Nduka M. Amankulor
Presidential Associate Professor in Neurosurgery
Chief, Neurosurgical Oncology, Hospital of the University of Pennsylvania
Director U. Penn Brain Tumor Center, University of Pennsylvania Department Abramson Cancer Center
Director, Brain Tumor Center, Hospital of the University of Pennsylvania
Diversity Search Advisor, Department of Neurosurgery, University of Pennsylvania
Department: Neurosurgery
Contact information
3400 Civic Center Blvd
PCAM 15th Floor South
Philadelphia, PA 19104
PCAM 15th Floor South
Philadelphia, PA 19104
Office: 215-662-3487
Fax: 215-349-5534
Fax: 215-349-5534
Education:
BA (Philosophy)
New York University, 1998.
MD (Medicine)
Yale School of Medicine, 2004.
BA (Philosophy)
New York University, 1998.
MD (Medicine)
Yale School of Medicine, 2004.
Post-Graduate Training
Intern, Department of Surgery, Yale New Haven Hospital, New Haven, CT, 2004-2005.
Resident, Department of Neurosurgery, Yale School of Medicine, New Haven, CT, 2005-2010.
Postdoctoral Research Fellow, Department of Cancer, Biology & Genetics, Department of Neurosurgery , Memorial Sloan-Kettering Cancer Center, New York, NY, 2007-2009.
Chief Resident, Department of Neurosurgery , Yale School of Medicine, New Haven, CT, 2010-2011.
Clinical Fellow, Department of Neurosurgical Oncology, Memorial Sloan- Kettering Cancer Center, New York, NY, 2011-2012.
Intern, Department of Surgery, Yale New Haven Hospital, New Haven, CT, 2004-2005.
Resident, Department of Neurosurgery, Yale School of Medicine, New Haven, CT, 2005-2010.
Postdoctoral Research Fellow, Department of Cancer, Biology & Genetics, Department of Neurosurgery , Memorial Sloan-Kettering Cancer Center, New York, NY, 2007-2009.
Chief Resident, Department of Neurosurgery , Yale School of Medicine, New Haven, CT, 2010-2011.
Clinical Fellow, Department of Neurosurgical Oncology, Memorial Sloan- Kettering Cancer Center, New York, NY, 2011-2012.
Certifications
American Board of Neurological Surgeons (ABNS) - Board Certified, 2017.
Permanent linkAmerican Board of Neurological Surgeons (ABNS) - Board Certified, 2017.
Selected Publications
Zhang D, Li AM, Hu G, Huang M, Yang F, Zhang L, Wellen KE, Xu X, Conn CS, Zou W, Kahn M, Rhoades SD, Weljie AM, Fuchs SY, Amankulor N, Yoshor D, Ye J, Koumenis C, Gong Y, Fan Y.: PHGDH-mediated endothelial metabolism drives glioblastoma resistance to chimeric antigen receptor TÂ cell immunotherapy. Cell Metab 35: 517-534, Mar 2023.Wilmott JS, Tawbi H, Engh JA, Amankulor NM, Shivalingam B, Banerjee H, Vergara IA, Lee H, Johansson PA, Ferguson PM, Saiag P, Robert C, Grob JJ, Butterfield LH, Scolyer RA, Kirkwood JM, Long GV, Davies MA.: Clinical Features Associated with Outcomes and Biomarker Analysis of Dabrafenib plus Trametinib Treatment in Patients with BRAF-Mutant Melanoma Brain Metastases. Clin Cancer Res 29: 521-531, Feb 2023.
Nabavizadeh A, Bagley SJ, Doot RK, Ware JB, Young AJ, Ghodasara S, Zhao C, Anderson H, Schubert E, Carpenter EL, Till J, Henderson F Jr, Pantel AR, Chen HI, Lee JYK, Amankulor NM, O'Rourke DM, Desai A, Nasrallah MP, Brem S.: Distinguishing Progression from Pseudoprogression in Glioblastoma Using (18)F-Fluciclovine PET. J Nucl Med Dec 2022.
Zhang X, Jaman E, Habib A, Ozpinar A, Andrews E, Amankulor NM, Zinn PO.: A Novel 5-Aminolevulinic Acid-Enabled Surgical Loupe System-A Consecutive Brain Tumor Series of 11 Cases. Oper Neurosurg (Hagerstown) 22: 298-304, May 2022.
Lee DM, Sun A, Patil SS, Liu L, Rao AV, Trent PT, Ali AA, Liu C, Rausch JL, Presutti LD, Kaczorowski A, Schneider F, Amankulor NM, Shuda M, Duensing A.: Targeting the translational machinery in gastrointestinal stromal tumors (GIST): a new therapeutic vulnerability. Sci Rep 12: 8275, May 2022.
Reed-Guy L, Desai AS, Phillips RE, Croteau D, Albright K, O'Neill M, Brem S, O'Rourke DM, Amankulor NM, Bagley SJ.: Risk of intracranial hemorrhage with direct oral anticoagulants versus low molecular weight heparin in glioblastoma: A retrospective cohort study. Neuro Oncol 24: 2172-2179, May 2022.
Howard SD, Kvint S, Borja AJ, Dimentberg R, Shultz K, Amankulor NM, McClintock SD, Malhotra NR.: Matched analysis of patient gender and meningioma resection outcomes. Br J Neurosurg Apr 2022.
Golbourn BJ, Halbert ME, Halligan K, Varadharajan S, Krug B, Mbah NE, Kabir N, Stanton AJ, Locke AL, Casillo SM, Zhao Y, Sanders LM, Cheney A, Mullett SJ, Chen A, Wassell M, Andren A, Perez J, Jane EP, Premkumar DRD, Koncar RF, Mirhadi S, McCarl LH, Chang YF, Wu YL, Gatesman TA, Cruz AF, Zapotocky M, Hu B, Kohanbash G, Wang X, Vartanian A, Moran MF, Lieberman F, Amankulor NM, Wendell SG, Vaske OM, Panigrahy A, Felker J, Bertrand KC, Kleinman CL, Rich JN, Friedlander RM, Broniscer A, Lyssiotis C, Jabado N, Pollack IF, Mack SC, Agnihotri S.: Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome. Nat Cancer Apr 2022.
Agarwal P, Beale OM, Zhang X, Sandlesh P, Jaman E, Amankulor N.: Machine Learning Identification of Immunotherapy Targets in Low-Grade Glioma Using RNA Sequencing Expression Data. World Neurosurg Apr 2022.
Beiriger J, Habib A, Jovanovich N, Kodavali CV, Edwards L, Amankulor N, Zinn PO.: The Subventricular Zone in Glioblastoma: Genesis, Maintenance, and Modeling. Front Oncol 12: 790976, Mar 2022.