Selina M. Luger, M.D., FRCPC

faculty photo
Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Division of Hematology Oncology
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-157
34th and Civic Center Blvd
Philadelphia, PA 19104
Office: 215-614-1847
Fax: 215-615-5888
Education:
A.B. (Biochemistry)
Harvard University, 1982.
M.D.CM (Medicine)
McGill University, 1987.
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Description of Research Expertise

Leukemia, myelodysplastic syndrome, myeloproliferative disorders
MDS, AML, CML, ALL

Description of Clinical Expertise

hematologic malignancies, leukemia, AML, ALL, CML, myelodysplastic syndrome, MDS, myeloproliferative disorders, stem cell transplantation, bone marrow transplant

Selected Publications

McMahon CM; Ferng T; Canaani J; Wang ES; Morrissette JJD; Eastburn DJ; Pellegrino M; Durruthy-Durruthy R; Watt CD; Asthana S; Lasater EA; DeFilippis R; Peretz CAC; McGary LHF; Deihimi S; Logan AC; Luger SM; Shah NP; Carroll M; Smith CC; Perl AE.: Clonal Selection with RAS Pathway Activation Mediates Secondary Clinical Resistance to Selective FLT3 Inhibition in Acute Myeloid Leukemia. Cancer Discovery Aug 2020.

Foss, FM, Wang, XV, Luger, SM, Jegede, O, Miller, KB, Stadtmauer, EA, Whiteside, TL, Avigan, DE, Gascoyne, RD, Arber, D, Wagner, H, Strair, RK, Hogan, WJ, Sprague, KA, Lazarus, HM, Litzow, MR, Tallman, MS, Horning, SJ: Incorporation of extracorporeal photopheresis into a reduced intensity conditioning regimen in myelodysplastic syndrome and aggressive lymphoma: results from ECOG 1402 and 1902. Transfusion 60(8): 1867-1872, AUG 2020.

Zeidan, AM, Boddu, PC, Patnaik, MM, Bewersdorf, JP, Stahl, M, Rampal, RK, Shallis, RM, Steensma, DP, Savona, MR, Sekeres, MA, Roboz, GJ, DeAngelo, DJ, Schuh, AC, Padron, E, Zeidner, JF, Walter, RB, Onida, F, Fathi, AT, DeZern, A, Hobbs, G, Stein, EM, Vyas, P, Wei, AH, Bowen, DT, Montesinos, P, Griffiths, EA, Verma, AK, Keyzner, A, Bar-Natan, M, Navada, SC, Kremyanskaya, M, Goldberg, AD, Al-Kali, A, Heaney, ML, Nazha, A, Salman, H, Luger, S, Pratz, KW, Konig, H, Komrokji, R, Deininger, M, Cirici, BX, Bhatt, VR, Silverman, LR, Erba, HP, Fenaux, P, Platzbecker, U, Santini, V, Wang, ES, Tallman, MS, Stone, RM, Mascarenhas, J: Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts. Lancet Haematol. 7(8): E601-E612, AUG 2020.

Kim GYG; Burns J; Freyer CW; Hamilton KW; Frey NV; Gill SI; Hexner EO; Luger SM; Mangan JK; Martin ME; McCurdy SR; Perl AE; Porter DL; Schuster MG; Stadtmauer EA; Loren AW.: Risk of invasive fungal infections in patients with high-risk MDS and AML receiving hypomethylating agents. Am J Hematol 95: 792-798, July 2020.

Kim, GY, Burns, J, Freyer, CW, Hamilton, KW, Frey, NV, Gill, SI, Hexner, EO, Luger, SM, Mangan, JK, Martin, ME, McCurdy, SR, Perl, AE, Porter, DL, Schuster, MG, Stadtmauer, EA, Loren, AW: Risk of invasive fungal infections in patients with high-risk MDS and AML receiving hypomethylating agents. Am J Hematol 95(7): 792-798, JUL 2020.

Freyer, CW, Carulli, A, Ganetsky, A, Hughes, ME, Krause, TM, Timlin, C, Frey, NV, Gill, SI, Hexner, EO, Loren, AW, Mangan, JK, Martin, ME, McCurdy, SR, Perl, AE, Pratz, K, Porter, DL, Luger, SM: Venous thromboembolism following pegaspargase in adults receiving antithrombin supplementation. Leukemia & Lymphoma 61(9): 2200-2207, JUL 28 2020.

Pagel, JM, Othus, M, Garcia-Manero, G, Fang, M, Radich, JP, Rizzieri, DA, Marcucci, G, Strickland, SA, Litzow, MR, Savoie, ML, Spellman, SR, Confer, DL, Chell, JW, Brown, M, Medeiros, BC, Sekeres, MA, Lin, TL, Uy, GL, Powell, BL, Bayer, RL, Larson, RA, Stone, RM, Claxton, D, Essell, J, Luger, SM, Mohan, SR, Moseley, A, Erba, HP, Appelbaum, FR: Rapid Donor Identification Improves Survival in High-Risk First-Remission Patients With Acute Myeloid Leukemia. JCO Oncolocy Practice 16(6): 331-+ JUN 2020.

Pine, AB, Chokr, N, Stahl, M, Steensma, DP, Sekeres, MA, Litzow, MR, Luger, SM, Stone, RM, Greenberg, PL, Bejar, R, Bewersdorf, JP, Gore, SD, Zeidan, AM: Wide variation in use and interpretation of gene mutation profiling panels among health care providers of patients with myelodysplastic syndromes: results of a large web-based survey. Leukemia & Lymphoma 61(6): 1455-1464, MAY 11 2020.

Shallis, RM, Stahl, M, Wei, W, Montesinos, P, Lengline, E, Neukirchen, J, Bhatt, VR, Sekeres, MA, Fathi, AT, Konig, H, Luger, S, Khan, I, Roboz, GJ, Cluzeau, T, Martinez-Cuadron, D, Raffoux, E, Germing, U, Umakanthan, JM, Mukhereje, S, Brunner, AM, Miller, A, McMahon, CM, Ritchie, EK, Rodriguez-Veiga, R, Itzykson, R, Boluda, B, Rabian, F, Tormo, M, Cruz, EA, Rabinovich, E, Yoo, B, Cano, I, Podoltsev, NA, Bewersdorf, JP, Gore, S, Zeidan, AM: Patterns of care and clinical outcomes of patients with newly diagnosed acute myeloid leukemia presenting with hyperleukocytosis who do not receive intensive chemotherapy. Leukemia & Lymphoma 61(5): 1220-1225, APR 15 2020.

Frey NV; Shaw PA; Hexner EO; Pequignot E; Gill S; Luger SM; Mangan JK; Loren AW; Perl AE; Maude SL; Grupp SA; Shah NN; Gilmore J; Lacey SF; Melenhorst JJ; Levine BL; June CH; Porter DL.: Optimizing Chimeric Antigen Receptor T-Cell Therapy for Adults With Acute Lymphoblastic Leukemia. J Clin Oncol 38, Feb 2020.

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Last updated: 02/16/2021
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