Division of Hematology/Oncology


faculty photo

Selina M. Luger, M.D.

Professor of Medicine at the Hospital of the University of Pennsylvania
Attending Physician , Hospital of the University of Pennsylvania
Member , Abramson Cancer Center, University of Pennsylvania
Director, Outpatient Practice, Stem Cell Transplant & Hematological Malignancies, Hospital of the University of Pennsylvania
Director, Leukemia Program, Abramson Cancer Center, Perelman School of Medicine
Chair,Hematology-Oncology Epic Governance, Perelman School of Medicine, University of Pennsylvania
Member, Epic Operations Committee, Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Perelman Center 2 West
34th and Civic Center Blvd
Philadelphia, PA 19104
Office: 2156141847
Fax: 2156624064
A.B. (Biochemistry)
Harvard University, 1982.
M.D.CM (Medicine)
McGill University, 1987.
Post-Graduate Training
Intern, Internal Medicine , Presbyterian University Hospital, Pittsburgh, 1987-1988.
Resident, Internal Medicine , Presbyterian University Hospital, Pittsburgh, 1988-1990.
Fellowship, Hematology-Oncology , University of Pennsylvania, Philadelphia, 1990-1993.
Royal College of Physicians & Surgeons of Canada, 1990.
ABIM/Internal Medicine, 1990.
ABIM/Medical Oncology, 1993.
ABIM/Hematology, 2006.
Permanent link
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Description of Research Expertise

Leukemia, myelodysplastic syndrome, myeloproliferative disorders

Description of Clinical Expertise

hematologic malignancies, leukemia, AML, ALL, CML, myelodysplastic syndrome, MDS, myeloproliferative disorders, stem cell transplantation, bone marrow transplant

Selected Publications

Landsburg, Daniel J. Stadtmauer, Edward. Loren, Alison. Goldstein, Steven. Frey, Noelle. Nasta, Sunita D. Porter, David L. Tsai, Donald E. Perl, Alexander E. Hexner, Elizabeth O. Luger, Selina.: Receipt of maintenance therapy is most predictive of survival in older acute lymphoblastic leukemia patients treated with intensive induction chemotherapy regimens. American Journal of Hematology 88(8): 657-60, Aug 2013.

Kumar Anita J, Hexner Elizabeth O, Frey Noelle V, Luger Selina M, Loren Alison W, Reshef Ran, Boyer Jean, Smith Jacqueline, Stadtmauer Edward A, Levine Bruce L, June Carl H, Porter David L, Goldstein Steven C: Pilot study of prophylactic ex vivo costimulated donor leukocyte infusion after reduced-intensity conditioned allogeneic stem cell transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 19(7): 1094-101, Jul 2013.

DiNardo, Courtney D. Propert, Kathleen J. Loren, Alison W. Paietta, Elisabeth. Sun, Zhuoxin. Levine, Ross L. Straley, Kimberly S. Yen, Katharine. Patel, Jay P. Agresta, Samuel. Abdel-Wahab, Omar. Perl, Alexander E. Litzow, Mark R. Rowe, Jacob M. Lazarus, Hillard M. Fernandez, Hugo F. Margolis, David J. Tallman, Martin S. Luger, Selina M. Carroll, Martin.: Serum 2-hydroxyglutarate levels predict isocitrate dehydrogenase mutations and clinical outcome in acute myeloid leukemia. Blood 121(24): 4917-24, Jun 13 2013.

Gojo Ivana, Perl Alexander, Luger Selina, Baer Maria R, Norsworthy Kelly J, Bauer Kenneth S, Tidwell Michael, Fleckinger Stephanie, Carroll Martin, Sausville Edward A: Phase I study of UCN-01 and perifosine in patients with relapsed and refractory acute leukemias and high-risk myelodysplastic syndrome. Investigational new drugs 31(5): 1217-27, Feb 2013.

Dinardo Courtney D, Ogdie Alexis, Hexner Elizabeth O, Frey Noelle V, Loren Alison W, Luger Selina M: Characteristics and outcome of acute myeloid leukemia in patients with a prior history of autoimmune disease. Leukemia & lymphoma 54(6): 1235-41, Feb 2013.

Marks David I, Moorman Anthony V, Chilton Lucy, Paietta Elisabeth, Enshaie Amir, De Wald Gordon, Harrison Christine, Fielding Adele K, Foroni Letizia, Goldstone Anthony H, Litzow Mark R, Luger Selina M, McMillan Andrew K, Racevskis Janis, Rowe Jacob M, Tallman Martin S, Wiernik Peter, Lazarus Hillard M: The clinical characteristics, therapy and outcome of 85 adults with acute lymphoblastic leukemia and t(4;11)(q21;q23)/MLL-AFF1 prospectively treated on UKALLXII/ECOG2993. Haematologica 98(6): 945-52, Jan 2013.

Diab Adi, Zickl Lynette, Abdel-Wahab Omar, Jhanwar Suresh, Gulam Manjit A, Panageas Katherine S, Patel Jay P, Jurcic Joseph, Maslak Peter, Paietta Elisabeth, Mangan James K, Carroll Martin, Fernandez Hugo F, Teruya-Feldstein Julie, Luger Selina M, Douer Dan, Litzow Mark R, Lazarus Hillard M, Rowe Jacob M, Levine Ross L, Tallman Martin S: Acute myeloid leukemia with translocation t(8;16) presents with features which mimic acute promyelocytic leukemia and is associated with poor prognosis. Leukemia research 37(1): 32-6, Jan 2013.

Greenwald Daniel R, Li Hailun, Luger Selina M, Go Ronald S, King David, Patel Taral, Gascoyne Randy D, Kolesar Jill, Kahl Brad S, Horning Sandra: A phase II study of sorafenib (BAY 43-9006) in recurrent diffuse large B cell lymphoma: an eastern cooperative oncology group study (E1404). Journal of hematology & oncology 6: 46, 2013.

Geng Huimin, Brennan Sarah, Milne Thomas A, Chen Wei-Yi, Li Yushan, Hurtz Christian, Kweon Soo-Mi, Zickl Lynette, Shojaee Seyedmehdi, Neuberg Donna, Huang Chuanxin, Biswas Debabrata, Xin Yuan, Racevskis Janis, Ketterling Rhett P, Luger Selina M, Lazarus Hillard, Tallman Martin S, Rowe Jacob M, Litzow Mark R, Guzman Monica L, Allis C David, Roeder Robert G, Müschen Markus, Paietta Elisabeth, Elemento Olivier, Melnick Ari M: Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia. Cancer discovery 2(11): 1004-23, Nov 2012.

Kantarjian Hagop, Faderl Stefan, Garcia-Manero Guillermo, Luger Selina, Venugopal Parameswaran, Maness Lori, Wetzler Meir, Coutre Steven, Stock Wendy, Claxton David, Goldberg Stuart L, Arellano Martha, Strickland Stephen A, Seiter Karen, Schiller Gary, Jabbour Elias, Chiao Judy, Plunkett William: Oral sapacitabine for the treatment of acute myeloid leukaemia in elderly patients: a randomised phase 2 study. The lancet oncology 13(11): 1096-104, Nov 2012.

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Last updated: 12/04/2013
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