faculty photo

Anne Rentoumis Cappola

Associate Professor of Medicine
Department: Medicine
Graduate Group Affiliations

Contact information
Division of Endocrinology, Diabetes, and Metabolism
Room 12-136
Smilow Center for Translational Research, 12th floor
3400 Civic Center Blvd., Building 421
Philadelphia, PA 19104-5160
Office: (215) 573-5359
Fax: (215) 898-5408
Education:
B.A. (Biochemistry )
Harvard College (Advanced Standing), Cambridge, MA, 1990.
M.D.
University of Pennsylvania School of Medicine, 1994.
Sc.M. (Clinical Epidemiology)
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2001.
Post-Graduate Training
Intern and Resident, Internal Medicine, Brigham and Women's Hospital, Boston, MA, 1994-1997.
Clinical Fellow, Endocrinology, Massachusetts General Hospital, Boston, MA, 1997-1998.
Clinical and Research Fellow, Endocrinology and Metabolism, Johns Hopkins Hospital, Baltimore, MD, 1998-2000.
Research Fellow, Center on Aging and Health, Johns Hopkins Medical Institutions, Baltimore, MD, 1999-2001.
Senior Honorary Visiting Fellow, University of Cambridge, Cambridge, UK, 2013-2014.
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Description of Research Expertise

Anne Rentoumis Cappola, M.D., Sc.M. is an Associate Professor of Medicine in the Division of Endocrinology, Diabetes, and Metabolism, Associate Scholar in the Center for Clinical Epidemiology (CCEB), Core Faculty Member of the Master's in Translational Research program, and a Fellow in the Institute on Aging. She is an Associate Editor for the Journal of the American Medical Association (JAMA).

Dr. Cappola's research focuses on the hormonal alterations that occur with aging and the clinical impact of these changes. She is funded by the National Institute on Aging. Current projects include studies of the indications for treatment of subclinical thyroid dysfunction in older men and women; the role of androgens in the health of older women; hormonal treatments for the frailty syndrome; and metabolic changes in men and women who sustain a hip fracture.

Selected Publications

Shores MM, Arnold AM, Biggs ML, Longstregth WT, Smith NL, Kizer JR, Cappola AR, Hirsch CH, Marck BT, Matsumoto AM: Testosterone and dihydrotestosterone and incident ischemic stroke in men in the Cardiovascular Health Study. Clin Endocrinol 81(5): 746-53, Nov 2014.

Collet TH, Bauer DC, Cappola AR, Åsvold BO, Weiler S, Vittinghoff E, Gussekloo J, Bremner A, den Elzen WP, Maciel RMB, Vanderpump MP, Cornuz J, Dörr M, Wallaschofski H, Newman AB, Sgarbi JA, Razvi S, Völzke H, Walsh JP, Aujesky D, Rodondi N, for the Thyroid Studies Collaboration: Thyroid antibody status, subclinical hypothyroidism and the risk of coronary heart disease - An individual participant data analysis. J Clin Endocrinol Metab 99(9): 3353-62, Sep 2014.

Garin MC, Arnold AM, Lee JS, Robbins J, Cappola AR: Subclinical thyroid dysfunction and hip fracture and bone mineral density in older adults: the Cardiovascular Health Study. J Clin Endocrinol Metab 99(8): 2657-64, Aug 2014.

Chen CT, Liu CT, Chen GK, Andrews JS, Arnold AM, Dreyfus J, Franceschini N, Garcia ME, Kerr KF, Li G, Lohman KK, Musani SK, Nalls MA, Raffel LJ, Smith J, Ambrosone CB, Bandera EV, Bernstein L, Britton A, Brzyski RG, Cappola A, Carlson CS, Couper D, Deming SL, Goodarzi MO, Heiss G, John EM, Lu X, Le Marchand L, Marciante K, McKnight B, Millikan R, Nock NL, Olshan AF, Press MF, Vaiyda D, Woods NF, Taylor HA, Zhao W, Zheng W, Evans MK, Harris TB, Henderson BE, Kardia SL, Kooperberg C, Liu Y, Mosley TH, Psaty B, Wellons M, Windham BG, Zonderman AB, Cupples LA, Demerath EW, Haiman C, Murabito JM, Rajkovic A: Meta-analysis of loci associated with age at natural menopause in African-American women. Hum Mol Genet 23(12): 3327-42, Jun 2014.

Shores MM, Biggs ML, Arnold AM, Smith NL, Longstreth WT, Kizer JR, Hirsch CH, Cappola AR, Matsumoto AM: Testosterone, dihydrotestosterone and incident cardiovascular disease and mortality in the Cardiovascular Health Study. J Clin Endocrinol Metab 99(6): 2061-68, Jun 2014.

Mariani LH, White MT, Shults J, Anderson CA, Feldman HI, Wolf M, Reese PP, Denburg MR, Townsend RR, Lo JC, Cappola AR, Carlow D, Gadegbeku CA, Steigerwalt S, Leonard MB; CRIC Study Investigators: Increasing use of vitamin D supplementation in the Chronic Renal Insufficiency Cohort Study. J Ren Nutr 24(3): 186-93, May 2014.

González-Fernández M, Humbert I, Winegrad H, Cappola AR, Fried LP: Dysphagia in old-old women: prevalence as determined according to self-report and the 3-ounce water swallowing test. J Amer Geriatr Soc 62(4): 716-20, Apr 2014.

Garin MC, Arnold AM, Lee JS, Tracy RP, Cappola AR: Subclinical hypothyroidism, weight change, and body composition in the elderly: the Cardiovascular Health Study J Clin Endocrinol Metab 99(4): 1220-6, Apr 2014.

Sanders JL, Ding V, Arnold AM, Kaplan RC, Cappola AR, Kizer JR, Boudreau RM, Cushman M, Newman AB: Do changes in circulating biomarkers track with each other and with functional changes in older adults? J Gerontology Med Sci 69(2): 174-81, Feb 2014.

Medici M, Porcu E, Pistis G, Teumer A, Brown SJ, Jensen RA, Rawal R, Roef GL, Plantinga TS, Vermeulen SH, Lahti J, Simmonds MJ, Husemoen LL, Freathy RM, Shields BM, Pietzner D, Nagy R, Broer L, Chakcer L, Korevaar TI, Plia MG, Sala C, Volker U, Richards JB, Sweep FC, Gieger C, Corre T, Kajantie E, Thuesen B, Taes YE, Visser WE, Hattersley AT, Kratzsch J, Hamilton A, Li W, Homuth G, Lobina M, Mariotti S, Soranzo N, Cocca M, Nauck M, Spielhagen C, Ross A, Arnold A, van de Bunt M, Liyanarachichi S, Heier M, Grabe JH, Masciullo C, Galesloot TE, Lim EM, Reischl E, Leedman PJ, Lai S, Delitala A, Bremner AP, Philips DI, Beilby JP, Mulas A, Vocale M, Abecasis G, Forsen T, James A, Widen E, Hui J, Prokisch H, Reitzschel EE, Palotie A, Feddema P, Fletcher SJ, Schramm K, Rotter JI, Kluttig A, Radke D, Traglia M, Surdulescu GL, He H, Franklyn JA, TIller D, Vaidya B, de Meyer T, Jorgensen T, Eriksson JG, O'Leary PC, Wichmann E, Hermus AR, Psaty BM, Itermann T, Hofman A, Bosi E, Schlessinger D, Wallaschofski H, Pirastu N, Aulchenko YS, de la Chapelle A, Netea-Maier RT, Gough SC, Meyer ZU, Schwabedissen H, Frayling TM, Kaufman JM, Linneberg A, Raikkonen K, Smit JW, Kiemeney LA, Rivadeneira F, Uitterlinden AG, Walksh JP, Meisinger C, den Heijer M, Visser TJ, Spector TD, Wilson SG, Volzke H, Cappola A, Toniolo D, Sanna S, Naitza S, Peeters RP: Identification of novel genetic loci associated with thyroid peroxidase antibodies and clinical thyroid disease PLOS Genetics 10(2): e1004123, Feb 2014.

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Last updated: 11/13/2014
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