Perelman School of Medicine at the University of Pennsylvania

AEREO: The Consortium to Advance Effective Research Ethics Oversight

Resources

Are you interested in learning more about the problem of evaluating IRB and HRPP effectiveness? These articles are a good place to start:

Abbott, L., & Grady, C. (2011). A systematic review of the empirical literature evaluating IRBs: What we know and what we still need to learn. Journal of Empirical Research on Human Research Ethics, 6(1), 3–19. doi:10.1525/jer.2011.6.1.3

Beagan, B., & McDonald, M. (2005). Evidence-based practice of research ethics review? Health Law Review, 13(2–3), 62–68.

Coleman, C. H., & Bouësseau, M.C. (2008). How do we know that research ethics committees are really working? The neglected role of outcomes assessment in research ethics review. BMC Medical Ethics, 9(1), 6. doi:10.1186/1472-6939-9-6

Donabedian, A. (1988). The quality of care. How can it be assessed? JAMA, 260(12), 1743–1748.

Grady, C. (2010). Do IRBs protect human research participants? Journal of the American Medical Association, 304(10), 1122–1123. doi:10.1001/jama.2010.1304

McDonald, M., & Cox, S. (2009). Moving toward evidence-based human participant protection. Journal of Academic Ethics, 7(1), 1–16.

Nicholls, S. G., Hayes, T. P., Brehaut, J. C., McDonald, M., Weijer, C., Saginur, R., & Fergusson, D. (2015). A scoping review of empirical research relating to quality and effectiveness of research ethics review. PLOS One, 10(7), e0133639. doi:10.1371/journal.pone.0133639

Resnik, D. B. (2015). Some reflections on evaluating institutional review board effectiveness. Contemporary Clinical Trials, 45(Pt B), 261–264. doi:10.1016/j.cct.2015.09.018

Scherzinger, G., & Bobbert, M. (2017). Evaluation of research ethics committees: Criteria for the ethical quality of the review process. Accountability in Research, 24(3), 152–176. doi:10.1080/08989621.2016.1273778

Sugarman, J., Eckenwiler, L., & Emanuel, E. J. (2003). Research oversight through new lenses: The consortium to examine clinical research ethics. IRB: Ethics & Human Research, 25(1), 9–10.

Taylor, H. A. (2007). Moving beyond compliance: measuring ethical quality to enhance the oversight of human subjects research. IRB: Ethics & Human Research, 29(5), 9–14. doi:10.2307/30033242