Gary Freedman
Gary Freedman, M.D.
Professor of Radiation Oncology at the Hospital of the University of Pennsylvania
Department: Radiation Oncology
Contact information
Radiation Oncology
Perelman School of Medicine
PCAM / TRC 4 West
3400 Civic Center Blvd
Philadelphia, PA 19104
Perelman School of Medicine
PCAM / TRC 4 West
3400 Civic Center Blvd
Philadelphia, PA 19104
Office: 215-615-6767
Education:
B.A. (Classics)
University of Virginia, 1988.
M.D. (Medicine)
Temple University School of Medicine, 1993.
Permanent linkB.A. (Classics)
University of Virginia, 1988.
M.D. (Medicine)
Temple University School of Medicine, 1993.
Description of Clinical Expertise
My academic and clinical practice is limited to breast cancer. I serve as the clinical chief of the breast service for the Department of Radiation Oncology. I was recognized by Penn Medicine for clinical excellence by induction into the Academy of Master Clinicians in 2013. I have been recognized by my peers with the honor of inclusion in the 2009 - 2024 Castle Connolly / Philadelphia Top Doctors.Description of Research Expertise
I have an academic focus limited to breast cancer. My research interests have been focused on shortening radiation courses by hypofractionation, intensity modulated radiation therapy (IMRT) with concurrent boost, proton beam radiation, and cardiac effects of radiation therapy/techniques to reduce cardiac dose in breast cancer. I have published over 100 peer-reviewed manuscripts, review articles and book chapters about breast cancer, radiation for early and advanced stage disease, radiation for intact breast and post-mastectomy indications, and radiation therapy techniques and side effects.Selected Publications
Choi JI, Freedman G, Guttman D, Ahmed K, Gao W, Walker E, Harris L, Gonzalez V, Ye J, Nead K, Taunk N, Tadros A, Dang C, Daroui P, Novick K: Executive Summary of the American Radium Society (ARS) Appropriate Use Criteria (AUC): Regional Nodal Irradiation for Breast Cancer. American Journal of Clinical Oncology 48(3), March 2025 Notes: Accepted for publication 8/14/2024.Berlin E, Ko K, Ma L, Messing I, Hollawell C, Smith AM, Taunk NK, Narayan V, Upshaw JN, Clark AS, Shah PD, Knollman H, Bhattacharya S, Koropeckyj-Cox D, Wang J, Yegya-Raman N, Han IS, Lefebvre B, Li T, Wilcox NS, Jung W, Chen J, Freedman GM, Ky B: Cardiac Effects of Modern Breast Radiation Therapy in Patients Receiving Systemic Cancer Therapy. JACC: CardioOncology 2025 Notes: Accepted 1/15/2025.
Cederquist GY, Boe LA, Walsh M, Freedman GM, Maxwell KN, Taunk N, Braunstein LZ: Radiation-Associated Secondary Cancer in Patients With Breast Cancer Harboring TP53 Germline Variants. JAMA Oncology 9 2024 Notes: doi:10.1001/jamaoncol.2024.3683.
Hahn EA, Pugh SL, Lu HL, Vela AM, Gillespie EF, Nichols EM, Wright JL, MacDonald SM, Cahlon O, Baas C, Braunstein LZ, Fang LC, Freedman GM, Jimenez RB, Kesslering CM, Mishra MV, Mutter RW, Ohri N, Rosen LR, Urbanic JJ, Jagsi R, Mitchell SA, Bekelman JE, Cella D; RadComp (Radiotherapy Comparative Effectiveness Consortium). : Validation of Patient-Reported Outcomes in Patients With Nonmetastatic Breast Cancer Receiving Comprehensive Nodal Irradiation in the RadComp Trial. Int J Radiat Oncol Biol Phys 120: 149-161, 2024 Notes: doi.org/10.1016/j.ijrobp.2024.03.020.
Iwai Y, Perez-Rojas S, Thomas SM, Tadros AB, Woodward SG, Zhang JQ, Elmore LC, Freedman GM, Tchou JC, Bleznak AD, Fayanju OM: Guideline-Concordant Surgical Care for Lobular Versus Ductal Inflammatory Breast Cancer. Ann Surg Oncol 2024 Notes: doi: 10.1245/s10434-024-15540-1.
Freedman GM, Li T, Garver E, Shillington K, Shinkle B, Tchou JC, Fayanju OM, Lin L, Taunk NK: Five-year outcomes of a phase I/II trial of accelerated partial breast irradiation using proton therapy for women with stage 0-IIA breast cancer. Advances in Radiation Oncology 9(2), July 2023 Notes: Accepted for publication 7/21/2023 https://doi.org/10.1016/j.adro.2023.101334.
Manik R, Grady CB, Elmore LC, Fieber JH, Freedman GM, Jankowitz RC, Tchou JC, Zhang JQ, Hubbard RA, Fayanju OM: Temporal Trends and Factors Associated with Receipt of Post-Mastectomy Radiation after Neoadjuvant Chemotherapy in Women with cT3 Breast Cancer. ASO 2023 Notes: Accepted 5/25/2023 https://doi.org/10.1245/s10434-023-13730-x.
Novick K, Chadha M, Daroui P, Freedman G, Gao W, Hunt K, Park C, Rewari A, Suh W, Walker W, Wong J, Harris EE: American Radium Society Appropriate Use Criteria Postmastectomy Radiation Therapy: Executive Summary of Clinical Topics. Int J Radiat Oncol Biol Phys 2023.
Berlin E, Yegya-Raman N, Hollawell C, Haertter A, Rhodes S, Seol S, Gentile M, Li T, Freedman GM, Taunk NK : Breast Reconstruction Complications Following Post-Mastectomy Proton Radiotherapy for Breast Cancer. Advances in Radiation Oncology 9(3), 2023 Notes: https://doi.org/10.1016/j.adro.2023.101385.
Jagsi R, Griffith KA, Harris EE, Wright JL, Recht A, Taghian AG, Lee L, Moran MS, Small Jr W, Johnstone C, Rahimi A, Freedman G, Muzaffar M, Haffty B, Horst K, Powell SN, Sharp J, Sabel M, Schott A, El-Tamer M: Omission of Radiotherapy After Breast-Conserving Surgery for Women With Breast Cancer With Low Clinical and Genomic Risk: 5-Year Outcomes of IDEA. J Clin Oncol 2023 Notes: Accepted for publication 10/24/2023.