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Anne Rentoumis Cappola

Professor of Medicine
Department: Medicine

Contact information
Division of Endocrinology, Diabetes, and Metabolism
Room 12-136
Smilow Center for Translational Research, 12th floor
3400 Civic Center Blvd., Building 421
Philadelphia, PA 19104-5160
Office: (215) 573-5359
Fax: (215) 898-5408
B.A. (Biochemistry )
Harvard College (Advanced Standing), Cambridge, MA, 1990.
University of Pennsylvania School of Medicine, 1994.
Sc.M. (Clinical Epidemiology)
Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2001.
Post-Graduate Training
Intern and Resident, Internal Medicine, Brigham and Women's Hospital, Boston, MA, 1994-1997.
Clinical Fellow, Endocrinology, Massachusetts General Hospital, Boston, MA, 1997-1998.
Clinical and Research Fellow, Endocrinology and Metabolism, Johns Hopkins Hospital, Baltimore, MD, 1998-2000.
Research Fellow, Center on Aging and Health, Johns Hopkins Medical Institutions, Baltimore, MD, 1999-2001.
Senior Honorary Visiting Fellow, University of Cambridge, Cambridge, UK, 2013-2014.
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Description of Research Expertise

Anne Rentoumis Cappola, M.D., Sc.M. is a Professor of Medicine in the Division of Endocrinology, Diabetes, and Metabolism; Director of the Clinical and Translational Research Center; and Director of Clinical Research for the Department of Medicine. She is an Associate Editor for the Journal of the American Medical Association (JAMA).

Dr. Cappola's research focuses on the hormonal alterations that occur with aging and the clinical impact of these changes. She is funded by the National Institute on Aging. Current projects include studies of the indications for treatment of subclinical thyroid dysfunction in older men and women; the role of androgens in the health of older women; hormonal treatments for the frailty syndrome; and metabolic changes in men and women who sustain a hip fracture.

Selected Publications

Maggio M, de Vita F, Lauretani F, Bandinelli S, Semba RD, Bartali B, Cherubini A, Cappola AR, Ceda GP, Ferrucci L: Relationship between carotenoids, retinol, and estradiol levels in older women. Nutrients 7(8): 6506-19, Aug 2015.

Åsvold BO, Vatten LJ, Bjøro T, Bauer DC, Bremner A, Cappola AR, Ceresini G, den Elzen WPJ, Ferrucci L, Franco OH, Franklyn JA, Gussekloo J, Iervasi G Imaizumi M, Kearney PM, Khaw KT, Newman AB, Peeters RP, Psaty BM, Razvi S, Sgarbi JA, Stott DK, Trompet S, Vanderpump MP, Völzke H, Walsh JP, Westendorp RG, Rodondi N, for the Thyroid Studies Collaboration: Thyroid function within the normal range and risk of coronary heart disease. JAMA-Internal Medicine 175(6): 1037-47, Jun 2015.

Chaker L, Baumgartner C, den Elzen W, Ikram, MA, Blum MR, Collet TH, Bakker SJ, Dehgha A, Drechsler C, Luben RN, Hofman A, Portegies ML, Medici M, Iervasi G, Stott DJ, Ford I, Bremner A, Wanner C, Ferrucci L, Newman A, Dullaart RP, Sgarbi JA, Ceresini G, Maciel RM, Westendorp R, Jukema JW, Imaizumi M, Franklyn JA, Bauer DC, Walsh JP, Rasvi S, Khaw KT, Cappola AR, Völzke H, Franco OH, Gussekloo J, Rodondi N, Peeters RP: Subclinical hypothyroidism and the risk of stroke events and fatal stroke: an individual participant data analysis. J Clin Endocrinol Metab 100(6): 2181-91, Jun 2015.

Blum MR, Bauer DC, Collet TH, Fink HA, Cappola AR, da Costa BR, Wirth CD, Peeters RP, Åsvold BO, den Elzen WP, Luben RN, Imaizumi M, Bremner AP, Gogakos A, Eastell R, Kearney PM, Strotmeyer ES, Wallace ER, Hoff M, Ceresini G, Rivadeneira F, Uitterlinden AG, Stott DJ, Westendorp RG, Khaw KT, Langhammer A, Ferrucci L, Gussekloo J, Williams GR, Walsh JP, Jüni P, Aujesky D, Rodondi N for the Thyroid Studies Collaboration: Subclinical thyroid dysfunction and fracture risk: a meta-analysis. JAMA 313(20): 2055-65, May 2015.

Cappola AR, Arnold AM, Wulczyn K, Carlson M, Robbins J, Psaty BM: Thyroid function in the euthyroid range and adverse outcomes in older adults. J Clin Endocrinol Metab 100(3): 1088-96, Mar 2015.

Corriere MD, Yao W, Xue QL, Cappola AR, Fried LP, Thorpe RJ, Szanton SL, Kalyani RR : The association of neighborhood characteristics with obesity and metabolic conditions in older women. JNHA 18(9): 792-8, Dec 2014.

Maggio M, Snyder PJ, De Vita F, Ceda GP, Milaneschi Y, Lauretani F, Luci M, Cattabiani C, Peachey H, Valenti G, Cappola AR, Longo DL, Ferrucci L: Effects of transdermal testosterone treatment on inflammatory markers in elderly men. Endocr Pract 20(11): 1170-7, Nov 2014.

Shores MM, Arnold AM, Biggs ML, Longstregth WT, Smith NL, Kizer JR, Cappola AR, Hirsch CH, Marck BT, Matsumoto AM: Testosterone and dihydrotestosterone and incident ischemic stroke in men in the Cardiovascular Health Study. Clin Endocrinol 81(5): 746-53, Nov 2014.

Collet TH, Bauer DC, Cappola AR, Åsvold BO, Weiler S, Vittinghoff E, Gussekloo J, Bremner A, den Elzen WP, Maciel RMB, Vanderpump MP, Cornuz J, Dörr M, Wallaschofski H, Newman AB, Sgarbi JA, Razvi S, Völzke H, Walsh JP, Aujesky D, Rodondi N, for the Thyroid Studies Collaboration: Thyroid antibody status, subclinical hypothyroidism and the risk of coronary heart disease - An individual participant data analysis. J Clin Endocrinol Metab 99(9): 3353-62, Sep 2014.

Garin MC, Arnold AM, Lee JS, Robbins J, Cappola AR: Subclinical thyroid dysfunction and hip fracture and bone mineral density in older adults: the Cardiovascular Health Study. J Clin Endocrinol Metab 99(8): 2657-64, Aug 2014.

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Last updated: 09/19/2016
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