E. John Wherry, PhD

Photo of E. John Wherry, PhDChair, Department of Systems Pharmacology and Translational Therapeutics
Richard and Barbara Schiffrin President's Distinguished Professor  
Director, Institute for Immunology

University of Pennsylvania 
354 BRB II/III , 421 Curie Boulevard 
Philadelphia, PA 19104-6160
Email Address 

For scheduling, administrative and departmental issues please contact 
Sam HalterEmail Address

For laboratory related questions, please contact
Maura McLaughlin JonesEmail Address

Lab in the News

  • Sorry, a Coronavirus Infection Might Not Be Enough to Protect You Thursday, September 16, 2021
  • As COVID-19 Booster Shots Near, Penn Immunologist Explains Why He Hates the Term ‘Breakthrough Infection’ Tuesday, August 31, 2021

    E. John Wherry, PhD, chair of Systems Pharmacology and Translational Therapeutics and director of the Penn Institute for Immunology, spoke with Philly Voice about growing research on the effectiveness of the mRNA COVID-19 vaccines and immune responses to those vaccines. Wherry’s team at Penn has closely examined the intricate details of the body’s immune response to a natural coronavirus infection and vaccination, accounting for multiple known variants. His lab studies not just the production of antibodies, but also the long-term blueprint for protection from memory B cells and T cells.

  • COVID-19 Vaccine Booster Shots: What You Need to Know Tuesday, August 31, 2021

    Though research is continuing, early data using different methodologies suggests that immunity from the vaccines wanes at about eight months or earlier as the coronavirus’ Delta variant spreads. E. John Wherry, PhD, chair of Systems Pharmacology and Translational Therapeutics and director of the Penn Institute for Immunology, explained the research behind recommendations for booster shots, booster shots for immunocompromised patients, and why attention should still focus on getting the unvaccinated vaccinated.

More News