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4b Jennifer Wei Zou
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Jennifer Wei Zou, Ph.D.
80Associate Professor of Radiation Oncology at the Hospital of the University of Pennsylvania
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Department: Radiation Oncology
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Contact information
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Perelman Center for Advanced Medicine
1e 3400 Civic Center Blvd
41 Radiation Oncology, TRC-2 West
Philadelphia, PA 19104
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1e 3400 Civic Center Blvd
41 Radiation Oncology, TRC-2 West
Philadelphia, PA 19104
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Email:
wei.zou@uphs.upenn.edu
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wei.zou@uphs.upenn.edu
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Education:
21 7 BS 14 (Physics) c
2b Nanjing University, 1993.
21 8 PhD 2e (Theoretical and Applied Mechanics) c
2b Cornell University, 2001.
21 7 MS 1c (Medical Physics) c
33 University of Pennsylvania, 2010.
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Permanent link21 7 BS 14 (Physics) c
2b Nanjing University, 1993.
21 8 PhD 2e (Theoretical and Applied Mechanics) c
2b Cornell University, 2001.
21 7 MS 1c (Medical Physics) c
33 University of Pennsylvania, 2010.
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1d2 Zou W, Dong L, Pin A, Nilsson R, Kim M, Apinorasethkul O, Pakela J, Friberg A, Koger B, Labarbe R, Fuentes CL, Cengel K, Traneus E, Girdhani S, Koumenis C, Vander Stappen F, Diffenderfer E, Bradley J, Teo BK, Lin A: Deliverable proton conformal FLASH radiotherapy treatment planning for head and neck re-irradiation patients. Radiother Oncol. 216, Dec 2025 Notes: 10.1016/j.radonc.2025.111349.
15d Jiang C, McWilliams T, Berger M, Lebow ES, Hubbeling H, Azar E, Kolker JD, Nagda SN, Kurtz G, Zou JW, Scheuermann R, Kumar A, Alonso-Basanta M: Periventricular radionecrosis after conventionally fractionated radiation for low grade meningiomas. Radiat Oncol. 20(1), Nov 2025.
11c Gu W, Shoniyozov K, Mei K, Lin A, Zou W, Dong L, Noël PB, Teo BK: Optimization and fabrication of a novel 3D-printed variable density range modulation device for proton FLASH beams. Med Phys. 52(10), Oct 2025.
16c Friberg AM, Tan HS, Diffenderfer ES, Verginadis I, Kim MM, Cengel K, Wiersma R, Dong L, Koumenis C, Teo BK, Zou W: Physicochemical indication of the FLASH effect from shoot-through proton pencil beam scanning parameters delivered under ultra-high dose rates. Phys Med Biol. 70(17), Aug 2025.
220 Xiao Y, Benedict S, Cui Y, Glide-Hurst C, Graves S, Jia X, Kry SF, Li H, Lin L, Matuszak M, Newpower M, Paganetti H, Qi XS, Roncali E, Rong Y, Sgouros G, Simone CB, II, Sunderland JJ, Taylor PA, Tchelebi L, Weldon M, Zou W, Wuthrick EJ, Machtay M, Le QT, Buchsbaum JC: Embracing the future of clinical trials in radiotherapy: A CIRO technology retreat whitepaper on pioneering technologies and AI-driven solutions. Int. J. Rad. Onc. Bio. Phys. 122(2): 443-457, June 2025.
18e Long M, Alnoury M, Udupa JK, Tong Y, Wu C, Poole N, Mannikeri S, Ky B, Feigenberg SJ, Zou W, O’Reilly S, Torigian DA: Prediction of radiation therapy induced cardiovascular toxicity from pretreatment CT images in patients with thoracic malignancy via an optimal biomarker approach. Acad Radiol 32(4): 1895-1905, April 2025.
1b9 Ni H, Reitman ZJ, Zou W, Akhtar MN, Paul R, Huang M, Zhang D, Zheng H, Zhang R, Ma R, Ngo G, Zhang L, Diffenderfer ES, Motlagh AM, Kim MM, Minn A, Dorsey JF, Foster J, Metz J, Koumenis C, Kirsch DG, Gong Y, Fan Y*: FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy. Nature Cancer 6, February 2025.
186 Oliaei Motlagh S A, Vander Stappen F, Kim M M, Labarbe R, Hotoiu L, Pin A, Nilsson R, Traneus E, Cengel K A, Zou W, Teo B K, Dong L and Diffenderfer ES: Verification of dose and dose rate for quality assurance of spread-out-Bragg-peak proton FLASH radiotherapy using machine log files. Medical Physics mp.17792, 2025.
143 Nilsson R, Pin A, Stappen FV, Hotoiu L, Fuentes C, Kim M, Diffenderfer E, Dong L, Zou W, Teo BK, Traneus E, Engwall E: TPS Dose Validation for Proton Conformal FLASH Treatment on the IBA ProteusPlus FLASH system. FRPT, Rome, Italy 2024 Notes: Poster.
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Selected Publications
235 egya-Raman N, Ko K, Han IS, Mitchell JD, Zou W, Ohri N, Jabbour SK, Mak RH, Robinson C, Levin WP, Barrett L, Xia C, Berlin E, Bravo P, Carli MD, Cohen R, Hutton S, Keltz J, Wang J, Fasan O, Nagda SN, Seo A, Smith AM, Sun L, Soike M, Kole AJ, Walls G, Feigenberg SJ, Ky B: Cardiac substructure radiotherapy dose and changes in physical activity and quality of life after chemoradiotherapy for NSCLC: a secondary analysis of the CLARITY prospective study. Clin Transl Radiat Oncol 56, Jan 2026.1d2 Zou W, Dong L, Pin A, Nilsson R, Kim M, Apinorasethkul O, Pakela J, Friberg A, Koger B, Labarbe R, Fuentes CL, Cengel K, Traneus E, Girdhani S, Koumenis C, Vander Stappen F, Diffenderfer E, Bradley J, Teo BK, Lin A: Deliverable proton conformal FLASH radiotherapy treatment planning for head and neck re-irradiation patients. Radiother Oncol. 216, Dec 2025 Notes: 10.1016/j.radonc.2025.111349.
15d Jiang C, McWilliams T, Berger M, Lebow ES, Hubbeling H, Azar E, Kolker JD, Nagda SN, Kurtz G, Zou JW, Scheuermann R, Kumar A, Alonso-Basanta M: Periventricular radionecrosis after conventionally fractionated radiation for low grade meningiomas. Radiat Oncol. 20(1), Nov 2025.
11c Gu W, Shoniyozov K, Mei K, Lin A, Zou W, Dong L, Noël PB, Teo BK: Optimization and fabrication of a novel 3D-printed variable density range modulation device for proton FLASH beams. Med Phys. 52(10), Oct 2025.
16c Friberg AM, Tan HS, Diffenderfer ES, Verginadis I, Kim MM, Cengel K, Wiersma R, Dong L, Koumenis C, Teo BK, Zou W: Physicochemical indication of the FLASH effect from shoot-through proton pencil beam scanning parameters delivered under ultra-high dose rates. Phys Med Biol. 70(17), Aug 2025.
220 Xiao Y, Benedict S, Cui Y, Glide-Hurst C, Graves S, Jia X, Kry SF, Li H, Lin L, Matuszak M, Newpower M, Paganetti H, Qi XS, Roncali E, Rong Y, Sgouros G, Simone CB, II, Sunderland JJ, Taylor PA, Tchelebi L, Weldon M, Zou W, Wuthrick EJ, Machtay M, Le QT, Buchsbaum JC: Embracing the future of clinical trials in radiotherapy: A CIRO technology retreat whitepaper on pioneering technologies and AI-driven solutions. Int. J. Rad. Onc. Bio. Phys. 122(2): 443-457, June 2025.
18e Long M, Alnoury M, Udupa JK, Tong Y, Wu C, Poole N, Mannikeri S, Ky B, Feigenberg SJ, Zou W, O’Reilly S, Torigian DA: Prediction of radiation therapy induced cardiovascular toxicity from pretreatment CT images in patients with thoracic malignancy via an optimal biomarker approach. Acad Radiol 32(4): 1895-1905, April 2025.
1b9 Ni H, Reitman ZJ, Zou W, Akhtar MN, Paul R, Huang M, Zhang D, Zheng H, Zhang R, Ma R, Ngo G, Zhang L, Diffenderfer ES, Motlagh AM, Kim MM, Minn A, Dorsey JF, Foster J, Metz J, Koumenis C, Kirsch DG, Gong Y, Fan Y*: FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy. Nature Cancer 6, February 2025.
186 Oliaei Motlagh S A, Vander Stappen F, Kim M M, Labarbe R, Hotoiu L, Pin A, Nilsson R, Traneus E, Cengel K A, Zou W, Teo B K, Dong L and Diffenderfer ES: Verification of dose and dose rate for quality assurance of spread-out-Bragg-peak proton FLASH radiotherapy using machine log files. Medical Physics mp.17792, 2025.
143 Nilsson R, Pin A, Stappen FV, Hotoiu L, Fuentes C, Kim M, Diffenderfer E, Dong L, Zou W, Teo BK, Traneus E, Engwall E: TPS Dose Validation for Proton Conformal FLASH Treatment on the IBA ProteusPlus FLASH system. FRPT, Rome, Italy 2024 Notes: Poster.
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