation of inflammation and tumorigenesis by the TIPE family of phospholipid transfer proteins

Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18

Inactivation of interferon receptor promotes the establishment of immune-privileged tumor microenvironment

Triggering ubiquitination of IFNAR1 protects tissues from inflammatory injury

Isotopic Labeling and Quantitative Proteomics of Acetylation on Histones and Beyond

Proteome-wide acetylation dynamics in human cells

SATB1 Expression Governs Epigenetic Repression of PD-1 in Tumor-Reactive T Cells

Gr1-/low CD11b-/low MHCII+ myeloid cells boost T cell anti-tumor efficacy

Function of Human Tumor-Infiltrating Lymphocytes in Early Stage Non-Small Cell Lung Cancer