Elizabeth Olson Hexner, MD, MSTR
Associate Professor of Medicine (Hematology-Oncology) at the Hospital of the University of Pennsylvania
Department: Medicine
Contact information
Division of Hematology Oncology
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-151
3400 Civic Center Boulevard
Philadelphia, PA 19104
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-151
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-614-1847
Fax: 215-615-5888
Fax: 215-615-5888
Links
Penn Center for Myeloproliferative Neoplasms
The Cell and Gene Therapy Toolkit for Junior Faculty
Penn Center for Myeloproliferative Neoplasms
The Cell and Gene Therapy Toolkit for Junior Faculty
Education:
A.B. (French/Comparative Area Studies)
Duke University, 1992.
(Premedical Studies)
Harvard University Extension School, 1994.
M.D. (Medicine)
Columbia College of Physicians and Surgeons, 1999.
M.S.T.R. (Translational Research)
University of Pennsylvania, 2009.
Permanent linkA.B. (French/Comparative Area Studies)
Duke University, 1992.
(Premedical Studies)
Harvard University Extension School, 1994.
M.D. (Medicine)
Columbia College of Physicians and Surgeons, 1999.
M.S.T.R. (Translational Research)
University of Pennsylvania, 2009.
Description of Research Expertise
Genetically modified T Cell TherapiesCAR T cells
Cellular therapy
Blood and Marrow Transplantation
Myeloproliferative Neoplasms
Umbilical Cord Blood Transplantation
Selected Publications
Wang X, Gimotty PA, Matthews AH, Mamtani R, Luger SM, Hexner EO, Babushok DV, McCurdy SR, Frey NV, Bruno XJ, Gill S, Martin ME, Paralkar VR, Maillard I, Porter DL, Loren AW, Perl AE, Pratz KW, Getz KD, Lai C.: Evolving racial/ethnic disparities in AML survival in the novel therapy era. Blood Adv Feb 2025.Shannon R. McCurdy, Anthony D Sung, Rebecca T. Brown, Marni Kessler, Nelson J. Chao, Thuy T. Koll, Alfred Fisher, Ernaya Johnson, Meagan Lew, Lauren Bohannon, Sanghee Hong, Pashna Munshi, Saar I. Gill, Nasheed M. Hossain, Sarah Skuli, Noelle V. Frey, Elizabeth O Hexner, Ximena Jordan Bruno, Daria Babushock, Catherine E. Lai, Mary Ellen Martin, Selina M. Luger, David L Porter, Alison W. Loren, Vijaya Raj Bhatt, Phyllis Gimotty: Machine Learning Models Demonstrate Gait Speed As the Best Predictor of Survival and Relapse-Free Survival in Older Adults Undergoing Allogeneic Hematopoietic Cell Transplantation. Transplantation and Cellular Therapy Feb 2025.
Alison Carulli, Brendan L. Mangan, Rachel Hartman, Mrs. Lindsey MacDonald, Mr. Christopher J. Catania, Noelle V. Frey, Saar Gill, Elizabeth O Hexner, Mary Ellen Martin, Nasheed M. Hossain, Alison W. Loren, Selina M. Luger, Shannon R. McCurdy, David L Porter, Keith W. Pratz, Jacqueline Smith, Pashna Munshi: Early Mixed Chimerism and Relapse Rates for Acute Myeloid Leukemia/Myelodysplastic Syndrome after Allogeneic Hematopoietic Stem Cell Transplantation. Transplantation and Cellular Therapy Feb 2025.
Ashley D. Hadjis, Honghong Sun, Yangzhu Du, Rebecca T. Brown, Pashna Munshi, Saar I. Gill, Nasheed M. Hossain, Sarah Skuli, Noelle V. Frey, Elizabeth O Hexner, Ximena Jordan Bruno, Catherine E. Lai, Mary Ellen Martin, Selina M. Luger, David L Porter, Alison W. Loren, Shannon R. McCurdy: Graft-Versus-Host Disease (GVHD) and Senescence-Associated Biomarkers Correlate with Frailty and Survival in Older Adults Undergoing Hematopoietic Cell Transplantation (HCT) Transplantation and Cellular Therapy Feb 2025.
Nasheed M. Hossain, Mr. Christopher J. Catania, Stefan K. Barta, Noelle V. Frey, Saar I. Gill, Elizabeth O Hexner, Mary Ellen Martin, Shannon R. McCurdy, Pashna Munshi, Jacqueline Smith, Vikram R Paralkar, Ellen Kim, Alain Rook, Alison W. Loren, David L Porter: Leveraging Radiation and Graft Versus Lymphoma Effect for the Management of Relapsed/Refractory Cutaneous T-Cell Lymphoma. Transplantation and Cellular Therapy Feb 2025.
Jadlowsky JK, Hexner EO, Marshall A, Grupp SA, Frey NV, Riley JL, Veloso E, McConville H, Rogal W, Czuczman C, Hwang WT, Li Y, Leskowitz RM, Farrelly O, Karar J, Christensen S, Barber-Rotenberg J, Gaymon A, Aronson N, Bernstein W, Melenhorst JJ, Roche AM, Everett JK, Zolnoski SA, McFarland AG, Reddy S, Petrichenko A, Cook EJ, Lee C, Gonzalez VE, Alexander K, Kulikovskaya I, Ramírez-Fernández Á, Minehart JC, Ruella M, Gill SI, Schuster SJ, Cohen AD, Garfall AL, Shah PD, Porter DL, Maude SL, Levine BL, Siegel DL, Chew A, McKenna S, Lledo L, Davis MM, Plesa G, Herbst F, Stadtmauer EA, Tebas P, DiNofia A, Haas A, Haas NB, Myers R, O'Rourke DM, Svoboda J, Tanyi JL, Aplenc R, Jacobson JM, Ko AH, Cohen RB, June CH, Bushman FD, Fraietta JA: Long-term safety of lentiviral or gammaretroviral gene-modified T cell therapies. Nat Med Jan 2025 Notes: Co-1st Author.
Rowe, M., Babushok, D., Carroll, M., Carulli, A., Frey, N., Gill, S., Hexner, E., Hirsh, R., Hossain, N., Lai, C., Loren, A., Luger, S., Maillard, I., McCurdy, S., Matthews, A., Martin, M.E., Paralkar, V.R., Perl, A., Porter, D., Pratz, K., Stadtmauer, E. and Bruno, X.J. : Tumor Lysis Syndrome in Acute Myeloid Leukemia Patients Treated With a Venetoclax Based Regimen. Eur J Haematol 2025.
Ying WANG, Alicia Huaze Li, Ruqayyah sanders-Braggs, Yan Zhou, Mimi Chen, Tien Bui, Hongfa Zhu, Nasheed Hossain, Jonathan Soboloff, John Elrod, Elizabeth O. Hexner, Yi Zhang: Enforced Expression of Mitochondrial Calcium Uniporter in Donor T Cells Abolishes Gvhd Progression Blood Dec 2024.
Yu Akahoshi, Yoshihiro Inamoto, Nikolaos Spyrou, Hideki Nakasone, Francis A. Ayuk, Hannah Choe, Noriko Doki, Tetsuya Eto, Aaron Etra, Elizabeth O. Hexner, Nobuhiro Hiramoto, William J. Hogan, Ernst Holler, Keisuke Kataoka, Masatsugu Tanaka, Takashi Tanaka, Naoyuki Uchida, Ingrid Vasova, Fumihiko Ishimaru, Takahiro Fukuda, Yi-Bin Chen, Junya Kanda, Ryotaro Nakamura, Yoshiko Atsuta, James L.M. Ferrara, Yoshinobu Kanda, John Levine, Takanori Teshima: Refinement of Day 28 Treatment Response Criteria for Acute GVHD: A Collaboration Study of the JSTCT and MAGIC. Blood Dec 2024.
Nikolaos Katsivelos, Nikolaos Spyrou, Daniela Weber, Ingrid Vasova, Francis A. Ayuk, Hannah Choe, William J. Hogan, Zachariah Defilipp, Muna Qayed, Aaron Etra, Karamjeet S Sandhu, Sabrina Kraus, Timothy S. Olson, Elizabeth O. Hexner, Paibel Aguayo-Hiraldo, Ran Reshef, Evelyn Ullrich, Tal Schechter-Finkelstein, Carrie L. Kitko, Chantiya Chanswangphuwana, Pietro Merli, Yu Akahoshi, Janna Baez, Gilbert Eng, Rahnuma Beheshti, Steven Kowalyk, George Morales, Ioannis Evangelos Louloudis, Rachel Young, Ernst Holler, Ryotaro Nakamura, James L.M. Ferrara, John Levine: Serial Clinical and Biomarker Monitoring during Treatment Can Stratify Patients with Low Risk Gvhd. Blood Dec 2024.