Elizabeth Olson Hexner, MD, MSTR

faculty photo
Associate Professor of Medicine at the Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Division of Hematology Oncology
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-151
3400 Civic Center Boulevard
Philadelphia, PA 19104
Office: 215-614-1847
Fax: 215-615-5888
Education:
A.B. (French/Comparative Area Studies)
Duke University, 1992.
(Premedical Studies)
Harvard University Extension School, 1994.
M.D. (Medicine)
Columbia College of Physicians and Surgeons, 1999.
M.S.T.R. (Translational Research)
University of Pennsylvania, 2009.
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Description of Research Expertise

Genetically modified T Cell Therapies
CAR T cells
Cellular therapy
Blood and Marrow Transplantation
Myeloproliferative Neoplasms
Umbilical Cord Blood Transplantation

Selected Publications

Tian Y, Meng L, Wang y, Li B, Yu H, Zhou Y, Bui T, Abraham C, Li A, Zhang Y, Wang J, Zhao C, Mineishi S, Gallucci S, Porter DL, Hexner E, Zheng H, Zhang Y, Hu SS, and Zhang Y. : Graft-versus-host disease depletes plasmacytoid dendritic cell progenitors to impair tolerance induction. J Clin Invest 131(1), 2021.

Mascarenhas, John O, Rampal, Raajit K, Kosiorek, Heidi E, Bhave, Rupali, Hexner, Elizabeth, Wang, Eunice S, Gerds, Aaron, Abboud, Camille N, Kremyanskaya, Marina, Berenzon, Dimitry, Odenike, Olatoyosi, Farnoud, Noushin, Krishnan, Aishwarya, Weinberg, Rona Singer, McGovern, Erin, Salama, Mohamed E, Najfeld, Vesna, Medina-Martinez, Juan S, Arango Ossa, Juan E, Levine, Max F, Zhou, Yangyu, Sandy, Lonette, Heaney, Mark L, Levine, Ross L, Mesa, Ruben A, Dueck, Amylou C, Hoffman, Ronald: Phase 2 study of ruxolitinib and decitabine in patients with myeloproliferative neoplasm in accelerated and blast phase. Blood advances 4(20): 5246-5256, 2020.

Stadtmauer EA, Fraietta JA, Davis MM, Cohen AD, Weber KL, Lancaster E, Mangan PA, Kulikovskaya I, Gupta M, Chen F, Tian L, Gonzalez VE, Xu J, Jung IY, Melenhorst JJ, Plesa G, Shea J, Matlawski T, Cervini A, Gaymon AL, Desjardins S, Lamontagne A, Salas-Mckee J, Fesnak A, Siegel DL, Levine BL, Jadlowsky JK, Young RM, Chew A, Hwang WT, Hexner EO, Carreno BM, Nobles CL, Bushman FD, Parker KR, Qi Y, Satpathy AT, Chang HY, Zhao Y, Lacey SF, June CH.: CRISPR-engineered T cells in patients with refractory cancer. Science 2020.

Aziz MD, Shah J, Kapoor U, Dimopoulos C, Anand S, Augustine A, Ayuk F, Chaudhry M, Chen YB, Choe HK, Etra A, Gergoudis S, Hartwell MJ, Hexner EO, Hogan WJ, Kitko CL, Kowalyk S, Kröger N, Merli P, Morales G, Nakamura R, Ordemann R, Pulsipher MA, Qayed M, Reshef R, Rösler W, Schechter T, Schreiner E, Srinagesh H, Wölfl M, Wudhikarn K, Yanik G, Young R, Özbek U, Ferrara JLM, Levine JE.: Disease risk and GVHD biomarkers can stratify patients for risk of relapse and nonrelapse mortality post hematopoietic cell transplant. Leukemia 2020.

Frey, Noelle V, Shaw, Pamela A, Hexner, Elizabeth O, Pequignot, Edward, Gill, Saar, Luger, Selina M, Mangan, James K, Loren, Alison W, Perl, Alexander E, Maude, Shannon L, Grupp, Stephan A, Shah, Nirav N, Gilmore, Joan, Lacey, Simon F, Melenhorst, Jos J, Levine, Bruce L, June, Carl H, Porter, David L: Optimizing Chimeric Antigen Receptor T-Cell Therapy for Adults With Acute Lymphoblastic Leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 38(5): 415-422, 2020.

Aziz, Mina D, Shah, Jay, Kapoor, Urvi, Dimopoulos, Christina, Anand, Sarah, Augustine, Allan, Ayuk, Francis, Chaudhry, Mohammed, Chen, Yi-Bin, Choe, Hannah K, Etra, Aaron, Gergoudis, Stephanie, Hartwell, Matthew J, Hexner, Elizabeth O, Hogan, William J, Kitko, Carrie L, Kowalyk, Steven, Kröger, Nicolaus, Merli, Pietro, Morales, George, Nakamura, Ryotaro, Ordemann, Rainer, Pulsipher, Michael A, Qayed, Muna, Reshef, Ran, Rösler, Wolf, Schechter, Tal, Schreiner, Elisabeth, Srinagesh, Hrishikesh, Wölfl, Matthias, Wudhikarn, Kitsada, Yanik, Gregory, Young, Rachel, Özbek, Umut, Ferrara, James L M, Levine, John E: Disease risk and GVHD biomarkers can stratify patients for risk of relapse and nonrelapse mortality post hematopoietic cell transplant. Leukemia 34(7): 1898-1906, 2020.

Freyer, Craig W, Carulli, Alison, Ganetsky, Alex, Hughes, Mitchell E, Krause, Tracy M, Timlin, Colleen, Frey, Noelle V, Gill, Saar I, Hexner, Elizabeth O, Loren, Alison W, Mangan, James K, Martin, Mary Ellen, McCurdy, Shannon R, Perl, Alexander E, Pratz, Keith, Porter, David L, Luger, Selina M: Venous thromboembolism following pegaspargase in adults receiving antithrombin supplementation. Leukemia & lymphoma 61(9): 2200-2207, 2020.

Gerds, Aaron T, Gotlib, Jason, Bose, Prithviraj, Deininger, Michael W, Dunbar, Andrew, Elshoury, Amro, George, Tracy I, Gojo, Ivana, Gundabolu, Krishna, Hexner, Elizabeth, Hobbs, Gabriela, Jain, Tania, Jamieson, Catriona, Kuykendall, Andrew T, McMahon, Brandon, Mohan, Sanjay R, Oehler, Vivian, Oh, Stephen, Pardanani, Animesh, Podoltsev, Nikolai, Ranheim, Erik, Rein, Lindsay, Salit, Rachel, Snyder, David S, Stein, Brady L, Talpaz, Moshe, Thota, Swapna, Vachhani, Pankit, Wadleigh, Martha, Walsh, Katherine, Ward, Dawn C, Bergman, Mary Anne, Sundar, Hema: Myeloid/Lymphoid Neoplasms with Eosinophilia and TK Fusion Genes, Version 3.2021, NCCN Clinical Practice Guidelines in Oncology. Journal of the National Comprehensive Cancer Network : JNCCN 18(9): 1248-1269, 2020.

Frey, Noelle V, Gill, Saar, Hexner, Elizabeth O, Schuster, Stephen, Nasta, Sunita, Loren, Alison, Svoboda, Jakub, Stadtmauer, Edward, Landsburg, Daniel J, Mato, Anthony, Levine, Bruce L, Lacey, Simon F, Melenhorst, Jan Joseph, Veloso, Elizabeth, Gaymon, Avery, Pequignot, Edward, Shan, Xinhe, Hwang, Wei-Ting, June, Carl H, Porter, David L: Long-Term Outcomes From a Randomized Dose Optimization Study of Chimeric Antigen Receptor Modified T Cells in Relapsed Chronic Lymphocytic Leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 38(25): 2862-2871, 2020.

Tian, Yuanyuan, Meng, Lijun, Wang, Ying, Li, Bohan, Yu, Hongshuang, Zhou, Yan, Bui, Tien, Li, Alicia, Abraham, Ciril, Zhang, Yongping, Wang, Jian, Zhao, Chenchen, Mineishi, Shin, Gallucci, Stefania, Porter, David, Hexner, Elizabeth, Zheng, Hong, Zhang, Yanyun, Hu, Shaoyan, Zhang, Yi: Graft-versus-host disease depletes plasmacytoid dendritic cell progenitors to impair tolerance induction. The Journal of clinical investigation 2020.

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Last updated: 05/12/2021
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