Resources for Trainees
Events for Trainers and Trainees
On every other Thursday, the trainees from the "Immune System Development and Regulation" and the trainees from the "Immunobiology of Normal and Neoplastic Lymphocytes" get together for lunch. For each of these meetings, there is a designated trainee speaker who presents their research and gets feedback from their peers and the program directors. Below is a list of our 2025-2026 meetings:
September 2025
Trainee: Isabel Breuer: “JNK signaling and mRNA stability”
October 2025
Trainee: Austin Good, MD, PhDL "Investigating mechanisms of PARP inhibitor resistance in BRCA1/2-mutated PDAC using patient-derived organoid models”
November 2025
Trainee: Stefan Lundh: "TOX is Required to Sustain the CD4 T Cell Response to Chronic LCMV Infection"
Faculty: Sydney Shaffer, MD, Ph.D
December, 2025
Trainee: Molly Bunkofske, PhD
Trainee: Cordelia McGehee, MD, Ph.D
January 2026
Trainee: Matt Schuelke, MD, PhD
February 2026
Trainee: Sean Callahan, PhD
March 2026
Trainee: Daniel Hwang, PhD
Trainee: Lukas Ronner, MD, MSCR
Aril 2026
Trainee: Trainee: Alberto Guerra, MD, PhD
Trainee: Monica Pomaville, MD
May 2026
Trainee: Emily Goering, PhD
Trainee: Jessie Axsom, RN, PhD
June 2026
Trainee: Doug Saforo, MD, PhD
Some Notable Papers- The Science Done by T32 Trainees
Biyik Sit, Rumeysa et al. 2025. Longitudinal single-cell multiomic atlas of high-risk neuroblastoma reveals chemotherapy-induced tumor microenvironment rewiring. Nat Genet. PMID: 40229600.
Blanchard, Tatiana et al. 2025. LOXHD1 is an oncofusion-regulated antigen of ewing sarcoma. Sci Rep, 15, 13007. PMID: 40234527.
Hamilton, Amber et al. 2024. A proteogenomic surfaceome study identifies DLK1 as an immunotherapeutic target in neuroblastoma. Cancer Cell, 42, 1970-1982.e7. PMID: 39454577.
Kahn, Benjamin et al. 2025. Intrinsic properties of the lymph node render it immunologically susceptible to metastasis. Cancer Discov. PMID: 40265527.
Matthew, Divij et al. 2024. Combined JAK inhibition and PD-1 immunotherapy for non-small cell lung cancer patients. Science, 384, eadf1329. PMID: 38900877.
Stone, Meredith et al. 2024. Hepatocytes coordinate immune evasion in cancer via release of serum amyloid A proteins. Nat Immunol, 25, 755-763. PMID: 38641718.
Tran, Khoa et al. 2024. SIRT7 regulates NUCKS1 chromatin binding to elicit metabolic and inflammatory gene expression in senescence and liver aging. bioRxiv. PMID: 38370824.
Kemp, Samantha et al. 2023. Efficacy of a Small-Molecule Inhibitor of KrasG12D in Immunocompetent Models of Pancreatic Cancer. Cancer Discov, 13, 298-311. PMID: 36472553.
Giles, Josephine et al. 2022. Shared and distinct biological circuits in effector, memory and exhausted CD8(+) T cells revealed by temporal single-cell transcriptomics and epigenetics. Nat Immunol, 23, 1600-1613. PMID: 36271148.
Kim, Gloria et al. 2022. Quantitative immunopeptidomics reveals a tumor stroma-specific target for T cell therapy. Sci Transl Med, 14, eabo6135. PMID: 36044599.
Lund, Peder et al. 2022. Stable isotope tracing in vivo reveals a metabolic bridge linking the microbiota to host histone acetylation. Cell Rep, 41, 111809. PMID: 36516747.
Perry, Joseph et al. 2022. PD-L1-PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection. Nat Immunol, 23, 743-756. PMID: 35437326.
1a9eGuadette, Brian et al. 2021. Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation. J Clin Invest, 131. PMID: 34473651.
Lanauze, Claudia et al. 2021. Colorectal Cancer-Associated Smad4 R361 Hotspot Mutations Boost Wnt/beta- Catenin Signaling through Enhanced Smad4-LEF1 Binding. Mol Cancer Res, 19, 823-833. PMID: 33608451.
Schwartz, Gregory et al. 2021. TooManyPeaks identifies drug-resistant-specific regulatory elements from single-cell leukemic epigenomes. Cell Rep, 36, 109575. PMID: 34433064.
Chirino, Leilani et al. 2020. TAM receptors attenuate murine NK-cell responses via E3 ubiquitin ligase Cbl-b. Eur J Immunol, 50, 48-55. PMID: 31531847.
Goldsmith, Jason et al. 2020. TNFAIP8 controls murine intestinal stem cell homeostasis and regeneration by regulating microbiome-induced Akt signaling. Nat Commun, 11, 2591. PMID: 32444641.
Payne, Kyle et al. 2020. BTN3A1 governs antitumor responses by coordinating alphabeta and gammadelta T cells. Science, 369, 942-949. PMID: 32820120.
Rome, Kelly et al. 2020. Trib1 regulates T cell differentiation during chronic infection by restraining the effector program. J Exp Med, 217. PMID: 32150623.
Roy, Nathan et al. 2020. LFA-1 signals to promote actin polymerization and upstream migration in T cells. J Cell Sci, 133. PMID: 32907931.
Walton, Zandra et al. 2018. Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR. Cell, 174, 72-87.e32. PMID: 29861175.
Hu, Biliang et al. 2017. Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18. Cell Rep, 20, 3025-3033. PMID: 28954221.
Layman, Awo Akosua Kesewa et al. 2017. Ndfip1 restricts mTORC1 signalling and glycolysis in regulatory T cells to prevent autoinflammatory disease. Nat Commun, 8, 15677. PMID: 28580955.
Chao, Timothy Hue-Fung, et al. 2016. CXCR2-Dependent Accumulation of Tumor-Associated Neutrophils Regulates T-cell Immunity in Pancreatic Ductal Adenocarcinoma. Cancer Immunol Res, 4, 968-982. PMID: 27737879.
Smith, Janessa et al. 2016. Tumor Regression and Delayed Onset Toxicity Following B7-H4 CAR T Cell Therapy. Mol Ther, 24, 1987-1999. PMID: 27439899.