Elizabeth Olson Hexner, M.D., M.S.T.R.
Assistant Professor of Medicine at the Hospital of the University of Pennsylvania
Attending Physician, Hospital of the University of Pennsylvania - Rhoads 7 Liquid Tumor Service
Department: Medicine
Contact information
Perelman Center for Advanced Medicine
2 West Pavilion
3400 Civic Center Boulevard
Philadelphia, PA 19104
2 West Pavilion
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215.614.1847
Fax: (215) 615-5888
Fax: (215) 615-5888
Education:
A.B. (French/Comparative Area Studies)
Duke University, 1992.
(Premedical Studies)
Harvard University Extension School, 1994.
M.D. (Medicine)
Columbia College of Physicians and Surgeons, 1999.
M.S.T.R. (Translational Research)
University of Pennsylvania, 2009.
A.B. (French/Comparative Area Studies)
Duke University, 1992.
(Premedical Studies)
Harvard University Extension School, 1994.
M.D. (Medicine)
Columbia College of Physicians and Surgeons, 1999.
M.S.T.R. (Translational Research)
University of Pennsylvania, 2009.
Post-Graduate Training
Intern, Department of Medicine, Columbia Presbyterian Hospital, 1999-2000.
Resident, Department of Medicine, Columbia Presbyterian Hospital, 2000-2002.
Fellow, Hematology/Oncology, University of Pennsylvania, 2002-2005.
Intern, Department of Medicine, Columbia Presbyterian Hospital, 1999-2000.
Resident, Department of Medicine, Columbia Presbyterian Hospital, 2000-2002.
Fellow, Hematology/Oncology, University of Pennsylvania, 2002-2005.
Certifications
American Board of Internal Medicine (Internal Medicine), 2002.
American Board of Internal Medicine (Medical Oncology), 2005.
American Board of Internal Medicine (Hematology), 2005.
Permanent linkAmerican Board of Internal Medicine (Internal Medicine), 2002.
American Board of Internal Medicine (Medical Oncology), 2005.
American Board of Internal Medicine (Hematology), 2005.
Description of Research Expertise
Myeloproliferative DisordersUmbilical Cord Blood Transplantation
Description of Clinical Expertise
Myeloproliferative NeoplasmsMyelodysplastic Syndromes
Acute leukemia
Selected Publications
Kalota, A., Jeschke, G. R., Carroll, M., Hexner, E. O.: Intrinsic resistance to JAK2 inhibition in myelofibrosis. Clin Cancer Res 2013.Lin, X., Rice, K. L., Buzzai, M., Hexner, E., Costa, F. F., Kilpivaara, O., Mullally, A., Soares, M. B., Ebert, B. L., Levine, R., Licht, J. D.: miR-433 is aberrantly expressed in myeloproliferative neoplasms and suppresses hematopoietic cell growth and differentiation. Leukemia 27: 344 - 52, 2013.
Verstovsek, S., Mesa, R. A. Gotlib, J., Levy, R. S., Gupta, V., DiPersio, J. F., Catalano, J. V., Deininger, M., Miller, C., Silver, R. T., Talpaz, M., Winton, E. F., Harvey, J. H., Jr., Arcasoy, M. O., Hexner, E., Lyons, R. M., Paquette, R., Raza, A., Vaddi, K., Erickson-Viitanen, S., Koumenis, I. L., Sun, W., Sandor, V., Kantarjian, H. M.: A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis. N Engl J Med 366(9): 799-807, March 2012.
Huang, J., Nguyen-McCarty, M., Hexner, E. O., Danet-Desnoyers, G., Klein, P. S.: Maintenance of hematopoietic stem cells through regulation of Wnt and mTOR pathways. Nature Medicine 18: 1778-85, 2012.
Reshef, R., Luger, S. M., Hexner, E. O., Loren, A. W., Frey, N. V., Nasta, S. D., Goldstein, S. C., Stadtmauer, E. A., Smith, J., Bailey, S., et al. : Blockade of lymphocyte chemotaxis in visceral graft-versus-host disease. N Engl J Med 367: 135-45, 2012.
Hubbeling, H, Frank D, Hexner, E: Myelofibrosis 2012: it’s complicated. Therapeutic Advances in Hematology 2012.
Wertheim, G. B., Hexner, E., Bagg, A.: Molecular-based classification of acute myeloid leukemia and its role in directing rational therapy : personalized medicine for profoundly promiscuous proliferations. Molecular diagnosis & therapy 2012.
Mascarenhas, J., Heaney, M. L., Najfeld, V., Hexner, E., Abdel-Wahab, O., Rampal, R., Ravandi, F., Petersen, B., Roboz, G., Feldman, E., Podoltsev, N., Douer, D., Levine, R., Tallman, M. and Hoffman, R. : Proposed criteria for response assessment in patients treated in clinical trials for myeloproliferative neoplasms in blast phase (MPN-BP): Formal recommendations from the post-myeloproliferative neoplasm acute myeloid leukemia consortium. Leukemia research 36: 1500-1504, 2012.
Tizon, R., Frey, N., Heitjan, D. F., Tan, K. S., Goldstein, S. C., Hexner, E. O., Loren, A., Luger, S. M., Reshef, R., Tsai, D., et al. : High-dose corticosteroids with or without etanercept for the treatment of idiopathic pneumonia syndrome after allo-SCT. Bone marrow transplantation. Bone marrow Transplantation 2012.
Dinardo, C. D., Ogdie, A., Hexner, E. O., Frey, N. V., Loren, A. W., Luger, S. M.: Characteristics and outcome of acute myeloid leukemia in patients with a prior history of autoimmune disease. Leuk Lymphoma 2012.
